Cheap flights from EYW to SAN (Key West Intl. to San Diego Intl.)

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Cheap Flights from EYW to SAN starting at $238 One Way, $465 Round Trip

Prices starting at $465 for return flights and $238 for one-way flights to San Diego Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, May 9 - Tue, May 13
EYW
Key West
SAN
San Diego
$465 Roundtrip, found 3 hours ago
$465
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Fri, May 9 from Key West to San Diego, returning Tue, May 13, priced at $465 found 3 hours ago
Fri, May 9 - Tue, May 13
EYW
Key West
SAN
San Diego
$465 Roundtrip, found 3 hours ago
$465
Roundtrip
found 3 hours ago
Select Delta flight, departing Fri, May 9 from Key West to San Diego, returning Tue, May 13, priced at $465 found 3 hours ago
Fri, May 9 - Tue, May 13
EYW
Key West
SAN
San Diego
$563 Roundtrip, found 3 hours ago
$563
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Fri, May 9 from Key West to San Diego, returning Tue, May 13, priced at $563 found 3 hours ago
Fri, May 9 - Tue, May 13
EYW
Key West
SAN
San Diego
$566 Roundtrip, found 3 hours ago
$566
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Fri, May 9 from Key West to San Diego, returning Tue, May 13, priced at $566 found 3 hours ago
Sat, May 3 - Fri, May 9
EYW
Key West
SAN
San Diego
$574 Roundtrip, found 2 days ago
$574
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sat, May 3 from Key West to San Diego, returning Fri, May 9, priced at $574 found 2 days ago

Hotel Ideas near San Diego Intl.

Airport Hotels near San Diego Intl.

Sheraton San Diego Resort
Sheraton San Diego Resort
4 out of 5
1380 Harbor Island Dr, San Diego, CA
The price is $236 per night from May 12 to May 13
$236
includes taxes & fees
$205 per night
May 12 - May 13
Book a stay at this business-friendly hotel in San Diego. Enjoy 3 outdoor pools, 5 restaurants, and a marina. Our guests praise the pool and the restaurant in ...
8/10 Very Good! (2,615 reviews)
"No view"

Reviewed on Apr 28, 2025

Sheraton San Diego Resort
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is $176 per night from May 11 to May 12
$176
includes taxes & fees
$152 per night
May 11 - May 12
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,666 reviews)
"We arrived in San Diego via cruise ship and choose the Wyndam because of it's proximity to the cruise port. A short (under 5 mins) walk got us to our destination. There is a lot to do in the area and also plenty of dining options. The hotel is very nice, the staff members that we spoke with were ..."

Reviewed on Apr 28, 2025

Wyndham San Diego Bayside
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2.5 out of 5
2485 Hotel Circle Place, San Diego, CA
The price is $152 per night from May 7 to May 8
$152
includes taxes & fees
$132 per night
May 7 - May 8
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,560 reviews)
"This place was great for our family of 6. The bunkbeds were a welcomed addition so everyone could sleep separately. The staff were some of the friendliest we've encountered. The breakfast was good but repetative if you are staying for long than a couple nights. The laundry facilities were great and ..."

Reviewed on May 1, 2025

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In San Diego

San Diego Mission Bay Resort
San Diego Mission Bay Resort
4 out of 5
1775 E Mission Bay Dr, San Diego, CA
The price is $285 per night from May 11 to May 12
$285
includes taxes & fees
$248 per night
May 11 - May 12
Book a stay at this beach hotel in San Diego. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the pool and the helpful staff in our ...
8.2/10 Very Good! (1,191 reviews)
"Family friendly ❤️"

Reviewed on Apr 29, 2025

San Diego Mission Bay Resort
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2.5 out of 5
2485 Hotel Circle Place, San Diego, CA
The price is $152 per night from May 7 to May 8
$152
includes taxes & fees
$132 per night
May 7 - May 8
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,560 reviews)
"This place was great for our family of 6. The bunkbeds were a welcomed addition so everyone could sleep separately. The staff were some of the friendliest we've encountered. The breakfast was good but repetative if you are staying for long than a couple nights. The laundry facilities were great and ..."

Reviewed on May 1, 2025

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is $176 per night from May 11 to May 12
$176
includes taxes & fees
$152 per night
May 11 - May 12
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,666 reviews)
"We arrived in San Diego via cruise ship and choose the Wyndam because of it's proximity to the cruise port. A short (under 5 mins) walk got us to our destination. There is a lot to do in the area and also plenty of dining options. The hotel is very nice, the staff members that we spoke with were ..."

Reviewed on Apr 28, 2025

Wyndham San Diego Bayside
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Diego Hotels With Airport Transportation

Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is $176 per night from May 11 to May 12
$176
includes taxes & fees
$152 per night
May 11 - May 12
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,666 reviews)
"We arrived in San Diego via cruise ship and choose the Wyndam because of it's proximity to the cruise port. A short (under 5 mins) walk got us to our destination. There is a lot to do in the area and also plenty of dining options. The hotel is very nice, the staff members that we spoke with were ..."

Reviewed on Apr 28, 2025

Wyndham San Diego Bayside
Sheraton San Diego Resort
Sheraton San Diego Resort
4 out of 5
1380 Harbor Island Dr, San Diego, CA
The price is $236 per night from May 12 to May 13
$236
includes taxes & fees
$205 per night
May 12 - May 13
Book a stay at this business-friendly hotel in San Diego. Enjoy 3 outdoor pools, 5 restaurants, and a marina. Our guests praise the pool and the restaurant in ...
8/10 Very Good! (2,615 reviews)
"No view"

Reviewed on Apr 28, 2025

Sheraton San Diego Resort
Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 out of 5
1955 San Diego Ave, San Diego, CA
The price is $176 per night from May 5 to May 6
$176
includes taxes & fees
$153 per night
May 5 - May 6
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
8.8/10 Excellent! (1,006 reviews)
"Great customer service,! Clean facilities!"

Reviewed on May 1, 2025

Holiday Inn Express San Diego Airport - Old Town by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced San Diego Hotels

Pleasant Inn
Pleasant Inn
2.5 out of 5
5550 Clairemont Mesa Blvd, San Diego, CA
The price is $114 per night from May 3 to May 4
$114
includes taxes & fees
$99 per night
May 3 - May 4
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the convenient parking in our ...
8.4/10 Very Good! (1,008 reviews)
"It would’ve been nice to offer at least a continental breakfast. Also a pool or hot tub would be nice here"

Reviewed on Apr 27, 2025

Pleasant Inn
E-Z 8 Motel Old Town
E-Z 8 Motel Old Town
2.5 out of 5
4747 Pacific Highway, San Diego, CA
The price is $90 per night from May 4 to May 5
$90
includes taxes & fees
$78 per night
May 4 - May 5
Book a stay at this business-friendly hotel in San Diego. Enjoy free parking, WiFi (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
6.2/10 (2,023 reviews)
"N/A"

Reviewed on Apr 29, 2025

E-Z 8 Motel Old Town
Kings Inn San Diego
Kings Inn San Diego
2.5 out of 5
1333 Hotel Cir S, San Diego, CA
The price is $116 per night from May 6 to May 7
$116
includes taxes & fees
$102 per night
May 6 - May 7
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the breakfast and the pool in our reviews. Popular ...
8.6/10 Excellent! (3,212 reviews)
"Clean basic no-frills hotel room in a convenient location at a reasonable price. Restaurant on-location. Would stay again."

Reviewed on Apr 30, 2025

Kings Inn San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in San Diego

Bahia Resort Hotel
Bahia Resort Hotel
3.5 out of 5
998 W Mission Bay Dr, San Diego, CA
The price is $257 per night from May 8 to May 9
$257
includes taxes & fees
$223 per night
May 8 - May 9
Book a stay at this beach resort in San Diego. Enjoy free parking, a beach locale, and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
8.4/10 Very Good! (1,520 reviews)
"Bayfront means bottom in front of beach . Bayview means just some sort of room with some what of a water view pictures are not accurate"

Reviewed on Apr 29, 2025

Bahia Resort Hotel
The Dana on Mission Bay
The Dana on Mission Bay
3.5 out of 5
1710 W Mission Bay Dr, San Diego, CA
The price is $194 per night from May 11 to May 12
$194
includes taxes & fees
$169 per night
May 11 - May 12
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (3,336 reviews)
"Clean and very nice! Pool area is also beautiful."

Reviewed on Apr 29, 2025

The Dana on Mission Bay
Catamaran Resort and Spa
Catamaran Resort and Spa
4 out of 5
3999 Mission Boulevard, San Diego, CA
The price is $279 per night from May 18 to May 19
$279
includes taxes & fees
$242 per night
May 18 - May 19
Book a stay at this beach resort in San Diego. Enjoy free WiFi, a full-service spa, and a beach locale. Our guests praise the helpful staff and the clean rooms ...
8/10 Very Good! (1,002 reviews)

Families like: Outdoor pool, game room, on the beach, bicycle rentals

Travelers say...
"The view from the Tower (Bay View) was incredible. The room was clean and we loved sitting out on the balcony, set with a bistro sized table and two chairs. The view is a big plus. That being said, the room and tower in general need some updating. The decor is kinda 90’s tropical. Outdated. I didn’t ..."

Reviewed on Apr 29, 2025

Catamaran Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

EYW to SAN Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
EYW Address & GPS
Address:
3491 South Roosevelt Boulevard
Key West FL, 33040-5260
United States
IATA Code:
EYW
Longitude:
-81.75501
Latitude:
24.553574
Time Zone:
America/New_York
SAN Address & GPS
Address:
Airport Drive
San Diego CA, 92101
United States
IATA Code:
SAN
Longitude:
-117.197312
Latitude:
32.731938
Time Zone:
America/Los_Angeles

Frequently asked questions

Am I able to catch a flight from Key West, FL Airport (EYW-Key West Intl.) to San Diego, CA Airport (SAN-San Diego Intl.) now?
If you’re worried about quarantine and travel restrictions when catching a flight from Key West, FL Airport (EYW-Key West Intl.) to San Diego, CA Airport (SAN-San Diego Intl.), go right to the Covid-19 Travel Advisor.
Are there non-stop flights from EYW to San Diego, CA Airport (SAN-San Diego Intl.)?
Traveling from Key West, FL Airport (EYW-Key West Intl.) to San Diego, CA Airport (SAN-San Diego Intl.)? Breaking up the journey is your one and only option as there are no airlines that run nonstop on this route. However, American Airlines, United Airlines and Qatar Airways offer the next best thing — a flight with just a single stopover.
What is the shortest flight from Key West, FL Airport (EYW-Key West Intl.) to San Diego Airport?
Grab the opportunity to relax on your way from Summerland Key to Leucadia. The quickest flight time from Key West, FL Airport (EYW-Key West Intl.) to San Diego Airport is 7 hours and 34 minutes, which gives you ample time to enjoy a wine or get absorbed in a good book.
How many hours flight from Key West, FL Airport (EYW-Key West Intl.) to SAN?
Make yourself comfortable, because a typical plane trip from Key West Intl. Airport (EYW) to San Diego, CA Airport (SAN-San Diego Intl.) is 7 hours and 39 minutes. Watch a few movies, stick your nose in a book … You’ll have ample time to relax and enjoy the ride.
If I am not able to travel due to COVID-19, can I cancel my flight to San Diego, CA Airport (SAN-San Diego Intl.)?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to San Diego, CA Airport (SAN-San Diego Intl.) have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to San Diego, CA Airport (SAN-San Diego Intl.) with flexible change policies?
In most cases you’ll have the option to reschedule your flight to San Diego, CA Airport (SAN-San Diego Intl.) without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What airlines have the most flights from Key West Intl. Airport to SAN?
If you’re wanting to find an airline that operates direct flights from Key West Intl. Airport (EYW) to San Diego Airport, you won’t have much luck. You’ll have to make at least one stop to get to your destination.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.