
$156 Cheap flight deals from Des Moines (DSM) to Cleveland (HOU)
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This Weekend's Flight Deals from Des Moines to Cleveland
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $156 One Way, $174 Round Trip from Des Moines to Cleveland
Prices starting at $174 for return flights and $156 for one-way flights to Cleveland were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Cleveland economy flight packages

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Feb 27 - Mar 1
Des Moines (DSM) to Houston (IAH)
Reviewed on Dec 1, 2025

Holiday Inn Houston Downtown by IHG
Feb 27 - Mar 1
Des Moines (DSM) to Houston (IAH)
Reviewed on Jun 17, 2025

Hilton Houston Post Oak by the Galleria
Feb 27 - Mar 1
Des Moines (DSM) to Houston (IAH)
Reviewed on Aug 19, 2025
More About Flying To Cleveland from Des Moines
Route Information for Flights from Des Moines to Cleveland
Origin Airport IATA Code | DSM |
|---|---|
Destination Airport IATA Code | HOU |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Des Moines to Cleveland
Orbitz combines guaranteed low prices with cutting-edge mobile tools for travel from Des Moines to Cleveland to give you a travel experience that is second to none.
Bargain Travel at Your Fingertips
Orbitz provides the cheapest fares from Des Moines to Cleveland. When reserving your flight you can mix and match a range of low cost airlines for you departing and returning domestic or international flights. This way you can travel on a budget while selecting the flights that suit your schedule.
Modern Tools for Fast-Paced Travel
Orbitz makes use of the latest technology to ensure that you are always kept up-to-date on the status of your Des Moines to Cleveland flights. Through easy-to-use mobile Android and iPhone apps you can book low cost flights from Des Moines to Cleveland and choose a range of cheap hotels to stay in.
Enjoy Stress-Free Travel with Flight Alerts
Once you have booked your flights from Des Moines to Cleveland on Orbitz you will always be kept informed of any changes to your flight. When you opt into Orbitz’s free email and SMS alerts on your Des Moines to Cleveland flights you can ask Orbitz to send the flight details to up to 6 other contacts, so keeping your family and business team informed is a cinch.
Frequent Flyer Program
For loyal Orbitz customers who fly from Des Moines to Cleveland the chance to join our frequent flyer program is an added bonus. Simply log-on to your online account and input your frequent flyer number for future flights.
Flights from Des Moines
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Des Moines Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

