$406 Cheap flight deals from Des Moines (DSM) to Quad Cities (MLI)

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Airfares from $406 One Way, Round Trip from Des Moines to Quad Cities

Prices starting at for return flights and $406 for one-way flights to Quad Cities were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

More About Flying To Quad Cities from Des Moines

Route Information for Flights from Des Moines to Quad Cities

Origin Airport IATA Code
DSM
Destination Airport IATA Code
MLI
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Des Moines to Quad Cities

Finding cheap flights from Des Moines to Quad Cities need never be a problem again when you put your faith in Orbitz, the online leader in discounted travel arrangements. You’ll get guaranteed low prices every time you book and be able to choose from a great selection of hotels, flight, cruises, and more.

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You can have total confidence in Orbitz to help you find spectacular deals on Des Moines to Quad Cities flights at bargain prices. We also display quality accommodations at unbelievable rates, leaving you with spare cash for a little extra indulgence in Quad Cities.

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Frequently asked questions

What is the shortest flight from Des Moines to Quad Cities?
If conditions are good and all goes as scheduled, you could be disembarking at Quad City Intl. Airport (MLI) from Des Moines, IA (DSM-Des Moines Intl.) in only 2 hours and 17 minutes. With such a speedy flight time, think about taking carry-on luggage only.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.