Book 5 Star Hotels in Kearny Mesa
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Featured Kearny Mesa 5 Stars Hotels
Four Points by Sheraton San Diego
8110 Aero Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
1.38 mi from Kearny Mesa
$116 nightly
The price is $133 total per night
$133 total
Jan 10 - Jan 11, 2026
Total with taxes and fees
Guests of Four Points by Sheraton San Diego have access to an outdoor pool, a gym, and free WiFi in public areas. Self parking is available for USD 16 per night. Multilingual staff at the 24-hour front desk can assist with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include a hot tub, meeting rooms, and a conference center.
Pool
Hot Tub
Hilton Garden Inn San Diego Mission Valley Stadium
3805 Murphy Canyon Rd San Diego CA
Free Cancellation
Reserve now, pay when you stay
1.9 mi from Kearny Mesa
$105 nightly
The price is $120 total per night
$120 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Guests of Hilton Garden Inn San Diego Mission Valley Stadium have access to an outdoor pool, a gym, and free WiFi in public areas. Self parking is available for USD 16 per day. The front desk is staffed 24/7 to help with luggage storage, dry cleaning/laundry, and tours or tickets. Additional amenities include conference space, a business center, and a computer station.
Pool
Pet friendly
DoubleTree by Hilton Hotel San Diego - Mission Valley
7450 Hazard Center Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
4.2 mi from Kearny Mesa
$112 nightly
The price is $129 total per night
$129 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
DoubleTree by Hilton Hotel San Diego - Mission Valley features an indoor pool, an outdoor pool, and a 24-hour gym. Self parking is available for USD 40 per day. The front desk has multilingual staff on hand 24/7 to help with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include free WiFi in public areas, a hot tub, and express check-out.
Pool
Hot Tub
San Diego Marriott La Jolla
4240 La Jolla Village Dr La Jolla CA
Free Cancellation
Reserve now, pay when you stay
5.26 mi from Kearny Mesa
$155 nightly
The price is $178 total per night
$178 total
Jan 9 - Jan 10, 2026
Total with taxes and fees
Guests of San Diego Marriott La Jolla have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. Parking is available for USD 39 per night (USD 49 per night for valet parking), and there's also limo/town car service. Multilingual staff at the 24-hour front desk can assist with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include meeting rooms, conference space, and a business center.
Pool
Pet friendly
Legacy Resort Hotel & Spa
875 Hotel Circle South San Diego CA
Free Cancellation
Reserve now, pay when you stay
5.08 mi from Kearny Mesa
$152 nightly
The price is $175 total per night
$175 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of Legacy Resort Hotel & Spa enjoy a full-service spa, an outdoor pool, and a gym. Self parking is offered for USD 38 per night. Front-desk staff can answer questions 24/7, and assist with securing valuables, concierge services, and luggage storage. Other amenities at this spa hotel include a sauna, free WiFi in public areas, and a hot tub.
Pool
Hot Tub
The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue San Diego CA
Free Cancellation
Reserve now, pay when you stay
7.46 mi from Kearny Mesa
$104 nightly
The price is $121 total per night
$121 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of The DEXTRO Little Italy, BW Premier Collection have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 35.00 per day. The front desk has multilingual staff standing by 24 hours a day to assist with concierge services and luggage storage. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Free WiFi
Courtyard by Marriott San Diego Downtown Little Italy
1646 Front St San Diego CA
Free Cancellation
7.47 mi from Kearny Mesa
$122 nightly
The price is $141 total per night
$141 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of Courtyard by Marriott San Diego Downtown Little Italy have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is offered for USD 40 per day. The front desk has multilingual staff on hand 24/7 to help with luggage storage, securing valuables, and concierge services. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include a living plant wall, a gift shop, and a porter/bellhop.
Pool
Pet friendly
Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
7.72 mi from Kearny Mesa
$156 nightly
The price is $180 total per night
$180 total
Dec 30 - Dec 31
Total with taxes and fees
Guests of Sheraton San Diego Resort have access to a marina, 3 outdoor pools, and a 24-hour gym. Parking is USD 55 per night (USD 67 per night for valet parking)—but if you prefer not to drive, catch a ride in the free airport shuttle during limited hours. Multilingual staff at the 24-hour front desk can assist with luggage storage, concierge services, and access to locker space. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include 2 hot tubs, free WiFi in public areas, and a conference center.
Pool
Hot Tub
Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
9.16 mi from Kearny Mesa
$119 nightly
The price is $137 total per night
$137 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
At Bay Club Hotel & Marina, guests enjoy a marina, an outdoor pool, and a gym. Self parking is available for USD 22 per night. Multilingual staff at the front desk are standing by 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include free WiFi in public areas, a hot tub, and meeting rooms.
Pool
Hot Tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best 5 star hotels in Kearny Mesa
Guarantee yourself a relaxing time when you book the best of the best: 5 star hotels in Kearny Mesa. After all, treating yourself to the finer things is what vacations are about.
What are the criteria for a 5 star hotel?
5 star hotel requirements include distinctive services and amenities that surpass all others. These Kearny Mesa hotels bring an incomparable degree of quality and attention to detail, with guest satisfaction being top priority. Your 5 star hotel should be dressed to impress, with design details like marble surfaces and hi-tech fixtures.
What amenities can I expect at a 5 star hotel?
Kearny Mesa 5 star hotels and resorts typically offer luxury amenities such as:
- Gourmet restaurant
- Full-service fitness center with pool
- Luxury spa
- Welcome gifts upon arrival
- Top-of-the-line beds and linens
- Designer personal care products
- Premium cable, free Wi-Fi and device docking stations
How do I find an amazing 5 star hotel?
Finding 5 star hotel deals in Kearny Mesa with Orbitz is as easy as your stay will be. For the top-shelf vacation you deserve, we’ll help you choose the right hotel in the right place:
- Search hotels by price, ranging from $120 to $180
- Find the best-loved hotels through word-of-mouth advice when you check out over reviews by Orbitz travelers
- Choose from 9,504 5 star hotels in Kearny Mesa!
Kearny Mesa hotels essential information
Accommodation | 9,504 hotels |
|---|---|
Lowest Price | $120 |
Highest Price | $180 |
Popular hotels | Four Points by Sheraton San Diego, Hilton Garden Inn San Diego Mission Valley Stadium, Sheraton San Diego Resort, Bay Club Hotel & Marina, The DEXTRO Little Italy, BW Premier Collection, Courtyard by Marriott San Diego Downtown Little Italy, Legacy Resort Hotel & Spa, San Diego Marriott La Jolla, DoubleTree by Hilton Hotel San Diego - Mission Valley |
Recent Reviews
Four Points by Sheraton San Diego
5/5 Excellent
"Nice"
A verified traveler stayed at Four Points by Sheraton San Diego
Posted 15 hours ago
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