$112 Cheap flights to South America
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Top places to visit in South America
Cheap flights to South America from $112 One Way, $332 Round Trip
$332 return flights and $112 one-way flights to South America were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
MCO
Orlando
BOG
Bogotá
$332 Roundtrip, just found
$332
Roundtrip
just found
MCO
Orlando
BOG
Bogotá
$498 Roundtrip, found 4 hours ago
$498
Roundtrip
found 4 hours ago
JFK
New York
UIO
Quito
$504 Roundtrip, found 10 hours ago
$504
Roundtrip
found 10 hours ago
MCO
Orlando
SCL
Santiago
$512 Roundtrip, found 2 days ago
$512
Roundtrip
found 2 days ago
MCO
Orlando
UIO
Quito
$528 Roundtrip, found 1 day ago
$528
Roundtrip
found 1 day ago
MCO
Orlando
GIG
Rio de Janeiro
$530 Roundtrip, found 1 day ago
$530
Roundtrip
found 1 day ago
MCO
Orlando
SDU
Rio de Janeiro
$537 Roundtrip, found 4 hours ago
$537
Roundtrip
found 4 hours ago
JFK
New York
GIG
Rio de Janeiro
$549 Roundtrip, found 1 day ago
$549
Roundtrip
found 1 day ago
JFK
New York
UIO
Quito
$567 Roundtrip, found 4 hours ago
$567
Roundtrip
found 4 hours ago
JFK
New York
BOG
Bogotá
$606 Roundtrip, found 3 days ago
$606
Roundtrip
found 3 days ago
JFK
New York
LIM
Lima
$630 Roundtrip, found 4 hours ago
$630
Roundtrip
found 4 hours ago
JFK
New York
SDU
Rio de Janeiro
$658 Roundtrip, found 1 day ago
$658
Roundtrip
found 1 day ago
Deals For This Weekend's Flights
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| MIA | Bogotá | November 6 to November 14 | $471 |
| MIA | Quito | November 6 to November 9 | $554 |
| JFK | Lima | November 7 to November 20 | $747 |
| LHR | Bogotá | November 6 to November 16 | $1,013 |
| JFK | São Paulo | November 6 to November 10 | $1,074 |
| LHR | São Paulo | November 8 to November 21 | $1,091 |
| LHR | Lima | November 8 to November 29 | $1,141 |
| LHR | Rio de Janeiro | November 8 to November 19 | $1,316 |
| LHR | Quito | November 8 to November 9 | $1,614 |
| BKK | São Paulo | November 8 to November 14 | $1,733 |
| SIN | Bogotá | November 8 to November 22 | $2,030 |
| BKK | Buenos Aires | November 7 to November 13 | $2,145 |
| LHR | Buenos Aires | November 6 to November 22 | $2,210 |
| BKK | Belem | November 7 to November 24 | $2,447 |
| SIN | Santiago | November 7 to November 20 | $2,463 |
Find The Perfect Hotel For After Your Flight
Score Epic South America Accommodation Deals
Padama Hotel
Av. El Olivar 1238 Callao Lima
Fully refundableReserve now, pay when you stay
$26 nightly
The price is $26 total per night from Nov 7 to Nov 8
$26 total
Nov 7 - Nov 8
Stay at this hotel in Callao. Enjoy free WiFi, private hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Plaza ...
Hotel Dorado Plaza Centro Histórico
Carrera 9 31-72 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $66 total per night from Dec 1 to Dec 2
$66 total
Dec 1 - Dec 2
Stay at this hotel in Cartagena. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (542 reviews)
"excelente ubicacion"
Reviewed on Sep 22, 2026
Quito Airport Suites
Conector Alpachaca N8-233 Tababela
$44 nightly
The price is $49 total per night from Nov 7 to Nov 8
$49 total
Nov 7 - Nov 8
Book a stay at this family-friendly guesthouse in Tababela. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Save an average of 15% on thousands of hotels when you're signed in
Altura Suites
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Plaza de Armas and Costanera Center are located ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Our Top South America Apartment Hotels
Altura Suites
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Plaza de Armas and Costanera Center are located ...
Sites Hotel
Carrera 45 No. 5 - 15 Medellín
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $87 total per night from Nov 5 to Nov 6
$87 total
Nov 5 - Nov 6
Book a stay at this business-friendly aparthotel in Medellín. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
Hotel Du Parc
Calle 9 Nº 41 - 36 Medellín Antioquia
Fully refundable
$179 nightly
The price is $179 total per night from Dec 3 to Dec 4
$179 total
Dec 3 - Dec 4
Book a stay at this luxury hotel in Medellín. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the breakfast and the helpful staff in our ...
Save an average of 15% on thousands of hotels when you're signed in
Lancaster House
Paralela Autonorte No 106B - 28 Bogotá Distrito Capital
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $65 total per night from Dec 5 to Dec 6
$65 total
Dec 5 - Dec 6
Book a stay at this spa hotel in Bogotá. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the overall value in ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Score Epic South America Accommodation Deals
Rochester Classic
Esmeralda 542 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $95 total per night from Nov 26 to Nov 27
$95 total
Nov 26 - Nov 27
Book a stay at this business-friendly hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Palermo ...
7.8/10 Good! (428 reviews)
"The property is clean, and very well located for dinning, shopping, cultural life, touristic attractions. It is very important to know, if you decide to rent a car, that the property has NO PARKING available and there is NO STREET PARKING AROUND! There are several parking garages around but they ..."
Reviewed on Sep 12, 2026
Regal Pacific Buenos Aires
25 De Mayo, 764 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $138 total per night from Nov 6 to Nov 7
$138 total
Nov 6 - Nov 7
Book a stay at this luxury hotel in Buenos Aires. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
Concorde Hotel
25 De Mayo 630 Buenos Aires Capital Federal
Stay at this hotel in Buenos Aires. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Obelisco and Palermo Soho are located ...
6.6/10 (300 reviews)
Good located and no expensive hotel in Buenos Aire
"Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city."
Reviewed on Mar 6, 2018
Save an average of 15% on thousands of hotels when you're signed in
Almacruz Hotel y Centro de Convenciones
San Antonio 65 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $80 total per night from Nov 5 to Nov 6
$80 total
Nov 5 - Nov 6
Book a stay at this business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (743 reviews)
"Well place, friendly staff and great environment"
Reviewed on Nov 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in South America
Hotel Las Americas Torre del Mar
Anillo Vial, Sector Cielo Mar, Torre 2 Cartagena Bolivar
$198 nightly
The price is $198 total per night from Nov 7 to Nov 8
$198 total
Nov 7 - Nov 8
Book a stay at this luxury hotel in Cartagena. Enjoy free WiFi, free parking, and 5 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
Agora Suites Self-Service Boutique Hotel
Calle 67B No. 60-67 Bogotá Bogota D.C.
Stay at this hotel in Bogotá. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Popular attractions 93 Park and Movistar Arena are located ...
9/10 Wonderful! (193 reviews)
"Great property but be warned, no one after hours is there to greet you. After hours in my case was 7 pm. Though the next day, the maid was gone and no one there by 3 pm. Ideally you have communicated before on WhatsApp and have both the door code and the room code recorded. If not, assuming you have ..."
Reviewed on Oct 29, 2024
Las Americas Casa de Playa
Anillo Vial Sector Cielo Mar Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$165 nightly
The price is $165 total per night from Nov 17 to Nov 18
$165 total
Nov 17 - Nov 18
Book a stay at this beach hotel in Cartagena. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
Save an average of 15% on thousands of hotels when you're signed in
Hilton Cartagena
Avenida Almirante Brion, El Laguito Cartagena
Fully refundableReserve now, pay when you stay
$196 nightly
The price is $196 total per night from Nov 9 to Nov 10
$196 total
Nov 9 - Nov 10
Book a stay at this luxury resort in Cartagena. Enjoy free parking, 4 outdoor pools, and a full-service spa. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,528 reviews)
Families like: Outdoor pools, waterslide, kids club, playground
Travelers say...
"Very nice hotel one of the best."
Reviewed on Nov 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Need a Car For After Your Flight?
Economy
Chevrolet Spark
Compact
Ford Focus
Midsize
Toyota Corolla
SUV
Jeep Compass
South America
Traveling to South America and need a cheap flight? Orbitz has great deals on flights to South America right now. Plus, we offer big discounts on hotel rooms and car rentals for a great money-saving trip.
Find Low Cost Flights to South America Quickly and Hassle-Free
There are many Internet sites that promise cheap South America flights, but a busy, bargain-minded trip planner needs more than just budget air tickets. Not only does Orbitz offer the best deals for domestic and international air fare, but we also provide the resources and tools to help you plan your flights to South America, book your lodging, and look up key attractions in South America. Our easy search tools and guaranteed low prices let you budget your time and your money so you have more of both to spend on your vacation.
New Apps Make Booking South America Flights Easier Than Ever
You no longer need to be sitting at your computer to find amazing Orbitz sales for flights to South America now we offer cutting-edge mobile tools for many Android and iOS gadgets. These free apps allow you to run a search for discount air fare, look for special vacation packages, or check on your booked South America flights from any location. Some special deals are only available for mobile customers, so be sure to take advantage of these free downloads today.
Orbitz Customers Are Truly #1
Orbitz takes pride in providing the best customer experience possible, and that effort doesn't end with discount flights to South America or user-friendly mobile apps and web tools. Orbitz Customer Service is always ready to answer questions and help you with booking, planning, or canceling your South America flights. When you need us, we’re here for you!
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.