$106 Cheap flights to South America

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Top places to visit in South America

Cheap flights to South America from $106 One Way, $234 Round Trip

$234 return flights and $106 one-way flights to South America were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
MIABogotáFebruary 22 to February 27$333
JFKBogotáFebruary 21 to February 27$344
MIALimaFebruary 20 to March 8$366
MIAQuitoFebruary 22 to February 28$476
MIABuenos AiresFebruary 20 to February 24$701
MIASao PauloFebruary 20 to February 25$831
MIACordobaFebruary 20 to March 7$839
MIARio de JaneiroFebruary 20 to March 20$910
MIABelemFebruary 20 to February 24$939
LHRBogotáFebruary 20 to February 24$1,004
MIASalvadorFebruary 21 to February 28$1,125
LHRLimaFebruary 20 to March 5$1,166
LHRSao PauloFebruary 20 to February 22$1,211
LHRBuenos AiresFebruary 22 to March 1$1,578
LHRRio de JaneiroFebruary 21 to February 28$1,662
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic South America Accommodation Deals

Padama Hotel

Padama Hotel

3.5 out of 5
Av. El Olivar 1238 Callao Lima
Fully refundableReserve now, pay when you stay
Stay at this hotel in Callao. Enjoy free WiFi, private hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Plaza ...
7.2/10 Good! (1,001 reviews)
Room was clean. Staff were helpful. Bed was comfortable.

Reviewed on Dec 2, 2025

Opens in a new windowPadama Hotel
Hotel Dorado Plaza Centro Histórico

Hotel Dorado Plaza Centro Histórico

3 out of 5
Carrera 9 31-72 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
Stay at this hotel in Cartagena. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (510 reviews)
Súper bien ubicado, el staff muy amable, la habitación muy cómoda

Reviewed on Dec 31, 2025

Opens in a new windowHotel Dorado Plaza Centro Histórico
Quito Airport Suites

Quito Airport Suites

2.5 out of 5
E8-233 Conector Alpachaca Tababela Pichincha
$44 nightly
The price is $49 total per night from Mar 5 to Mar 6
$49 total
Mar 5 - Mar 6
Book a stay at this family-friendly guesthouse in Tababela. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (728 reviews)
Room was clean and huge. Staff was warm and considerate

Reviewed on Jan 23, 2026

Opens in a new windowQuito Airport Suites
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Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco Mall are ...
Had everything we need for a good stay in Santiago. Grocery very near as well as metro system, buses also.

Reviewed on Mar 17, 2020

Opens in a new windowAltura Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top South America Apartment Hotels

Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco Mall are ...
Had everything we need for a good stay in Santiago. Grocery very near as well as metro system, buses also.

Reviewed on Mar 17, 2020

Opens in a new windowAltura Suites
Sites Hotel

Sites Hotel

4 out of 5
Carrera 45 No. 5 - 15 Medellín
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $110 total per night from Feb 16 to Feb 17
$110 total
Feb 16 - Feb 17
Book a stay at this business-friendly aparthotel in Medellín. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9.2/10 Wonderful! (1,127 reviews)
Great staff. I also liked the location, there are a few restaurants on the street but it’s still quiet.

Reviewed on Jan 30, 2026

Opens in a new windowSites Hotel
Hotel Du Parc

Hotel Du Parc

4.5 out of 5
Calle 9 Nº 41 - 36 Medellín Antioquia
Fully refundableReserve now, pay when you stay
$184 nightly
The price is $184 total per night from Feb 16 to Feb 17
$184 total
Feb 16 - Feb 17
Book a stay at this luxury hotel in Medellín. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,002 reviews)
The staff was very professional. The room was amazing great biew of the city 10/10

Reviewed on Feb 8, 2026

Opens in a new windowHotel Du Parc
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Lancaster House

Lancaster House

4 out of 5
Paralela Autonorte No 106B - 28 Bogotá Distrito Capital
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Bogotá. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the overall value in ...
8.4/10 Very Good! (1,007 reviews)
Very clean. Very friendly staff who were always ready to assist.

Reviewed on Feb 8, 2026

Opens in a new windowLancaster House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic South America Accommodation Deals

Rochester Classic

Rochester Classic

3.5 out of 5
Esmeralda 542 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $80 total per night from Feb 17 to Feb 18
$80 total
Feb 17 - Feb 18
Book a stay at this business-friendly hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida ...
7.8/10 Good! (410 reviews)
Mis padres estuvieron muy contentos con el servicio del hotel, el personal fue muy amable y colaborativo.

Reviewed on Nov 22, 2025

Opens in a new windowRochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
25 De Mayo, 764 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Buenos Aires. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,003 reviews)
I like the hotel, it's close to Puerto Madero. My only complaint is that there aren't many options for things to do at night.

Reviewed on Feb 11, 2026

Opens in a new windowRegal Pacific Buenos Aires
Concorde Hotel

Concorde Hotel

3 out of 5
25 De Mayo 630 Buenos Aires Capital Federal
Stay at this hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida Street are located ...
Good located and no expensive hotel in Buenos Aire
Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city.

Reviewed on Mar 6, 2018

Opens in a new windowConcorde Hotel
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Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $67 total per night from Feb 20 to Feb 21
$67 total
Feb 20 - Feb 21
Book a stay at this business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (660 reviews)
Good place to stay right downtown. But, like any large city you need to be careful. Lots of shopping and historical sites all within walking distance. Property is a little tired but very clean with super interesting decor. Overall a good spot for a 30 hour layover!

Reviewed on Jan 21, 2026

Opens in a new windowAlmacruz Hotel y Centro de Convenciones
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in South America

Hotel Las Americas Torre del Mar
Great for families

Hotel Las Americas Torre del Mar

4.5 out of 5
Anillo Vial, Sector Cielo Mar, Torre 2 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$221 nightly
The price is $221 total per night from Feb 17 to Feb 18
$221 total
Feb 17 - Feb 18
Book a stay at this luxury hotel in Cartagena. Enjoy free WiFi, free parking, and 5 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,001 reviews)

Families like: Outdoor pools, kids club, playground, miniature golf

Travelers say...
Excelente!!

Reviewed on Feb 12, 2026

Opens in a new windowHotel Las Americas Torre del Mar
Agora Suites Self-Service Boutique Hotel

Agora Suites Self-Service Boutique Hotel

3 out of 5
Calle 67B No. 60-67 Bogotá Bogota D.C.
Stay at this hotel in Bogotá. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Popular attractions Andino Shopping Center and Salitre Plaza ...
Great property but be warned, no one after hours is there to greet you. After hours in my case was 7 pm. Though the next day, the maid was gone and no one there by 3 pm. Ideally you have communicated before on WhatsApp and have both the door code and the room code recorded. If not, assuming you have ...

Reviewed on Oct 29, 2024

Opens in a new windowAgora Suites Self-Service Boutique Hotel
Las Americas Casa de Playa
Great for families

Las Americas Casa de Playa

4 out of 5
Anillo Vial Sector Cielo Mar Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$176 nightly
The price is $176 total per night from Feb 22 to Feb 23
$176 total
Feb 22 - Feb 23
Book a stay at this beach hotel in Cartagena. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,012 reviews)

Families like: Outdoor pools, waterslide, kids club, playground

Travelers say...
Adult only pool

Reviewed on Feb 1, 2026

Opens in a new windowLas Americas Casa de Playa
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Hilton Cartagena
Great for families

Hilton Cartagena

4.5 out of 5
Avenida Almirante Brion, El Laguito Cartagena
Fully refundableReserve now, pay when you stay
$197 nightly
The price is $197 total per night from Mar 4 to Mar 5
$197 total
Mar 4 - Mar 5
Book a stay at this luxury resort in Cartagena. Enjoy free parking, 4 outdoor pools, and a full-service spa. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,355 reviews)

Families like: Outdoor pools, waterslide, playground, close to beach

Travelers say...
Very clean room.

Reviewed on Feb 11, 2026

Opens in a new windowHilton Cartagena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

South America

If you are looking for affordable flights to South America, look no further. Orbitz offers discounted rates to many destinations.

Bargain flights to South America now available

As you review your budget and travel plans, consider the low fares Orbitz offers on South America flights. With Orbitz, booking flights to South America is easy and the lowest prices are guaranteed.

Easy self-help service offered

Orbitz offers cutting edge mobile tools that allow you to review and make bookings from your Android or iPhone mobile device with a simple application. You can easily and conveniently update your information or book your trip using this service. You are also able to obtain information on affordable hotel packages and receive frequent flight updates. You will receive confirmation of bookings or reservations made using the mobile service on the same day of the request. Change details or receive updates on your South America flights by visiting the Orbitz site or mobile application.

Orbitz looks after you

Orbitz ensures that you are kept informed with up-to-date flight information, providing feedback to up to six contact numbers to ensure that everyone receives the feedback. In addition to providing the discounted deals on South America flights, Orbitz is also able to structure a package based on your needs for activities, car hire and accommodations.

Traveler profile updates

After booking your South America flights, you may access your account profile on the Orbitz site and update your frequent flyer or loyalty membership details. This information will remain on the system and will be available for you to access when you make any future bookings with Orbitz.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.