$131 Cheap flight deals from Des Moines (DSM) to Santa Rosa (SFO)

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This Weekend's Flight Deals from Des Moines to Santa Rosa

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jul 26 - Wed, Aug 13
DSM
Des Moines Intl.
SFO
San Francisco Intl.
$526 Roundtrip, found 1 hour ago
$526
Roundtrip
found 1 hour ago
Select Delta flight, departing Sat, Jul 26 from Des Moines Intl. to San Francisco Intl., returning Wed, Aug 13, priced at $526 found 1 hour ago

Airfares from $131 One Way, $269 Round Trip from Des Moines to Santa Rosa

Prices starting at $269 for return flights and $131 for one-way flights to Santa Rosa were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Aug 22 - Sun, Aug 31
DSM
Des Moines
SFO
San Francisco
$269 Roundtrip, found 6 days ago
$269
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Fri, Aug 22 from Des Moines to San Francisco, returning Sun, Aug 31, priced at $269 found 6 days ago
Fri, Oct 24 - Mon, Oct 27
DSM
Des Moines
SFO
San Francisco
$286 Roundtrip, found 6 days ago
$286
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Fri, Oct 24 from Des Moines to San Francisco, returning Mon, Oct 27, priced at $286 found 6 days ago
Mon, Sep 15 - Sat, Sep 20
DSM
Des Moines
SFO
San Francisco
$289 Roundtrip, found 5 days ago
$289
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Mon, Sep 15 from Des Moines to San Francisco, returning Sat, Sep 20, priced at $289 found 5 days ago
Thu, Sep 4 - Sun, Sep 7
DSM
Des Moines
SFO
San Francisco
$290 Roundtrip, found 6 days ago
$290
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Thu, Sep 4 from Des Moines to San Francisco, returning Sun, Sep 7, priced at $290 found 6 days ago
Tue, Oct 14 - Sat, Oct 18
DSM
Des Moines
SFO
San Francisco
$313 Roundtrip, found 3 hours ago
$313
Roundtrip
found 3 hours ago
Select United flight, departing Tue, Oct 14 from Des Moines to San Francisco, returning Sat, Oct 18, priced at $313 found 3 hours ago

Santa Rosa economy flight packages

Price found within the past 48 hours. Click for updated prices.
Bay Landing San Francisco Airport Hotel
3.0-star property

Bay Landing San Francisco Airport Hotel

9/10 Wonderful! (4,394 reviews)

Aug 29 - Sep 2

4 night stay

Des Moines (DSM) to San Francisco (SFO)

Frontier Airlines • Non-stop • Coach

San Francisco (SFO) to Des Moines (DSM)

United • Non-stop • Coach
per person
found 9 hours ago
Very nice view , nice people

Reviewed on Jul 7, 2025

The Donatello
3.5-star property

The Donatello

9.2/10 Wonderful! (1,000 reviews)

Aug 29 - Sep 2

4 night stay

Des Moines (DSM) to San Francisco (SFO)

Frontier Airlines • Non-stop • Coach

San Francisco (SFO) to Des Moines (DSM)

United • Non-stop • Coach
per person
found 9 hours ago
The Donatello is a favorite stay for us when we visit San Francisco … it is conveniently located. It’s an easy walk from the BART/Muni station. The rooms are spacious and clean. But the reason why we keep coming back and back is because of the outstanding staff. They are friendly and helpful. They go out of their way to accommodate and assist.

Reviewed on May 25, 2025

Marriott San Francisco Fisherman's Wharf
4.0-star property

Marriott San Francisco Fisherman's Wharf

8.8/10 Excellent! (1,004 reviews)

Aug 29 - Sep 2

4 night stay

Des Moines (DSM) to San Francisco (SFO)

Frontier Airlines • Non-stop • Coach

San Francisco (SFO) to Des Moines (DSM)

United • Non-stop • Coach
per person
found 9 hours ago
The location was great-close to the Fisherman Wharf area, restaurants and shopping. We took the public transportation (BART and bus) and the stop was right in front of the hotel. The hotel is very clean and best of all, we had a great experience with each staff member we met. I would definitely recommend this place and we will book this place if we ever come back to San Francisco!

Reviewed on Jul 16, 2025

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More About Flying To Santa Rosa from Des Moines

Route Information for Flights from Des Moines to Santa Rosa

Origin Airport IATA Code
DSM
Destination Airport IATA Code
SFO
Distance
1546 mi
Direct Flight Airlines
United Airlines
Earliest Flight Arrival
12:24AM UTC
Latest Flight Arrival
2:16AM UTC

Des Moines to Santa Rosa

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Frequently asked questions

What is the shortest flight from Des Moines to Santa Rosa?
The shortest flight time from Des Moines, IA (DSM-Des Moines Intl.) to SFO is around 4 hours and 30 minutes. Grab a refreshment from the cabin crew, hone your travel itinerary or get to know your neighbors — you'll have enough time on this medium-haul journey.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.