No, unfortunately. You'll need to change planes if you want to fly from Des Moines, IA Airport (DSM-Des Moines Intl.) to Daytona Beach, FL Airport (DAB-Daytona Beach Intl.). Various companies service this route with just one stopover, including Delta Air Lines, American Airlines and KLM.
From Des Moines, the unique sights and sounds of Daytona Beach are at least 3 hours and 17 minutes away. Secure your favorite seat, or maybe even one with more legroom, and fly to your destination in pure comfort.
|Origin Airport IATA Code||DSM|
|Destination Airport IATA Code||DAB|
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^Savings based on all package bookings with Flight + Hotel made on Orbitz.com from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.