$324 Cheap flight deals from Raleigh (RDU) to Panama City (PTY)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Raleigh to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Oct 25 - Fri, Oct 30
RDU
Raleigh - Durham Intl.
PTY
Tocumen Intl.
$827 Roundtrip, found 2 days ago
$827
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Oct 25 from Raleigh - Durham Intl. to Tocumen Intl., returning Fri, Oct 30, priced at $827 found 2 days ago

Airfares from $324 One Way, $685 Round Trip from Raleigh to Panama City

Prices starting at $685 for return flights and $324 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Mar 4 - Thu, Mar 18
RDU
Raleigh
PTY
Panama City
$685 Roundtrip, found 19 hours ago
$685
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Thu, Mar 4 from Raleigh to Panama City, returning Thu, Mar 18, priced at $685 found 19 hours ago
Mon, Mar 8 - Thu, Mar 18
RDU
Raleigh
PTY
Panama City
$690 Roundtrip, found 2 days ago
$690
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Mar 8 from Raleigh to Panama City, returning Thu, Mar 18, priced at $690 found 2 days ago
Thu, Mar 4 - Thu, Mar 18
RDU
Raleigh
PTY
Panama City
$697 Roundtrip, found 19 hours ago
$697
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Thu, Mar 4 from Raleigh to Panama City, returning Thu, Mar 18, priced at $697 found 19 hours ago
Mon, Mar 8 - Thu, Mar 18
RDU
Raleigh
PTY
Panama City
$702 Roundtrip, found 2 days ago
$702
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Mar 8 from Raleigh to Panama City, returning Thu, Mar 18, priced at $702 found 2 days ago
Thu, Mar 11 - Tue, Mar 16
RDU
Raleigh
PTY
Panama City
$704 Roundtrip, found 13 hours ago
$704
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Thu, Mar 11 from Raleigh to Panama City, returning Tue, Mar 16, priced at $704 found 13 hours ago

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
Hotel Casa Panamá
4.0-star property

Hotel Casa Panamá

7.6/10 Good! (758 reviews)

Dec 10 - Dec 15

5 night stay

Raleigh (RDU) to Panama City (PTY)

United • Non-stop roundtrip • Coach
Price was $1,213, price is now $994 per person
$994
per person
found 17 hours ago

Central Hotel Panama Casco Viejo
4.0-star property

Central Hotel Panama Casco Viejo

9/10 Wonderful! (1,006 reviews)

Dec 10 - Dec 15

5 night stay

Raleigh (RDU) to Panama City (PTY)

United • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $2,583, price is now $1,347 per person
$1,347
per person
found 17 hours ago
Property was clean and nice, breakfast was excellent.

Reviewed on Oct 20, 2026

Las Clementinas
3.5-star property

Las Clementinas

9.4/10 Exceptional! (203 reviews)

Dec 10 - Dec 15

5 night stay

Raleigh (RDU) to Panama City (PTY)

United • Non-stop roundtrip • Coach
Price was $1,603, price is now $1,260 per person
$1,260
per person
found 17 hours ago

Don't see what you're looking for?
See all available trips from Raleigh to Panama City
View all trips

More About Flying To Panama City from Raleigh

Route Information for Flights from Raleigh to Panama City

Origin Airport IATA Code
RDU
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Raleigh to Panama City

The best fares for Raleigh to Panama City flights are always found on Orbitz. With superior discounts and the latest innovations in mobile access, your ideal trip starts with Orbitz.

The Easy Way to Plan Travel Cheaply

We provide access to many low-cost vacation packages and travelers can mix and match airlines when scheduling their flights for the best prices and flight times. Finding cheap tickets on flights from Raleigh to Panama City is easy when you make Orbitz your #1 travel planner.

Book Raleigh to Panama City Flights With Mobile Apps

Our iPhone and Android mobile apps can be used to compare and book flights from Raleigh to Panama City. These apps are perfect for checking the status of flights, gate and baggage claims details, car rental rates, and for receiving alerts on special savings that are exclusive to mobile users. Mobile app users can even score great rates when booking hotel rooms. You can compare hotels, virtually view photo galleries, and check out user reviews using the app, as well as find out which ones are closest to you.

Orbitz also offers free travel updates that are sent to your email or mobile phone that notifies you of booking changes, disruptions in service, or delayed flights.

Increase Your Rewards While Enjoying Super Low Rates

Boost your points or miles for your frequent flyer program on certain Raleigh to Panama City flights. Simply provide your frequent flyer information when booking flights from Raleigh to Panama City with Orbitz and get both a low fare and travel rewards. You can enter this information in your Orbitz account profile for easy remembering in future bookings.

Frequently asked questions

What is the shortest flight from Raleigh to Panama City?
The shortest flight time from RDU to Panama Airport is 4 hours and 54 minutes, which gives you loads of time to indulge in a drink or get absorbed in a good movie.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.