$303 Cheap flight deals from Tampa (TPA) to Panama City (PTY)

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This Weekend's Flight Deals from Tampa to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Nov 15 - Mon, Mar 1
TPA
Tampa Intl.
PTY
Tocumen Intl.
$792 Roundtrip, found 5 days ago
$792
Roundtrip
found 5 days ago
Select United flight, departing Sun, Nov 15 from Tampa Intl. to Tocumen Intl., returning Mon, Mar 1, priced at $792 found 5 days ago

Airfares from $303 One Way, $609 Round Trip from Tampa to Panama City

Prices starting at $609 for return flights and $303 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Sep 8 - Wed, Sep 15
SRQ
Sarasota
PTY
Panama City
$609 Roundtrip, found 5 days ago
$609
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Sep 8 from Sarasota to Panama City, returning Wed, Sep 15, priced at $609 found 5 days ago
Wed, Sep 8 - Wed, Sep 15
SRQ
Sarasota
PTY
Panama City
$618 Roundtrip, found 5 days ago
$618
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Sep 8 from Sarasota to Panama City, returning Wed, Sep 15, priced at $618 found 5 days ago
Wed, Sep 8 - Wed, Sep 15
SRQ
Sarasota
PTY
Panama City
$627 Roundtrip, found 5 days ago
$627
Roundtrip
found 5 days ago
Select Delta flight, departing Wed, Sep 8 from Sarasota to Panama City, returning Wed, Sep 15, priced at $627 found 5 days ago
Wed, Sep 8 - Wed, Sep 15
SRQ
Sarasota
PTY
Panama City
$666 Roundtrip, found 5 days ago
$666
Roundtrip
found 5 days ago
Select American Airlines flight, departing Wed, Sep 8 from Sarasota to Panama City, returning Wed, Sep 15, priced at $666 found 5 days ago
Mon, Feb 8 - Sun, Mar 7
TPA
Tampa
PTY
Panama City
$668 Roundtrip, found 5 days ago
$668
Roundtrip
found 5 days ago
Select avianca flight, departing Mon, Feb 8 from Tampa to Panama City, returning Sun, Mar 7, priced at $668 found 5 days ago

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
Megapolis Hotel Panamá
4.5-star property

Megapolis Hotel Panamá

8.6/10 Excellent! (1,803 reviews)

Dec 24 - Dec 27

3 night stay

Orlando (MCO) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $1,714, price is now $1,113 per person
$1,113
per person
found 1 day ago
Hotel fabuloso,vistas espectaculares,personal bien bien atento siempre dispuestos a ayudar para lo que sea,seguridad en el hotel buenísima sobre todo para subir a la habitacion,buenos restaurantes comida variada el desayuno increíble tremenda atencion es primera vez que visito un hotel de esta categoría con tan buena calidad,sigan así tendrán muchos huéspedes que repetirán la visita como yo

Reviewed on Nov 8, 2026

Central Hotel Panama Casco Viejo
4.0-star property

Central Hotel Panama Casco Viejo

9.2/10 Wonderful! (1,015 reviews)

Dec 24 - Dec 27

3 night stay

Orlando (MCO) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $2,487, price is now $1,372 per person
$1,372
per person
found 1 day ago
Beautiful historic hotel with very clean rooms and great wifi. Mini fridge, safe, bathrobes. Free welcome drink. Perfect location!

Reviewed on Nov 6, 2026

American Trade Hotel
4.5-star property

American Trade Hotel

9.4/10 Exceptional! (820 reviews)

Dec 19 - Dec 24

5 night stay

Orlando (MCO) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $1,763, price is now $1,352 per person
$1,352
per person
found 24 hours ago
Very clean and nice staff

Reviewed on Nov 1, 2026

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More About Flying To Panama City from Tampa

Route Information for Flights from Tampa to Panama City

Origin Airport IATA Code
TPA
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Tampa to Panama City

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Frequently asked questions

Are there non-stop flights from Tampa to Panama City?
Get your passport ready, because Copa Airlines will fly you directly from Tampa to Panama City. Book your plane ticket now and enjoy a stress-free, nonstop flight.
What is the shortest flight from Tampa to Panama City?
Getting from Tampa Airport to Panama Airport will take a minimum of 3 hours and 50 minutes. Enjoy a wine and watch a flick or two — it's a golden opportunity to chill out.
What airlines fly from Tampa to Panama City most frequently?
If you want the airline with the most flights from Tampa, FL (TPA-Tampa Intl.) to Tocumen Intl. Airport (PTY), buckle up and take off with Copa Airlines. This airline offers 17 flights per month along this route.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.