
$33 Cheap flight deals from Los Angeles (QLA) to Des Moines (SEA)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
This Weekend's Flight Deals from Los Angeles to Des Moines
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $33 One Way, $66 Round Trip from Los Angeles to Des Moines
Prices starting at $66 for return flights and $33 for one-way flights to Des Moines were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Des Moines economy flight packages

Sleep Inn - SeaTac Airport
Mar 20 - Mar 23
Burbank (BUR) to Seattle (SEA)
Reviewed on Oct 11, 2025

1 Hotel Seattle
Mar 27 - Mar 31
Burbank (BUR) to Seattle (SEA)
Reviewed on May 27, 2025

Mayflower Park Hotel
Mar 20 - Mar 23
Burbank (BUR) to Seattle (SEA)
Reviewed on Nov 13, 2025
Des Moines packages with premium economy flights


More About Flying To Des Moines from Los Angeles
Route Information for Flights from Los Angeles to Des Moines
Origin Airport IATA Code | QLA |
|---|---|
Destination Airport IATA Code | SEA |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Los Angeles to Des Moines
The perfect trip begins with Orbitz. From booking your flights from Los Angeles to Des Moines to finding the best hotels, Orbitz has got it covered.
Stress-free Searching
With an easy to use system, Orbitz takes the stress and expense out of travel. Not only does Orbitz match your Los Angeles to Des Moines flights to your ideal hotel, the Display Matrix shows your deals and discounts, including free nights and other savings.
Be One Step Ahead
Need to know what is going on at the airport before you get there? With Orbitz’s free alerts service, you can quickly find out about any booking changes, or flight from Los Angeles to Des Moines disruptions, saving you hours of wasted time. And if you are being picked up at the airport after your Los Angeles to Des Moines flights, have alerts sent straight to your contact’s mobile phone or email.
Cutting-Edge Mobile Tools
Find the best price on flights from Los Angeles to Des Moines with Orbitz’s mobile apps for iPhone and Android. Use m.orbitz.com on your mobile browser to check your gate, baggage allowance and delays, or find exclusive deals on hotels only available to mobile users.
We Work, you Rest and Play
Not only does booking with us ensure guaranteed low prices, but Orbitz does the hard work, leaving you to relax. Just tell us what you want, from Los Angeles to Des Moines flights, to great deals on hotels and car rental, and activities and tours, and we will do all the rest.
Flights from Los Angeles
- Los Angeles to Chicago
- Los Angeles to New York
- Los Angeles to Dallas
- Los Angeles to Houston
- Los Angeles to Kansas City
- Los Angeles to Orlando
- Los Angeles to San Francisco
- Los Angeles to Toronto
- Los Angeles to Rome
- Los Angeles to Detroit
- Los Angeles to London
- Los Angeles to Los Angeles
- Los Angeles to New Orleans
- Los Angeles to Phoenix
- Los Angeles to Washington
- Los Angeles to Sacramento
- Los Angeles to Montreal
- Los Angeles to Seattle
- Los Angeles to St. Louis
- Los Angeles to Edmonton
Des Moines Airports
More Destinations
- Flights from Avoca to SeaTac
- Flights from Honolulu to SeaTac
- Flights from Austin to SeaTac
- Flights from Cleveland to SeaTac
- Flights from Minneapolis - St. Paul to SeaTac
- Flights from Santa Fe to SeaTac
- Flights from Sacramento to SeaTac
- Flights from Hailey to SeaTac
- Flights from Lewiston to SeaTac
- Flights from Newark to SeaTac
- Flights from Bentonville - Fayetteville to SeaTac
- Flights from Casper to SeaTac
- Flights from College Park to SeaTac
- Flights from Chicago to Seattle
- Flights from Dallas to Seattle
- Flights from Las Vegas to Seattle
- Flights from Los Angeles to Seattle
- Flights from New York to Seattle
- Flights from Phoenix to Seattle
- Flights from San Francisco to Seattle
- Flights from Albuquerque (ABQ) to Seattle (SEA)
- Flights from Anchorage (ANC) to Seattle (SEA)
- Flights from Atlanta (ATL) to Seattle (SEA)
- Flights from Austin (AUS) to Seattle (SEA)
- Flights from Hartford (BDL) to Seattle (SEA)
- Flights from Billings (BIL) to Seattle (SEA)
- Flights from Nashville (BNA) to Seattle (SEA)
- Flights from Boise (BOI) to Seattle (SEA)
- Flights from Boston (BOS) to Seattle (SEA)
- Flights from Buffalo (BUF) to Seattle (SEA)
- Flights from Burbank (BUR) to Seattle (SEA)
- Flights from Baltimore (BWI) to Seattle (SEA)
- Flights from Bozeman (BZN) to Seattle (SEA)
- Flights from Charleston (CHS) to Seattle (SEA)
- Flights from Charlotte (CLT) to Seattle (SEA)
- Flights from Columbus (CMH) to Seattle (SEA)
- Flights from Cancun (CUN) to Seattle (SEA)
- Flights from Cincinnati (CVG) to Seattle (SEA)
- Flights from Washington (DCA) to Seattle (SEA)
- Flights from Denver (DEN) to Seattle (SEA)
- Flights from Dallas (DFW) to Seattle (SEA)
- Flights from Des Moines (DSM) to Seattle (SEA)
- Flights from Detroit (DTW) to Seattle (SEA)
- Flights from Eugene (EUG) to Seattle (SEA)
- Flights from Newark Liberty Intl. Airport (EWR) to Seattle (SEA)
- Flights from Fresno (FAT) to Seattle (SEA)
- Flights from Guadalajara (GDL) to Seattle (SEA)
- Flights from Spokane (GEG) to Seattle (SEA)
- Flights from Tokyo (HND) to Seattle (SEA)
- Flights from Honolulu (HNL) to Seattle (SEA)
- Flights from Washington (IAD) to Seattle (SEA)
- Flights from Houston (IAH) to Seattle (SEA)
- Flights from Seoul (ICN) to Seattle (SEA)
- Flights from Indianapolis (IND) to Seattle (SEA)
- Flights from Jacksonville (JAX) to Seattle (SEA)
- Flights from New York (JFK) to Seattle (SEA)
- Flights from Las Vegas (LAS) to Seattle (SEA)
- Flights from Los Angeles (LAX) to Seattle (SEA)
- Flights from New York (LGA) to Seattle (SEA)
- Flights from Long Beach (LGB) to Seattle (SEA)
- Flights from Chennai (MAA) to Seattle (SEA)
- Flights from Kansas City (MCI) to Seattle (SEA)
- Flights from Orlando (MCO) to Seattle (SEA)
- Flights from Chicago (MDW) to Seattle (SEA)
- Flights from Memphis (MEM) to Seattle (SEA)
- Flights from Mexico City (MEX) to Seattle (SEA)
- Flights from Medford (MFR) to Seattle (SEA)
- Flights from Miami (MIA) to Seattle (SEA)
- Flights from Milwaukee (MKE) to Seattle (SEA)
- Flights from Manila (MNL) to Seattle (SEA)
- Flights from Missoula (MSO) to Seattle (SEA)
- Flights from Minneapolis (MSP) to Seattle (SEA)
- Flights from Oakland (OAK) to Seattle (SEA)
- Flights from Oklahoma City (OKC) to Seattle (SEA)
- Flights from Ontario (ONT) to Seattle (SEA)
- Flights from Chicago (ORD) to Seattle (SEA)
- Flights from Portland (PDX) to Seattle (SEA)
- Flights from Philadelphia (PHL) to Seattle (SEA)
- Flights from Phoenix (PHX) to Seattle (SEA)
- Flights from Pasco (PSC) to Seattle (SEA)
- Flights from Pullman (PUW) to Seattle (SEA)
- Flights from Shanghai (PVG) to Seattle (SEA)
- Flights from Redding (RDD) to Seattle (SEA)
- Flights from Redmond (RDM) to Seattle (SEA)
- Flights from Raleigh (RDU) to Seattle (SEA)
- Flights from Reno (RNO) to Seattle (SEA)
- Flights from San Diego (SAN) to Seattle (SEA)
- Flights from Santa Barbara (SBA) to Seattle (SEA)
- Flights from San Luis Obispo (SBP) to Seattle (SEA)
- Flights from Santo Domingo (SDQ) to Seattle (SEA)
- Flights from San Francisco (SFO) to Seattle (SEA)
- Flights from San Jose (SJC) to Seattle (SEA)
- Flights from Salt Lake City (SLC) to Seattle (SEA)
- Flights from Sacramento (SMF) to Seattle (SEA)
- Flights from Orange County (SNA) to Seattle (SEA)
- Flights from Seward (SWD) to Seattle (SEA)
- Flights from Tampa (TPA) to Seattle (SEA)
- Flights from Taipei (TPE) to Seattle (SEA)
- Flights from Yakima (YKM) to Seattle (SEA)
- Flights from Vancouver (YVR) to Seattle (SEA)
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.



