
$192 Cheap flight deals from Syracuse (SYR) to Des Moines (SEA)
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This Weekend's Flight Deals from Syracuse to Des Moines
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $192 One Way, $335 Round Trip from Syracuse to Des Moines
Prices starting at $335 for return flights and $192 for one-way flights to Des Moines were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Des Moines economy flight packages

Sleep Inn - SeaTac Airport
Mar 30 - Apr 3
Syracuse (SYR) to Seattle (SEA)
Seattle (SEA) to Syracuse (SYR)
Reviewed on Oct 11, 2025

The Edgewater Hotel
Mar 30 - Apr 3
Syracuse (SYR) to Seattle (SEA)
Seattle (SEA) to Syracuse (SYR)
Reviewed on Aug 4, 2025

Lotte Hotel Seattle
Mar 30 - Apr 3
Syracuse (SYR) to Seattle (SEA)
Seattle (SEA) to Syracuse (SYR)
Reviewed on Feb 16, 2026
More About Flying To Des Moines from Syracuse
Route Information for Flights from Syracuse to Des Moines
Origin Airport IATA Code | SYR |
|---|---|
Destination Airport IATA Code | SEA |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Syracuse to Des Moines
When you’re ready to take your next trip, get the most affordable prices on flights from Syracuse to Des Moines with Orbitz! The guaranteed low prices and cutting-edge mobile tools on Orbits make it easy for you to plan your next great vacation.
Keep Up With Sudden Flight Changes
As any traveler knows, air travel can suddenly be temporarily halted due to service disruptions. Along with offering the best fares for flights from Syracuse to Des Moines, Orbitz also offers free mobile phone and email alerts that help you keep up with sudden changes to your flight plans. Choose from email, text, or voice message alerts.
Get Great Prices for Syracuse to Des Moines Flights
Orbitz features both an Android app and an iPhone app to give you the lowest prices for Syracuse to Des Moines flights. Use these mobile apps to get updates on your flight, the details of your itinerary, and to learn about available hotel deals in the area.
Fly for Less and Earn Miles
Did you know you can earn miles and points for your frequent flyer program with Orbitz? To do this with specific flights from Syracuse to Des Moines, enter your frequent flyer account number when you book your ticket online. For even more convenience, keep a record of your loyalty travel program numbers directly with Orbitz by storing them in your account profile. This way, you can add your account numbers to your next reservation for Syracuse to Des Moines flights automatically without the annoying hassle of having to look them up.
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Des Moines Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.


