$167 Cheap flights to South America

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Top places to visit in South America

Cheap flights to South America from $167 One Way, $362 Round Trip

$362 return flights and $167 one-way flights to South America were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
MIABogotáMay 30 to June 1$370
MIAQuitoMay 29 to June 11$490
MIALimaMay 31 to June 6$528
MIABuenos AiresMay 31 to June 3$702
MIASão PauloMay 29 to June 19$727
MIASantiagoMay 29 to June 3$765
MIACórdobaMay 29 to June 12$856
LHRSão PauloMay 29 to June 6$1,087
LHRLimaMay 30 to June 19$1,091
LHRRio de JaneiroMay 29 to June 21$1,095
LGWBogotáMay 31 to June 16$1,178
LHRSantiagoMay 31 to June 7$1,237
LHRQuitoMay 29 to June 14$1,535
SINSantiagoMay 31 to June 16$1,797
SINLimaMay 29 to June 13$3,448
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic South America Accommodation Deals

Padama Hotel

Padama Hotel

3.5 out of 5
Av. El Olivar 1238 Callao Lima
Fully refundableReserve now, pay when you stay
$25 nightly
The price is $25 total per night from May 24 to May 25
$25 total
May 24 - May 25
Stay at this hotel in Callao. Enjoy free WiFi, private hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Plaza ...
7.4/10 Good! (1,000 reviews)
"Il y avait un maudit coq sur le toit de l'édifice juste de l'autre côté de ma fenêtre alors vous devinez la suite Grande chambre et propre"

Reviewed on May 17, 2026

Opens in a new windowPadama Hotel
Hotel Dorado Plaza Centro Histórico

Hotel Dorado Plaza Centro Histórico

3 out of 5
Carrera 9 31-72 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $55 total per night from May 24 to May 25
$55 total
May 24 - May 25
Stay at this hotel in Cartagena. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (519 reviews)
"Good location if you want some budget option"

Reviewed on May 18, 2026

Opens in a new windowHotel Dorado Plaza Centro Histórico
Quito Airport Suites

Quito Airport Suites

2.5 out of 5
E8-233 Conector Alpachaca Tababela Pichincha
$44 nightly
The price is $49 total per night from May 26 to May 27
$49 total
May 26 - May 27
Book a stay at this family-friendly guesthouse in Tababela. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (741 reviews)
"Great service and the staff very nice and friendly"

Reviewed on May 12, 2026

Opens in a new windowQuito Airport Suites
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Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Julio Martinez Pradanos ...
Opens in a new windowAltura Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top South America Apartment Hotels

Altura Suites

Altura Suites

4 out of 5
Merced 562, departamento 1006A Santiago Region Metropolitana
Stay at this aparthotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Julio Martinez Pradanos ...
Opens in a new windowAltura Suites
Sites Hotel

Sites Hotel

4 out of 5
Carrera 45 No. 5 - 15 Medellín
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $90 total per night from May 24 to May 25
$90 total
May 24 - May 25
Book a stay at this business-friendly aparthotel in Medellín. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9.2/10 Wonderful! (1,147 reviews)
"Hotel was great would recommend to anyone.Minutes from all spots and very safe"

Reviewed on May 7, 2026

Opens in a new windowSites Hotel
Hotel Du Parc

Hotel Du Parc

4.5 out of 5
Calle 9 Nº 41 - 36 Medellín Antioquia
Fully refundable
$154 nightly
The price is $154 total per night from Jun 6 to Jun 7
$154 total
Jun 6 - Jun 7
Book a stay at this luxury hotel in Medellín. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,003 reviews)
"I love the location and charm of the hotel. The staff was excellent, friendly helpful and efficient. The room was large and comfortable with a wonderful roomy shower. Their inclusive breakfast was also quite good. The only issues are that immediately surrounding the property, there was significant ..."

Reviewed on May 22, 2026

Opens in a new windowHotel Du Parc
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Lancaster House

Lancaster House

4 out of 5
Paralela Autonorte No 106B - 28 Bogotá Distrito Capital
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $59 total per night from May 24 to May 25
$59 total
May 24 - May 25
Book a stay at this spa hotel in Bogotá. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the overall value in ...
8.6/10 Excellent! (1,000 reviews)
"Staff should improve service at the restaurant. Breakfast ok."

Reviewed on May 20, 2026

Opens in a new windowLancaster House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic South America Accommodation Deals

Rochester Classic

Rochester Classic

3.5 out of 5
Esmeralda 542 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $72 total per night from May 25 to May 26
$72 total
May 25 - May 26
Book a stay at this business-friendly hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida ...
7.8/10 Good! (418 reviews)
"Everything was good, I booked a room for my parents they love it, staff was so nice and kind, room was clean. Thank you!"

Reviewed on Apr 3, 2026

Opens in a new windowRochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
25 De Mayo, 764 Buenos Aires Capital Federal
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $109 total per night from May 30 to May 31
$109 total
May 30 - May 31
Book a stay at this luxury hotel in Buenos Aires. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,002 reviews)
"clean room, nice stadff, good breakfast"

Reviewed on May 22, 2026

Opens in a new windowRegal Pacific Buenos Aires
Concorde Hotel

Concorde Hotel

3 out of 5
25 De Mayo 630 Buenos Aires Capital Federal
Stay at this hotel in Buenos Aires. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Obelisco and Florida Street are located ...
6.6/10 (301 reviews)
Good located and no expensive hotel in Buenos Aire
"Is an hotel located in micro center of Buenos Aires, near turístic atractives such us Casa Rosada and Puerto Madero, and near a subway station that permits get connected with all the city."

Reviewed on Mar 6, 2018

Opens in a new windowConcorde Hotel
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Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $59 total per night from May 31 to Jun 1
$59 total
May 31 - Jun 1
Book a stay at this business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (692 reviews)
"Todo bien con el hotel y la habitación, excepto que no aparece en la descripción que el estacionamiento está a 3 cuadras del hotel !!! Es algo que deberían transparentar..."

Reviewed on May 12, 2026

Opens in a new windowAlmacruz Hotel y Centro de Convenciones
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in South America

Hotel Las Americas Torre del Mar
Great for families

Hotel Las Americas Torre del Mar

4.5 out of 5
Anillo Vial, Sector Cielo Mar, Torre 2 Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $179 total per night from May 24 to May 25
$179 total
May 24 - May 25
Book a stay at this luxury hotel in Cartagena. Enjoy free WiFi, free parking, and 5 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,003 reviews)

Families like: Outdoor pools, kids club, playground, miniature golf

Travelers say...
"Changed room 3 times. No hot water. Other room water raining from our cieling. They charge for a pod of coffee in your room. The prices are miami beach prices."

Reviewed on May 21, 2026

Opens in a new windowHotel Las Americas Torre del Mar
Agora Suites Self-Service Boutique Hotel

Agora Suites Self-Service Boutique Hotel

3 out of 5
Calle 67B No. 60-67 Bogotá Bogota D.C.
Stay at this hotel in Bogotá. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Popular attractions Movistar Arena and Estadio Nemesio Camacho ...
9/10 Wonderful! (193 reviews)
"Great property but be warned, no one after hours is there to greet you. After hours in my case was 7 pm. Though the next day, the maid was gone and no one there by 3 pm. Ideally you have communicated before on WhatsApp and have both the door code and the room code recorded. If not, assuming you have ..."

Reviewed on Oct 29, 2024

Opens in a new windowAgora Suites Self-Service Boutique Hotel
Las Americas Casa de Playa
Great for families

Las Americas Casa de Playa

4 out of 5
Anillo Vial Sector Cielo Mar Cartagena Bolivar
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $159 total per night from Jun 20 to Jun 21
$159 total
Jun 20 - Jun 21
Book a stay at this beach hotel in Cartagena. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,000 reviews)

Families like: Outdoor pools, waterslide, kids club, playground

Travelers say...
"Todo perfecto"

Reviewed on May 11, 2026

Opens in a new windowLas Americas Casa de Playa
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Hilton Cartagena
Great for families

Hilton Cartagena

4.5 out of 5
Avenida Almirante Brion, El Laguito Cartagena
Fully refundableReserve now, pay when you stay
$188 nightly
The price is $188 total per night from Jun 2 to Jun 3
$188 total
Jun 2 - Jun 3
Book a stay at this luxury resort in Cartagena. Enjoy free parking, 4 outdoor pools, and a full-service spa. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,428 reviews)

Families like: Outdoor pools, waterslide, playground, close to beach

Travelers say...
"It was great!"

Reviewed on May 22, 2026

Opens in a new windowHilton Cartagena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

South America

Orbitz uses cutting edge mobile technology to help get you the best deals on South America flights. We offer guaranteed low prices on air tickets that can be combined with hotels and car rentals to save you even more money.

Find Cheap South America Flights And Hotel Rooms Using Our Mobile App

Orbitz not only guarantees low prices for flights to South America, we also offer Mobile Steals on our Orbitz on the Go mobile app where you can find great mobile-only deals on hotel rooms in the area.

Use the Orbitz Flight Matrix To Save Big On Car Rental

Discount flights to South America can be combined with car rental to get you additional savings. Just use our Flight Matrix to see how your budget air ticket can be combined with a car rental to make your trip not only inexpensive but also more convenient.

Use Multiple Airlines To Ensure You Get The Best Deal

Orbitz allows you to use multiple airlines for flights to South America. By using a combination of airlines for discount flights you are guaranteed to get the lowest fares each way and get the schedule that is most convenient for you.

Store Your Frequent Flyer Information on Orbitz For Easy Access

Booking with Orbitz will still allow you to apply miles for flights to South America to your frequent flyer program. Not only that, but your frequent flyer information will be safely stored on our website, so it will be easy to access the next time you book a discount air ticket with Orbitz.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.