Hotels in Serra Mesa
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Featured Hotels in Serra Mesa

Best Western Seven Seas
411 Hotel Circle South San Diego CA
Free Cancellation
Reserve now, pay when you stay
3.31 mi from Serra Mesa
$82 nightly
The price is $94 total per night
$94 total
Jun 2 - Jun 3
Total with taxes and fees
Guests of Best Western Seven Seas have access to an outdoor pool, a gym, and 2 hot tubs. Free parking is included with your stay. The front desk has multilingual staff on hand 24/7 to help with luggage storage, securing valuables, and concierge services. Additional amenities include free WiFi in public areas, conference space, and a business center.
Pool
Hot Tub

Handlery Hotel
950 Hotel Cir N San Diego CA
3.52 mi from Serra Mesa
$122 nightly
The price is $140 total per night
$140 total
Jun 16 - Jun 17
Total with taxes and fees
At Handlery Hotel, guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. Self parking is available for USD 24 per night. The 24-hour front desk has multilingual staff ready to assist with luggage storage, dry cleaning/laundry, and concierge services. Additional amenities include a hot tub, meeting rooms, and conference space.
Pool
Hot Tub

California Suites Hotel
5415 Clairemont Mesa Blvd San Diego CA
Free Cancellation
Reserve now, pay when you stay
2.98 mi from Serra Mesa
$86 nightly
The price is $99 total per night
$99 total
May 20 - May 21
Total with taxes and fees
California Suites Hotel offers an outdoor pool, free WiFi in public areas, and a hot tub. Free parking is included with your stay. The 24-hour front desk has multilingual staff ready to help with luggage storage, and answer any questions about the area. Additional amenities include conference space, a microwave in a common area, and express check-out.
Pool
Hot Tub

The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue San Diego CA
Free Cancellation
Reserve now, pay when you stay
5.74 mi from Serra Mesa
$119 nightly
The price is $138 total per night
$138 total
May 26 - May 27
Total with taxes and fees
Guests of The DEXTRO Little Italy, BW Premier Collection have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 35.00 per day. The front desk has multilingual staff standing by 24 hours a day to assist with concierge services and luggage storage. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Free WiFi

Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
Free Cancellation
Reserve now, pay when you stay
6.12 mi from Serra Mesa
$174 nightly
The price is $201 total per night
$201 total
May 25 - May 26
Total with taxes and fees
Guests of Wyndham San Diego Bayside have access to an outdoor pool, a gym, and free WiFi in public areas. Self parking is offered for USD 50.00 per night. Multilingual staff at the 24-hour front desk can assist with luggage storage, concierge services, and dry cleaning/laundry. Additional amenities include meeting rooms, a conference center, and a business center.
Pool
Pet friendly

The Sofia Hotel
150 W Broadway San Diego CA
Free Cancellation
Reserve now, pay when you stay
6.2 mi from Serra Mesa
$168 nightly
The price is $194 total per night
$194 total
May 27 - May 28
Total with taxes and fees
At The Sofia Hotel, guests have access to a 24-hour gym, free WiFi in public areas, and a business center. Valet parking is offered for USD 50 per night. The 24-hour front desk has multilingual staff ready to assist with dry cleaning/laundry, concierge services, and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this historic hotel include free use of bicycles, express check-out, and free newspapers.
Pet friendly
Free WiFi

Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
Free Cancellation
Reserve now, pay when you stay
6.63 mi from Serra Mesa
$263 nightly
The price is $305 total per night
$305 total
May 25 - May 26
Total with taxes and fees
Guests staying at Manchester Grand Hyatt San Diego enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is offered for USD 65 per night. Multilingual staff at the 24-hour front desk can assist with tours or tickets, securing valuables, and luggage storage. Additional amenities include a hot tub, meeting rooms, and conference space.
Pool
Hot Tub

Hard Rock Hotel San Diego
207 5th Ave San Diego CA
Free Cancellation
Reserve now, pay when you stay
6.68 mi from Serra Mesa
$203 nightly
The price is $235 total per night
$235 total
May 25 - May 26
Total with taxes and fees
Hard Rock Hotel San Diego features a nightclub, an outdoor pool, and a 24-hour gym. Valet parking is offered for USD 70 per night. Multilingual staff at the 24-hour front desk can assist with luggage storage, tours or tickets, and dry cleaning/laundry. Additional amenities include free WiFi in public areas, meeting rooms, and conference space.
Pool
Free WiFi

Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
Free Cancellation
Reserve now, pay when you stay
6.15 mi from Serra Mesa
$264 nightly
The price is $303 total per night
$303 total
May 21 - May 22
Total with taxes and fees
Paradise Point Resort & Spa features a marina, a full-service spa, and 5 outdoor pools. Self parking is available for USD 49 per night. The front desk has multilingual staff on hand 24/7 to help with luggage storage, tours or tickets, and dry cleaning/laundry. Other amenities at this beach resort include a gym, 5 hot tubs, and a sauna.
Pool
Hot Tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Serra Mesa hotels essential information
Accommodation | 9,147 hotels |
|---|---|
Lowest Price | $94 |
Highest Price | $305 |
Popular hotels | The Sofia Hotel, Paradise Point Resort & Spa, Manchester Grand Hyatt San Diego, Hard Rock Hotel San Diego, The DEXTRO Little Italy, BW Premier Collection, Wyndham San Diego Bayside, Best Western Seven Seas, Handlery Hotel, California Suites Hotel |
Popular places to visit
Stadium Golf Center & Batting Cages
Enjoy a round of golf in San Diego at Stadium Golf Center & Batting Cages. Attend a sporting event or discover the beautiful sunsets in this walkable area.
Recent Reviews

The Sofia Hotel
5/5 Excellent
"The Sophia was an awesome quaint hotel. It had all the amenities. Our room had a street view and in the distance you could see the beach. I wish we would’ve stayed more than one night. Definitely looking forward to staying here again. !"
A verified traveler stayed at The Sofia Hotel
Posted 5 hours ago
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