Cheap flights from MDT to SDF (Harrisburg Intl. to Louisville Intl.)

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Cheap Flights from MDT to SDF starting at $234 One Way, $249 Round Trip

Prices starting at $249 for return flights and $234 for one-way flights to Louisville Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Feb 26 - Mon, Mar 2
MDT
Harrisburg
SDF
Louisville
$249 Roundtrip, found 13 hours ago
$249
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Thu, Feb 26 from Harrisburg to Louisville, returning Mon, Mar 2, priced at $249 found 13 hours ago
Sat, Feb 21 - Fri, Feb 27
MDT
Harrisburg
SDF
Louisville
$254 Roundtrip, found 6 days ago
$254
Roundtrip
found 6 days ago
Select Delta flight, departing Sat, Feb 21 from Harrisburg to Louisville, returning Fri, Feb 27, priced at $254 found 6 days ago
Thu, Feb 26 - Mon, Mar 2
MDT
Harrisburg
SDF
Louisville
$274 Roundtrip, found 13 hours ago
$274
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Thu, Feb 26 from Harrisburg to Louisville, returning Mon, Mar 2, priced at $274 found 13 hours ago
Sat, Feb 21 - Mon, Feb 23
MDT
Harrisburg
SDF
Louisville
$288 Roundtrip, found 6 days ago
$288
Roundtrip
found 6 days ago
Select Delta flight, departing Sat, Feb 21 from Harrisburg to Louisville, returning Mon, Feb 23, priced at $288 found 6 days ago
Thu, Feb 26 - Sat, Feb 28
MDT
Harrisburg
SDF
Louisville
$297 Roundtrip, found 6 days ago
$297
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Feb 26 from Harrisburg to Louisville, returning Sat, Feb 28, priced at $297 found 6 days ago

Hotel Ideas near Louisville Intl.

Airport Hotels near Louisville Intl.

Crowne Plaza Louisville Airport Expo Ctr by IHG

Crowne Plaza Louisville Airport Expo Ctr by IHG

3.5 out of 5
830 Phillips Lane Louisville KY
$104 nightly
The price is $122 total per night from Jan 12 to Jan 13
$122 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the ...
8.8/10 Excellent! (1,023 reviews)
Service great all around!

Reviewed on Dec 11, 2025

Crowne Plaza Louisville Airport Expo Ctr by IHG
Studio 6 Suites Louisville, KY – Airport/Expo Center

Studio 6 Suites Louisville, KY – Airport/Expo Center

2 out of 5
571 Phillips Ln Louisville KY
$59 nightly
The price is $69 total per night from Dec 15 to Dec 16
$69 total
Dec 15 - Dec 16
Total with taxes and fees
Stay at this hotel in Louisville. Enjoy free parking, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms in ...
7.2/10 Good! (507 reviews)
Everything is excelent

Reviewed on Nov 30, 2025

Studio 6 Suites Louisville, KY – Airport/Expo Center
Courtyard by Marriott Louisville Airport

Courtyard by Marriott Louisville Airport

3 out of 5
819 Phillips Lane Louisville KY
$98 nightly
The price is $115 total per night from Dec 16 to Dec 17
$115 total
Dec 16 - Dec 17
Total with taxes and fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
9/10 Wonderful! (328 reviews)
Easy, helpful staff, clean and quick airport shuttle

Reviewed on Dec 8, 2025

Courtyard by Marriott Louisville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Louisville

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
$133 nightly
The price is $157 total per night from Dec 20 to Dec 21
$157 total
Dec 20 - Dec 21
Total with taxes and fees
Book a stay at this spa hotel in Louisville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the restaurant and the helpful staff ...
8.8/10 Excellent! (3,859 reviews)
Yes

Reviewed on Dec 14, 2025

Galt House Hotel Trademark Collection by Wyndham
Omni Louisville Hotel

Omni Louisville Hotel

4 out of 5
400 S. 2nd Street Louisville KY
$167 nightly
The price is $197 total per night from Jan 1 to Jan 2
$197 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Book a stay at this spa hotel in Louisville. Enjoy a full-service spa, 3 restaurants, and 3 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,727 reviews)
Beautiful hotel located in a great spot with very nice staff!

Reviewed on Dec 13, 2025

Omni Louisville Hotel
Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
$63 nightly
The price is $71 total per night from Dec 20 to Dec 21
$71 total
Dec 20 - Dec 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Clarksville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the clean rooms in our reviews. ...
6.8/10 (2,622 reviews)
All around awesome

Reviewed on Dec 13, 2025

Radisson Hotel Louisville North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Louisville Hotels With Airport Transportation

The Brown Hotel

The Brown Hotel

4.5 out of 5
335 W Broadway Louisville KY
$168 nightly
The price is $198 total per night from Dec 17 to Dec 18
$198 total
Dec 17 - Dec 18
Total with taxes and fees
Book a stay at this luxury hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,154 reviews)
The hotel is historic and beautiful. You feel like you’ve been transported back in time which is a cool feeling. Staff was nice, dinner at the restaurant was exceptional. They also had a hot chocolate station which was cute. The beds… not luxurious so as long as you don’t have back problems or are ...

Reviewed on Dec 13, 2025

The Brown Hotel
Holiday Inn Express Louisville Airport Expo Center by IHG

Holiday Inn Express Louisville Airport Expo Center by IHG

2.5 out of 5
1921 Bishop Ln Louisville KY
$91 nightly
The price is $107 total per night from Dec 21 to Dec 22
$107 total
Dec 21 - Dec 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,000 reviews)
Everyone and everything was excellent specially the kitchen ladie

Reviewed on Dec 9, 2025

Holiday Inn Express Louisville Airport Expo Center by IHG
Howard Johnson by Wyndham Airport

Howard Johnson by Wyndham Airport

2 out of 5
709 Phillips Lane Louisville KY
Book a stay at this business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (999 reviews)
Great stay

Reviewed on Jan 28, 2025

Get rates
Howard Johnson by Wyndham Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Louisville Hotels

Econo Lodge Louisville Downtown

Econo Lodge Louisville Downtown

2 out of 5
401 S 2nd St Louisville KY
$60 nightly
The price is $71 total per night from Dec 28 to Dec 29
$71 total
Dec 28 - Dec 29
Total with taxes and fees
Book a stay at this business-friendly motel in Louisville. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
7/10 Good! (1,000 reviews)
The room was fine, the staff was courteous, the breakfast was sufficient. A nice stay thank you

Reviewed on Dec 6, 2025

Econo Lodge Louisville Downtown
Red Roof Inn Louisville Fair and Expo

Red Roof Inn Louisville Fair and Expo

2 out of 5
3322 Red Roof Inn Pl Louisville KY
$60 nightly
The price is $70 total per night from Dec 22 to Dec 23
$70 total
Dec 22 - Dec 23
Total with taxes and fees
Stay at this hotel in Louisville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (1,001 reviews)
It's on I give 5 stars because I didn't stay all night

Reviewed on Dec 3, 2025

Red Roof Inn Louisville Fair and Expo
Super 8 by Wyndham Louisville Airport

Super 8 by Wyndham Louisville Airport

2.5 out of 5
4800 Preston Hwy Louisville KY
$60 nightly
The price is $71 total per night from Dec 15 to Dec 16
$71 total
Dec 15 - Dec 16
Total with taxes and fees
Book a stay at this business-friendly motel in Louisville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
4.6/10 (1,002 reviews)
Great clean affordable room

Reviewed on Dec 5, 2025

Super 8 by Wyndham Louisville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Louisville

Drury Inn & Suites Louisville North

Drury Inn & Suites Louisville North

3 out of 5
9597 Brownsboro Road Louisville KY
$100 nightly
The price is $118 total per night from Dec 15 to Dec 16
$118 total
Dec 15 - Dec 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Louisville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,007 reviews)
I always have a wonderful stay at any Drury. Clean, comfortable, friendly, good food, great customer service

Reviewed on Dec 14, 2025

Drury Inn & Suites Louisville North
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4 out of 5
140 North Fourth Street Louisville KY
$133 nightly
The price is $157 total per night from Dec 20 to Dec 21
$157 total
Dec 20 - Dec 21
Total with taxes and fees
Book a stay at this spa hotel in Louisville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the restaurant and the helpful staff ...
8.8/10 Excellent! (3,859 reviews)
Yes

Reviewed on Dec 14, 2025

Galt House Hotel Trademark Collection by Wyndham
Country Inn & Suites by Radisson, Louisville South, KY

Country Inn & Suites by Radisson, Louisville South, KY

2 out of 5
400 Paroquet Springs Drive Shepherdsville KY
$85 nightly
The price is $94 total per night from Dec 21 to Dec 22
$94 total
Dec 21 - Dec 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Shepherdsville. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
7.8/10 Good! (1,001 reviews)
Staff was extremely helpful

Reviewed on Nov 25, 2025

Country Inn & Suites by Radisson, Louisville South, KY
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MDT to SDF Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

Are there non-stop flights from Harrisburg Intl. Airport to SDF?
There are no direct flights on this route. But American Airlines, Delta Air Lines and United Airlines can get you from Harrisburg Intl. Airport to SDF with just one stopover.
What is the shortest flight from Harrisburg Intl. Airport to Louisville Muhammad Ali Intl. Airport?
Flying from Harrisburg Intl. Airport to SDF takes at least 3 hours and 46 minutes. Indulge in a tipple and read a few magazines — this is your chance to chill out.
How many hours flight from Harrisburg Intl. Airport (MDT) to Louisville Muhammad Ali Intl. Airport?
Settle in and get comfortable, because the average journey from Harrisburg Intl. Airport to SDF is 3 hours and 51 minutes. Watch a few movies, finish that book … You'll have ample time to rest and unwind.
What airlines have the most flights from Harrisburg Intl. Airport (MDT) to SDF?
Indulge in some people-watching, have a coffee, stretch your legs … Airport stopovers don't have to be dull! If you're planning to head between Harrisburg and Louisville, you won't be able to fly direct. Prepare for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.