$202 Cheap flight deals from Panama City (PTY) to Mexico City (MEX)

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This Weekend's Flight Deals from Panama City to Mexico City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jul 5 - Tue, Aug 12
PTY
Tocumen Intl.
MEX
Mexico City Intl.
$343 Roundtrip, found 1 hour ago
$343
Roundtrip
found 1 hour ago
Select Aeromexico flight, departing Sat, Jul 5 from Tocumen Intl. to Mexico City Intl., returning Tue, Aug 12, priced at $343 found 1 hour ago

Airfares from $202 One Way, $341 Round Trip from Panama City to Mexico City

Prices starting at $341 for return flights and $202 for one-way flights to Mexico City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Dec 3 - Tue, Dec 23
PTY
Panama City
MEX
Mexico City
$341 Roundtrip, found 1 day ago
$341
Roundtrip
found 1 day ago
Select Copa flight, departing Wed, Dec 3 from Panama City to Mexico City, returning Tue, Dec 23, priced at $341 found 1 day ago
Mon, Dec 15 - Tue, Dec 30
PTY
Panama City
MEX
Mexico City
$342 Roundtrip, found 1 day ago
$342
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Mon, Dec 15 from Panama City to Mexico City, returning Tue, Dec 30, priced at $342 found 1 day ago
Fri, Sep 19 - Sat, Sep 27
PTY
Panama City
MEX
Mexico City
$342 Roundtrip, found 15 hours ago
$342
Roundtrip
found 15 hours ago
Select Copa flight, departing Fri, Sep 19 from Panama City to Mexico City, returning Sat, Sep 27, priced at $342 found 15 hours ago
Fri, Jul 18 - Mon, Jul 28
PTY
Panama City
MEX
Mexico City
$352 Roundtrip, found 1 day ago
$352
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Jul 18 from Panama City to Mexico City, returning Mon, Jul 28, priced at $352 found 1 day ago
Fri, Sep 19 - Sat, Sep 27
PTY
Panama City
MEX
Mexico City
$353 Roundtrip, found 15 hours ago
$353
Roundtrip
found 15 hours ago
Select Copa flight, departing Fri, Sep 19 from Panama City to Mexico City, returning Sat, Sep 27, priced at $353 found 15 hours ago

Mexico City economy flight packages

Price found within the past 48 hours. Click for updated prices.
Hive Mexico City By Ghotels
3.0-star property

Hive Mexico City By Ghotels

8.8/10 Excellent! (867 reviews)

Aug 7 - Aug 11

4 night stay

Panama City (PTY) to Mexico City (MEX)

Aeromexico • Roundtrip • Coach
Save 100% on your flight
per person
found 1 day ago
Great hotel. Great location. All staff members were very helpful and kind.

Reviewed on Nov 1, 2016

Casa de la Luz Hotel Boutique
4.0-star property

Casa de la Luz Hotel Boutique

9.6/10 Exceptional! (364 reviews)

Aug 7 - Aug 11

4 night stay

Panama City (PTY) to Mexico City (MEX)

Aeromexico • Roundtrip • Coach
Save 100% on your flight
per person
found 1 day ago
The hotel is a diamond within a scruffy neighborhood. A wonderful oasis within the historic core of Mexico City. It's sited on a quarter-block park which removes it a touch from the roar of traffic. Staff is fantastic and the included breakfast is unparalleled.

Reviewed on Feb 14, 2025

Casa Decu
4.0-star property

Casa Decu

9.4/10 Exceptional! (719 reviews)

Aug 7 - Aug 11

4 night stay

Panama City (PTY) to Mexico City (MEX)

Aeromexico • Roundtrip • Coach
Save 100% on your flight
per person
found 1 day ago
Great boutique hotel located in a cute neighborhood in La Condensa. Staff hospitality was amazing with provided great restaurant recommendation and quick response. Accessible to cute cafes and delicious restaurants…all within walking distance. I would definitely recommend this hotel.

Reviewed on Sep 10, 2023

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More About Flying To Mexico City from Panama City

Route Information for Flights from Panama City to Mexico City

Origin Airport IATA Code
PTY
Destination Airport IATA Code
MEX
Distance
1498 mi
Direct Flight Airlines
Emirates, Copa Airlines, Aeromexico
Earliest Flight Arrival
5:10PM UTC
Latest Flight Arrival
6:00AM UTC

Panama City to Mexico City

It has never been easier to find cheap Panama City to Mexico City flights. Orbitz has some of the best deals around to save you more money on your flight, hotel, and vacation package for the trip you have been waiting for.

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Stay on top of the latest updates for flights from Panama City to Mexico City. We send you free email and mobile alerts to keep you informed about delays to Panama City to Mexico City flights.

Frequently asked questions

Are there non-stop flights from Panama City to Mexico City?
There most certainly is. Copa Airlines offers direct flights from PTY to MEX, which makes going from Panama City to Mexico City a cinch.
What is the shortest flight from Panama City to Mexico City?
The quickest flight time from Tocumen Intl. Airport (PTY) to MEX is around 3 hours and 47 minutes. Order a wine from the drink cart, write in your travel journal or make friends with your seat mate --- you'll have the time on this medium-haul journey.
What airlines fly from Panama City to Mexico City most frequently?
Copa Airlines is the most frequent airline servicing the Panama City to Mexico City route. You can select from 152 flights every month with this carrier.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.