$205 Cheap flight deals from Tampa (TPA) to Panama City (PTY)

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This Weekend's Flight Deals from Tampa to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Dec 21 - Sun, Dec 28
TPA
Tampa Intl.
PTY
Tocumen Intl.
$608 Roundtrip, found 6 hours ago
$608
Roundtrip
found 6 hours ago
Select avianca flight, departing Sun, Dec 21 from Tampa Intl. to Tocumen Intl., returning Sun, Dec 28, priced at $608 found 6 hours ago

Airfares from $205 One Way, $431 Round Trip from Tampa to Panama City

Prices starting at $431 for return flights and $205 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Apr 3 - Sun, Apr 5
TPA
Tampa
PTY
Panama City
$431 Roundtrip, found 2 days ago
$431
Roundtrip
found 2 days ago
Select Copa flight, departing Fri, Apr 3 from Tampa to Panama City, returning Sun, Apr 5, priced at $431 found 2 days ago
Fri, Feb 20 - Sun, Feb 22
TPA
Tampa
PTY
Panama City
$431 Roundtrip, found 2 days ago
$431
Roundtrip
found 2 days ago
Select Copa flight, departing Fri, Feb 20 from Tampa to Panama City, returning Sun, Feb 22, priced at $431 found 2 days ago
Wed, May 6 - Wed, May 13
TPA
Tampa
PTY
Panama City
$434 Roundtrip, found 4 days ago
$434
Roundtrip
found 4 days ago
Select United flight, departing Wed, May 6 from Tampa to Panama City, returning Wed, May 13, priced at $434 found 4 days ago
Fri, Apr 3 - Sun, Apr 5
TPA
Tampa
PTY
Panama City
$435 Roundtrip, found 2 days ago
$435
Roundtrip
found 2 days ago
Select United flight, departing Fri, Apr 3 from Tampa to Panama City, returning Sun, Apr 5, priced at $435 found 2 days ago
Fri, Apr 3 - Sun, Apr 5
TPA
Tampa
PTY
Panama City
$441 Roundtrip, found 2 days ago
$441
Roundtrip
found 2 days ago
Select Copa flight, departing Fri, Apr 3 from Tampa to Panama City, returning Sun, Apr 5, priced at $441 found 2 days ago

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
MARINN PLACE Financial District
3.5-star property

MARINN PLACE Financial District

9.2/10 Wonderful! (298 reviews)

Feb 2 - Feb 6

4 night stay

Orlando (MCO) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $1,015, price is now $658 per person
$658
per person
found 1 day ago
Only small issue, the black out curtain was misaligned. I did an adjustment.

Reviewed on Dec 16, 2024

Central Hotel Panama Casco Viejo
4.0-star property

Central Hotel Panama Casco Viejo

9/10 Wonderful! (1,002 reviews)

Feb 2 - Feb 6

4 night stay

Orlando (MCO) to Panama City (PTY)

Copa • Roundtrip • Coach
Save 100% on your flight
Price was $1,675, price is now $1,102 per person
$1,102
per person
found 1 day ago
Kimberly at the Front Desk was wonderful!

Reviewed on Jun 8, 2025

Megapolis Hotel Panamá
4.5-star property

Megapolis Hotel Panamá

8.4/10 Very Good! (1,204 reviews)

Feb 2 - Feb 6

4 night stay

Orlando (MCO) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $1,185, price is now $836 per person
$836
per person
found 1 day ago
Room was very clean, breakfast was great.Easy check in.

Reviewed on Nov 16, 2025

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More About Flying To Panama City from Tampa

Route Information for Flights from Tampa to Panama City

Origin Airport IATA Code
TPA
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Tampa to Panama City

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Find Low Prices in One Place

Booking a trip from Tampa to Panama City has never been easier. Not only will you find great deals on flights, we offer bargains on cruises, car rentals, top-notch hotels, and more. You can also research and add local activities in Panama City to your flight or hotel reservation to keep the kids happy and active.

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Use our mobile app for your iPhone, iPad, or Android phone—or our mobile website m.orbitz.com—to find bargains on flights from Tampa to Panama City wherever you are. Book your cheap Tampa to Panama City flights and a hotel room too—even at the last minute. Orbitz also makes your life easier with free alerts that are sent to your mobile phone or email about delays to your upcoming flights from Tampa to Panama City.

Don’t Miss out on Miles

Accumulate frequent flyer miles or points on your Tampa to Panama City flights. It’s as simple as entering your frequent flyer number when you’re making your flight reservation on Orbitz to rack up miles on qualified flights from Tampa to Panama City. You can save your frequent flyer numbers in your Orbitz account to save time during your next flight booking.

Frequently asked questions

Are there non-stop flights from Tampa to Panama City?
Get your passport ready, because Copa Airlines will fly you directly from Tampa to Panama City. Book your plane ticket now and enjoy a stress-free, nonstop flight.
What is the shortest flight from Tampa to Panama City?
Getting from Tampa Airport to Panama Airport will take a minimum of 3 hours and 50 minutes. Enjoy a wine and watch a flick or two — it's a golden opportunity to chill out.
What airlines fly from Tampa to Panama City most frequently?
If you want the airline with the most flights from Tampa, FL (TPA-Tampa Intl.) to Tocumen Intl. Airport (PTY), buckle up and take off with Copa Airlines. This airline offers 17 flights per month along this route.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.