$128 Cheap flights to South America

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Top places to visit in South America

Cheap flights to South America from $128 One Way, $279 Round Trip

$279 return flights and $128 one-way flights to South America were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
MIABogotáAugust 29 to September 3$426
MIAQuitoAugust 30 to September 1$550
MIABelemAugust 30 to October 7$630
MIABuenos AiresAugust 30 to September 4$673
MIACórdobaAugust 30 to September 20$745
MIASantiagoAugust 29 to September 5$762
MIASão PauloAugust 29 to September 2$780
MIASalvadorAugust 29 to September 5$814
JFKSalvadorAugust 29 to September 6$937
LGWBogotáAugust 30 to September 11$1,204
FCOLimaAugust 29 to September 14$1,297
FCOBuenos AiresAugust 30 to September 7$1,457
LGWSão PauloAugust 29 to September 5$1,684
BKKSão PauloAugust 30 to September 11$1,735
BKKRio de JaneiroAugust 30 to September 14$2,016
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic South America Accommodation Deals

Padama Hotel

Padama Hotel

3.5 out of 5
Av. El Olivar 1238 Callao Lima
Fully refundableReserve now, pay when you stay
$30 nightly
The price is $30 total per night from Sep 26 to Sep 27
$30 total
Sep 26 - Sep 27
Stay at this hotel in Callao. Enjoy free WiFi, private hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Plaza ...
7.4/10 Good! (1,005 reviews)
"Poco amables"

Reviewed on Aug 27, 2026

Opens in a new windowPadama Hotel
Hotel Dorado Plaza Centro Histórico

Hotel Dorado Plaza Centro Histórico

3 out of 5
Carrera 9 31-72 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $65 total per night from Aug 28 to Aug 29
$65 total
Aug 28 - Aug 29
Stay at this hotel in Cartagena. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (535 reviews)
"There is hot water in the shower and the place"

Reviewed on Aug 22, 2026

Opens in a new windowHotel Dorado Plaza Centro Histórico
Quito Airport Suites

Quito Airport Suites

2.5 out of 5
Conector Alpachaca N8-233 Tababela
$60 nightly
The price is $65 total per night from Aug 30 to Aug 31
$65 total
Aug 30 - Aug 31
Book a stay at this family-friendly guesthouse in Tababela. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Opens in a new windowQuito Airport Suites
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Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Plaza de Armas and Costanera Center are located ...
Opens in a new windowAltura Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top South America Apartment Hotels

Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Plaza de Armas and Costanera Center are located ...
Opens in a new windowAltura Suites
Sites Hotel

Sites Hotel

4 out of 5
Carrera 45 No. 5 - 15 Medellín
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $73 total per night from Sep 26 to Sep 27
$73 total
Sep 26 - Sep 27
Book a stay at this business-friendly aparthotel in Medellín. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9.2/10 Wonderful! (1,157 reviews)
"This was my second visit to Sites Hotel. I love the location and staff. The apartment was clean, everything worked well. The offered breakfast was delicious. The building danced during the earthquake...so it is well constructed. There is remodeling going, hopefully it will be finished soon."

Reviewed on Aug 16, 2026

Opens in a new windowSites Hotel
Hotel Du Parc

Hotel Du Parc

4.5 out of 5
Calle 9 Nº 41 - 36 Medellín Antioquia
Fully refundable
$163 nightly
The price is $163 total per night from Sep 1 to Sep 2
$163 total
Sep 1 - Sep 2
Book a stay at this luxury hotel in Medellín. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,008 reviews)
"Exceptional service, amenities, beauty. Without comparison in Poblado."

Reviewed on Aug 25, 2026

Opens in a new windowHotel Du Parc
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Lancaster House

Lancaster House

4 out of 5
Paralela Autonorte No 106B - 28 Bogotá Distrito Capital
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $71 total per night from Aug 28 to Aug 29
$71 total
Aug 28 - Aug 29
Book a stay at this spa hotel in Bogotá. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the overall value in ...
8.6/10 Excellent! (1,000 reviews)
"Nice hotel. Friendly and helpful staff. Pretty good breakfast. Comfortable. The only problem, and it is a big one, is the wifi. It is too weak to be useful. They gave me a plug in hotspot to use and it didn't solve the problem. I had to work while there and the wifi was insufficient for me to work. ..."

Reviewed on Aug 24, 2026

Opens in a new windowLancaster House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic South America Accommodation Deals

Rochester Classic

Rochester Classic

3.5 out of 5
Esmeralda 542 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $68 total per night from Sep 25 to Sep 26
$68 total
Sep 25 - Sep 26
Book a stay at this business-friendly hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida ...
7.8/10 Good! (424 reviews)
"I didnt like the poor breakfast"

Reviewed on Jul 25, 2026

Opens in a new windowRochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
25 De Mayo, 764 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $113 total per night from Sep 12 to Sep 13
$113 total
Sep 12 - Sep 13
Book a stay at this luxury hotel in Buenos Aires. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,001 reviews)
"diseño de los baños y los muebles muestra algo de antigüedad, aunque se mantiene limpio y funcional."

Reviewed on Aug 19, 2026

Opens in a new windowRegal Pacific Buenos Aires
Concorde Hotel

Concorde Hotel

3 out of 5
25 De Mayo 630 Buenos Aires Capital Federal
Stay at this hotel in Buenos Aires. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Obelisco and Florida Street are located ...
6.6/10 (301 reviews)
Good located and no expensive hotel in Buenos Aire
"Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city."

Reviewed on Mar 6, 2018

Opens in a new windowConcorde Hotel
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Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $80 total per night from Aug 28 to Aug 29
$80 total
Aug 28 - Aug 29
Book a stay at this business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Opens in a new windowAlmacruz Hotel y Centro de Convenciones
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in South America

Hotel Las Americas Torre del Mar
Great for families

Hotel Las Americas Torre del Mar

4.5 out of 5
Anillo Vial, Sector Cielo Mar, Torre 2 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$222 nightly
The price is $222 total per night from Aug 30 to Aug 31
$222 total
Aug 30 - Aug 31
Book a stay at this luxury hotel in Cartagena. Enjoy free WiFi, free parking, and 5 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,001 reviews)

Families like: Outdoor pools, kids club, playground, miniature golf

Travelers say...
"Just dirty. Room smelled like mildew and floor was covered in debris. Air conditioning didn’t work so unable to sleep. The rooftop pool was adults only, which we didn’t know, so we’re disappointed as we travelled with kids. The ONLY good thing was the gym."

Reviewed on Aug 27, 2026

Opens in a new windowHotel Las Americas Torre del Mar
Agora Suites Self-Service Boutique Hotel

Agora Suites Self-Service Boutique Hotel

3 out of 5
Calle 67B No. 60-67 Bogotá Bogota D.C.
$57 nightly
The price is $57 total per night from Aug 29 to Aug 30
$57 total
Aug 29 - Aug 30
Stay at this hotel in Bogotá. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Popular attractions 93 Park and Movistar Arena are located ...
9/10 Wonderful! (193 reviews)
"Great property but be warned, no one after hours is there to greet you. After hours in my case was 7 pm. Though the next day, the maid was gone and no one there by 3 pm. Ideally you have communicated before on WhatsApp and have both the door code and the room code recorded. If not, assuming you have ..."

Reviewed on Oct 29, 2024

Opens in a new windowAgora Suites Self-Service Boutique Hotel
Las Americas Casa de Playa
Great for families

Las Americas Casa de Playa

4 out of 5
Anillo Vial Sector Cielo Mar Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$165 nightly
The price is $165 total per night from Sep 27 to Sep 28
$165 total
Sep 27 - Sep 28
Book a stay at this beach hotel in Cartagena. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
Opens in a new windowLas Americas Casa de Playa
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Hilton Cartagena
Great for families

Hilton Cartagena

4.5 out of 5
Avenida Almirante Brion, El Laguito Cartagena
Fully refundableReserve now, pay when you stay
$214 nightly
The price is $214 total per night from Sep 20 to Sep 21
$214 total
Sep 20 - Sep 21
Book a stay at this luxury resort in Cartagena. Enjoy free parking, 4 outdoor pools, and a full-service spa. Our guests praise the helpful staff and the clean ...
Opens in a new windowHilton Cartagena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

South America

Why search for low cost fares on your flights to South America when Orbitz offers the guaranteed lowest prices on foreign and domestic flights? When you travel with Orbitz you can benefit from:

Bargain Flights to South America

Orbitz offers massive discounts and substantial last-minute savings on your South America flights. Orbitz ensures that you can find, plan and reserve your flights any destination with ease, all while enjoying the guaranteed lowest prices available anywhere.

Cutting-Edge Mobile Tools to Keep You In The Know

Orbitz sends you free alerts and updates on your South America flight wherever you are in the world. Once you have downloaded the free app for your iPhone, Android, or iPad, you can review or alter any travel plans that you have made or even book a future flight for business or pleasure. If you need to reserve a hotel room when booking your flight, you will find exclusive deals on our mobile site.

Frequent Flyer Program Enrolment

Orbitz finds you the lowest fares, but you can still add your miles to your frequent flyer program to earn miles or points on selected flights to South America. When making your booking, reference your frequent flyer number to receive discounts in the future.

Outstanding Customer Service

Orbitz values your business and wants to ensure that all of your flights are as easy as possible to book. If you have booked a flight to South America but need to cancel it, you may be able to do so online. If you have any questions or need help, the dedicated Orbitz customer service team is always standing by.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.