Cheap flights from MDT to BRU (Harrisburg Intl. to Brussels - National)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from MDT to BRU starting at $546 One Way, $1,107 Round Trip

Prices starting at $1,107 for return flights and $546 for one-way flights to Brussels - National were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, May 25 - Sat, May 29
MDT
Harrisburg
BRU
Brussels
$1,107 Roundtrip, found 1 day ago
$1,107
Roundtrip
found 1 day ago
Select British Airways flight, departing Tue, May 25 from Harrisburg to Brussels, returning Sat, May 29, priced at $1,107 found 1 day ago
Tue, May 25 - Sat, May 29
MDT
Harrisburg
BRU
Brussels
$1,109 Roundtrip, found 1 day ago
$1,109
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, May 25 from Harrisburg to Brussels, returning Sat, May 29, priced at $1,109 found 1 day ago
Tue, May 25 - Sat, May 29
MDT
Harrisburg
BRU
Brussels
$1,110 Roundtrip, found 1 day ago
$1,110
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, May 25 from Harrisburg to Brussels, returning Sat, May 29, priced at $1,110 found 1 day ago
Tue, May 25 - Sat, May 29
MDT
Harrisburg
BRU
Brussels
$1,136 Roundtrip, found 1 day ago
$1,136
Roundtrip
found 1 day ago
Select British Airways flight, departing Tue, May 25 from Harrisburg to Brussels, returning Sat, May 29, priced at $1,136 found 1 day ago
Tue, May 25 - Sat, May 29
MDT
Harrisburg
BRU
Brussels
$1,149 Roundtrip, found 1 day ago
$1,149
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, May 25 from Harrisburg to Brussels, returning Sat, May 29, priced at $1,149 found 1 day ago

Hotel Ideas near Brussels - National

Brussels Hotels With Airport Transportation

Novotel Brussels Airport

Novotel Brussels Airport

3.5 out of 5
Da vinci laan 25 Machelen Flemish Brabant
$94 nightly
The price is $112 total per night from Nov 1 to Nov 2
$112 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this family-friendly hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.6/10 Excellent! (1,002 reviews)
"To rate everything as excellent seems a bit over the top even to me, but I could not find a fault with this hotel. The hotel was handy to the airport and the shuttle was easy to catch and seems to run more frequently than posted. The staff at the front desk, in particular Adam, were wonderful, kind ..."

Reviewed on Oct 1, 2026

Novotel Brussels Airport
ibis budget Brussels Airport

ibis budget Brussels Airport

1 out of 5
Bessenveldstraat Machelen
$53 nightly
The price is $65 total per night from Oct 25 to Oct 26
$65 total
Oct 25 - Oct 26
Total with taxes and fees
Stay at this hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our ...
ibis budget Brussels Airport
ibis Brussels Airport

ibis Brussels Airport

3 out of 5
Bessenveldstraat 17 Machelen
$68 nightly
The price is $83 total per night from Oct 30 to Oct 31
$83 total
Oct 30 - Oct 31
Total with taxes and fees
Stay at this hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the property condition in our reviews. Popular ...
ibis Brussels Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Brussels Hotels

easyHotel Brussels City Centre

easyHotel Brussels City Centre

Zilverstraat 1 Brussels
$95 nightly
The price is $112 total per night from Oct 18 to Oct 19
$112 total
Oct 18 - Oct 19
Total with taxes and fees
Stay at this hotel in Brussels. Enjoy free WiFi, a 24-hour front desk, and memory foam beds. Our guests praise the helpful staff and the clean rooms in our reviews. ...
easyHotel Brussels City Centre
ibis budget Brussels Airport

ibis budget Brussels Airport

1 out of 5
Bessenveldstraat Machelen
$53 nightly
The price is $65 total per night from Oct 25 to Oct 26
$65 total
Oct 25 - Oct 26
Total with taxes and fees
Stay at this hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our ...
ibis budget Brussels Airport
Bedford Hotel & Congress Centre

Bedford Hotel & Congress Centre

3.5 out of 5
Rue Du Midi 135 Brussels
$121 nightly
The price is $142 total per night from Oct 25 to Oct 26
$142 total
Oct 25 - Oct 26
Total with taxes and fees
Book a stay at this business-friendly hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the breakfast and the ...
8.4/10 Very Good! (1,006 reviews)
"Staff were incredibly lovely and helpful, room was very clean and bed really comfortable! My only quibbles are the lack of power sockets on both sides of the bed… and the sparse coffee/tea provisions. The cups for hot drinks were also just cardboard cups. Breakfast options were pastries, scrambled ..."

Reviewed on Oct 3, 2026

Bedford Hotel & Congress Centre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MDT to BRU Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

What is the shortest flight from MDT to Brussels Airport?
With the quickest flight time from Harrisburg Intl. Airport (MDT) to Brussels - National Airport (BRU) being 9 hours and 20 minutes, it's smart to have some in-flight survival tricks up your sleeve. An eye-mask, a neck pillow and earplugs should be among the essentials you put in your hand luggage.
How many hours flight from Harrisburg Intl. Airport (MDT) to BRU?
The trip from MDT to Brussels Airport typically lasts about 9 hours and 21 minutes. Make this long-haul flight go by a little faster by bringing your laptop full of your favorite flicks.
What airlines have the most flights from Harrisburg Intl. Airport (MDT) to BRU?
Watch the planes take off and land, grab a glazed doughnut, stretch your legs … Airport stopovers don't have to be boring! If you're planning to head from Harrisburg Intl. Airport to Brussels Airport, you can't fly direct. Be prepared for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.