Hotels in Otay Mesa

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Featured Hotels in Otay Mesa

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Otay Mesa Long Term & Extended Stay Hotels

    Holiday Inn Express San Diego Airport - Old Town, an IHG Hotel

    Holiday Inn Express San Diego Airport - Old Town, an IHG Hotel

    1955 San Diego Ave, San Diego, CA, 92110
    The price is $135 per night from Dec 13 to Dec 14
    $135
    per night
    Dec 13 - Dec 14
    4.3/5 Excellent! (1,142 reviews)
    Hampton Inn San Diego Downtown

    Hampton Inn San Diego Downtown

    1531 Pacific Hwy, San Diego, CA, 92101
    The price is $117 per night from Dec 23 to Dec 24
    $117
    per night
    Dec 23 - Dec 24
    4/5 Very Good! (1,004 reviews)
    Howard Johnson by Wyndham San Diego Sea World

    Howard Johnson by Wyndham San Diego Sea World

    3330 Rosecrans Street, San Diego, CA, 92110
    The price is $110 per night from Dec 11 to Dec 12
    $110
    per night
    Dec 11 - Dec 12
    3.4/5 Good! (998 reviews)

Luxury Hotels in Otay Mesa

    Embassy Suites by Hilton San Diego Bay Downtown

    Embassy Suites by Hilton San Diego Bay Downtown

    601 Pacific Hwy, San Diego, CA, 92101
    The price is $198 per night from Dec 18 to Dec 19
    $198
    per night
    Dec 18 - Dec 19
    4.2/5 Excellent! (1,722 reviews)
    Country Inn & Suites by Radisson, San Diego North, CA

    Country Inn & Suites by Radisson, San Diego North, CA

    5975 Lusk Blvd, San Diego, CA, 92121
    The price is $156 per night from Dec 18 to Dec 19
    $156
    per night
    Dec 18 - Dec 19
    4.3/5 Excellent! (1,242 reviews)
    Best Western Yacht Harbor Hotel

    Best Western Yacht Harbor Hotel

    5005 N Harbor Dr, San Diego, CA, 92106
    The price is $116 per night from Dec 11 to Dec 12
    $116
    per night
    Dec 11 - Dec 12
    4.1/5 Very Good! (1,395 reviews)

Pet Friendly Otay Mesa Hotels

    The Sofia Hotel

    The Sofia Hotel

    150 W Broadway, San Diego, CA, 92101
    The price is $230 per night from Jan 2 to Jan 3
    $230
    per night
    Jan 2 - Jan 3
    4/5 Very Good! (1,751 reviews)
    Country Inn & Suites by Radisson, San Diego North, CA

    Country Inn & Suites by Radisson, San Diego North, CA

    5975 Lusk Blvd, San Diego, CA, 92121
    The price is $156 per night from Dec 18 to Dec 19
    $156
    per night
    Dec 18 - Dec 19
    4.3/5 Excellent! (1,242 reviews)
    Wyndham San Diego Bayside

    Wyndham San Diego Bayside

    1355 N Harbor Drive, San Diego, CA, 92101
    The price is $152 per night from Dec 18 to Dec 19
    $152
    per night
    Dec 18 - Dec 19
    4/5 Very Good! (5,721 reviews)
Otay Mesa Hotels

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Great selection of hotels in Otay Mesa

Whether you're searching for hotels in Otay Mesa on business, or hunting for a family getaway, Otay Mesa hotel options are only a click away. Find hotels in Otay Mesa with the location, star-rating and facilities you need. Narrow your search results even further by star rating, hotel chain and amenities, such as free parking, babysitting services, or fitness centers. And with area maps, you can view Otay Mesa hotels close you are to the airport and nearby attractions.

Otay Mesa hotel reviews, photos and virtual tours

Thanks to photos and virtual tours, you can look before you book your Otay Mesa hotel reservation. Check out Otay Mesa hotel properties using interactive tools which allow you view hotel rooms, common areas and key features. On Orbitz, you can also learn more about hotels in Otay Mesa with unbiased reviews from verified Otay Mesa hotel guests. We ask guests to offer candid feedback on services, comfort, location, value and amenities.

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On Orbitz, Otay Mesa hotel deals mean flexibility. If you need to change your Otay Mesa hotel reservations, or cancel your stay, Orbitz doesn't charge cancel or change fees. Orbitz also offers great selection on airline tickets, vacation packages, and car rental deals to so you can plan your trip to Otay Mesa all in one place.

 

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