Cheap flights from COU to TYS (Columbia Regional to McGhee Tyson)

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Cheap Flights from COU to TYS starting at One Way, $464 Round Trip

Prices starting at $464 for return flights and for one-way flights to McGhee Tyson were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Sep 9 - Thu, Sep 18
COU
Columbia
TYS
Knoxville
$464 Roundtrip, found 1 day ago
$464
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Sep 9 from Columbia to Knoxville, returning Thu, Sep 18, priced at $464 found 1 day ago
Fri, Sep 12 - Wed, Sep 17
COU
Columbia
TYS
Knoxville
$473 Roundtrip, found 1 day ago
$473
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Sep 12 from Columbia to Knoxville, returning Wed, Sep 17, priced at $473 found 1 day ago
Thu, Sep 11 - Thu, Sep 18
COU
Columbia
TYS
Knoxville
$478 Roundtrip, found 1 day ago
$478
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Sep 11 from Columbia to Knoxville, returning Thu, Sep 18, priced at $478 found 1 day ago
Sun, Sep 14 - Sat, Sep 20
COU
Columbia
TYS
Knoxville
$495 Roundtrip, found 1 day ago
$495
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Sep 14 from Columbia to Knoxville, returning Sat, Sep 20, priced at $495 found 1 day ago
Fri, Sep 12 - Wed, Sep 17
COU
Columbia
TYS
Knoxville
$516 Roundtrip, found 1 day ago
$516
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Sep 12 from Columbia to Knoxville, returning Wed, Sep 17, priced at $516 found 1 day ago
Fri, Sep 12 - Wed, Sep 17
COU
Columbia
TYS
Knoxville
$549 Roundtrip, found 1 day ago
$549
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Sep 12 from Columbia to Knoxville, returning Wed, Sep 17, priced at $549 found 1 day ago
Fri, Sep 12 - Wed, Sep 17
COU
Columbia
TYS
Knoxville
$575 Roundtrip, found 1 day ago
$575
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Sep 12 from Columbia to Knoxville, returning Wed, Sep 17, priced at $575 found 1 day ago
Fri, Sep 12 - Wed, Sep 17
COU
Columbia
TYS
Knoxville
$589 Roundtrip, found 1 day ago
$589
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Sep 12 from Columbia to Knoxville, returning Wed, Sep 17, priced at $589 found 1 day ago
Fri, Sep 12 - Wed, Sep 17
COU
Columbia
TYS
Knoxville
$609 Roundtrip, found 1 day ago
$609
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Sep 12 from Columbia to Knoxville, returning Wed, Sep 17, priced at $609 found 1 day ago
Fri, Sep 12 - Wed, Sep 17
COU
Columbia
TYS
Knoxville
$618 Roundtrip, found 1 day ago
$618
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Sep 12 from Columbia to Knoxville, returning Wed, Sep 17, priced at $618 found 1 day ago

Hotel Ideas near McGhee Tyson

Airport Hotels near McGhee Tyson

Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
$145 nightly
The price is $167 total per night from Aug 3 to Aug 4
$167 total
Aug 3 - Aug 4
Total includes taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,012 reviews)
Top notch hotel
"This was a great way to end my vacation, since my flight arrived at a late hour into TYS. It is an easy and straight walk from baggage claim to the Hilton,or they will come get you in their shuttle. The hotel is great. Pool is fun, too, Restaurant and bar on site."

Reviewed on Jul 26, 2025

Hilton Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road, Alcoa, TN
$73 nightly
The price is $87 total per night from Aug 17 to Aug 18
$87 total
Aug 17 - Aug 18
Total includes taxes and fees
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,504 reviews)
"nice new hotel very close to the airport. they picked me up past midnight.. no issues. overall excellent"

Reviewed on Jul 30, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd, Alcoa, TN
$73 nightly
The price is $87 total per night from Aug 17 to Aug 18
$87 total
Aug 17 - Aug 18
Total includes taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,009 reviews)
"The room was nice and clean, and the beds were very comfortable!"

Reviewed on Jul 26, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Knoxville

Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
$145 nightly
The price is $167 total per night from Aug 3 to Aug 4
$167 total
Aug 3 - Aug 4
Total includes taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,012 reviews)
Top notch hotel
"This was a great way to end my vacation, since my flight arrived at a late hour into TYS. It is an easy and straight walk from baggage claim to the Hilton,or they will come get you in their shuttle. The hotel is great. Pool is fun, too, Restaurant and bar on site."

Reviewed on Jul 26, 2025

Hilton Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road, Alcoa, TN
$73 nightly
The price is $87 total per night from Aug 17 to Aug 18
$87 total
Aug 17 - Aug 18
Total includes taxes and fees
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,504 reviews)
"nice new hotel very close to the airport. they picked me up past midnight.. no issues. overall excellent"

Reviewed on Jul 30, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd, Alcoa, TN
$73 nightly
The price is $87 total per night from Aug 17 to Aug 18
$87 total
Aug 17 - Aug 18
Total includes taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,009 reviews)
"The room was nice and clean, and the beds were very comfortable!"

Reviewed on Jul 26, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Knoxville Hotels With Airport Transportation

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road, Alcoa, TN
$73 nightly
The price is $87 total per night from Aug 17 to Aug 18
$87 total
Aug 17 - Aug 18
Total includes taxes and fees
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,504 reviews)
"nice new hotel very close to the airport. they picked me up past midnight.. no issues. overall excellent"

Reviewed on Jul 30, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
USA Inn

USA Inn

3 out of 5
Alcoa Hwy, 2962, Alcoa, TN
$59 nightly
The price is $70 total per night from Jul 31 to Aug 1
$70 total
Jul 31 - Aug 1
Total includes taxes and fees
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (707 reviews)
Not a good stay
"Upon arrival, no one was tending to the front desk. Another customer walked in and stated he believes they went to the airport. The room smelled clean but the sink had red toothpaste in it from a previous customer. I killed 2 water bugs inside the room and the bed was hard and lumpy"

Reviewed on May 17, 2025

USA Inn
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd, Alcoa, TN
$73 nightly
The price is $87 total per night from Aug 17 to Aug 18
$87 total
Aug 17 - Aug 18
Total includes taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,009 reviews)
"The room was nice and clean, and the beds were very comfortable!"

Reviewed on Jul 26, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Knoxville Hotels

USA Inn

USA Inn

3 out of 5
Alcoa Hwy, 2962, Alcoa, TN
$59 nightly
The price is $70 total per night from Jul 31 to Aug 1
$70 total
Jul 31 - Aug 1
Total includes taxes and fees
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (707 reviews)
Not a good stay
"Upon arrival, no one was tending to the front desk. Another customer walked in and stated he believes they went to the airport. The room smelled clean but the sink had red toothpaste in it from a previous customer. I killed 2 water bugs inside the room and the bed was hard and lumpy"

Reviewed on May 17, 2025

USA Inn
Candlewood Suites Knoxville Airport-Alcoa by IHG

Candlewood Suites Knoxville Airport-Alcoa by IHG

2.5 out of 5
176 Cusick Road, Alcoa, TN
$88 nightly
The price is $105 total per night from Aug 3 to Aug 4
$105 total
Aug 3 - Aug 4
Total includes taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Meigs Falls and Palace Theater ...
8.4/10 Very Good! (559 reviews)
"Ĥhhhhhhhh"

Reviewed on Jul 27, 2025

Candlewood Suites Knoxville Airport-Alcoa by IHG
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd, Alcoa, TN
$73 nightly
The price is $87 total per night from Aug 17 to Aug 18
$87 total
Aug 17 - Aug 18
Total includes taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,009 reviews)
"The room was nice and clean, and the beds were very comfortable!"

Reviewed on Jul 26, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Knoxville

Comfort Suites Knoxville Airport

Comfort Suites Knoxville Airport

2.5 out of 5
140 Cusick Rd, Alcoa, TN
$78 nightly
The price is $92 total per night from Aug 17 to Aug 18
$92 total
Aug 17 - Aug 18
Total includes taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (713 reviews)
"Transportation"

Reviewed on Jul 12, 2025

Comfort Suites Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd, Alcoa, TN
$73 nightly
The price is $87 total per night from Aug 17 to Aug 18
$87 total
Aug 17 - Aug 18
Total includes taxes and fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,009 reviews)
"The room was nice and clean, and the beds were very comfortable!"

Reviewed on Jul 26, 2025

Best Western Knoxville Airport/Alcoa
La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road, Alcoa, TN
$73 nightly
The price is $87 total per night from Aug 17 to Aug 18
$87 total
Aug 17 - Aug 18
Total includes taxes and fees
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,504 reviews)
"nice new hotel very close to the airport. they picked me up past midnight.. no issues. overall excellent"

Reviewed on Jul 30, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

COU to TYS Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

Are there non-stop flights from Columbia Regional Airport to Knoxville Airport?
If you're thinking of flying from Columbia Regional Airport to McGhee Tyson Airport (TYS), get set to change planes. American Airlines, Qatar Airways and Qantas service this route with just one stopover. Use the layover to give your legs a stretch and get a bite to eat.
What is the shortest flight from COU to Knoxville Airport?
The fastest you can fly from Columbia Regional Airport (COU) to McGhee Tyson Airport (TYS) is 3 hours and 29 minutes. Slip a few things into your hand luggage to keep you out of mischief, like that new best-seller or your travel journal.
How many hours flight from COU to Knoxville Airport?
Make yourself comfortable, because the average journey from COU to McGhee Tyson Airport (TYS) is 3 hours and 39 minutes. Watch a few movies, finally finish that book ... There's plenty of time to rest and relax.
What airlines have the most flights from Columbia Regional Airport to Knoxville Airport?
At the moment, there aren't any direct flights between Columbia and Knoxville. However, you will be able to book a flight with at least one stop. It's not all bad — use the break to get the blood moving again or sit down for a nice coffee!

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.