Book 2 Star Hotels in South San Diego
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Featured South San Diego 2 Stars Hotels

The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue San Diego CA
Free Cancellation
Reserve now, pay when you stay
12.19 mi from city center
$104 nightly
The price is $121 total per night
$121 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of The DEXTRO Little Italy, BW Premier Collection have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 35.00 per day. The front desk has multilingual staff standing by 24 hours a day to assist with concierge services and luggage storage. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Free WiFi

Courtyard by Marriott San Diego Downtown Little Italy
1646 Front St San Diego CA
Free Cancellation
12.27 mi from city center
$122 nightly
The price is $141 total per night
$141 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of Courtyard by Marriott San Diego Downtown Little Italy have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is offered for USD 40 per day. The front desk has multilingual staff on hand 24/7 to help with luggage storage, securing valuables, and concierge services. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include a living plant wall, a gift shop, and a porter/bellhop.
Pool
Pet friendly

Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
13.87 mi from city center
$156 nightly
The price is $180 total per night
$180 total
Dec 29 - Dec 30
Total with taxes and fees
Guests of Sheraton San Diego Resort have access to a marina, 3 outdoor pools, and a 24-hour gym. Parking is USD 55 per night (USD 67 per night for valet parking)—but if you prefer not to drive, catch a ride in the free airport shuttle during limited hours. Multilingual staff at the 24-hour front desk can assist with luggage storage, concierge services, and access to locker space. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include 2 hot tubs, free WiFi in public areas, and a conference center.
Pool
Hot Tub

Lafayette Hotel & Club
2223 El Cajon Blvd San Diego CA
Free Cancellation
Reserve now, pay when you stay
13.14 mi from city center
$229 nightly
The price is $263 total per night
$263 total
Dec 29 - Dec 30
Total with taxes and fees
At Lafayette Hotel & Club, guests have access to an outdoor pool, free WiFi in public areas, and meeting rooms. Valet parking is offered for USD 38 per night. The front desk has multilingual staff on hand 24/7 to help with concierge services, dry cleaning/laundry, and luggage storage. Additional amenities include conference space, a gift shop, and a porter/bellhop.
Pool
Pet friendly

Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
14.61 mi from city center
$129 nightly
The price is $148 total per night
$148 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
At Bay Club Hotel & Marina, guests enjoy a marina, an outdoor pool, and a gym. Self parking is available for USD 22 per night. Multilingual staff at the front desk are standing by 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include free WiFi in public areas, a hot tub, and meeting rooms.
Pool
Hot Tub

Hilton San Diego Mission Valley
901 Camino Del Rio S San Diego CA
Free Cancellation
Reserve now, pay when you stay
14.15 mi from city center
$122 nightly
The price is $141 total per night
$141 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
At Hilton San Diego Mission Valley, guests enjoy features like an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is offered for USD 37 per day. The 24-hour front desk has staff standing by to help with securing valuables, concierge services, and dry cleaning/laundry. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Legacy Resort Hotel & Spa
875 Hotel Circle South San Diego CA
Free Cancellation
Reserve now, pay when you stay
14.39 mi from city center
$152 nightly
The price is $175 total per night
$175 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of Legacy Resort Hotel & Spa enjoy a full-service spa, an outdoor pool, and a gym. Self parking is offered for USD 38 per night. Front-desk staff can answer questions 24/7, and assist with securing valuables, concierge services, and luggage storage. Other amenities at this spa hotel include a sauna, free WiFi in public areas, and a hot tub.
Pool
Hot Tub

DoubleTree by Hilton Hotel San Diego - Mission Valley
7450 Hazard Center Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
14.6 mi from city center
$112 nightly
The price is $129 total per night
$129 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
DoubleTree by Hilton Hotel San Diego - Mission Valley features an indoor pool, an outdoor pool, and a 24-hour gym. Self parking is available for USD 40 per day. The front desk has multilingual staff on hand 24/7 to help with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include free WiFi in public areas, a hot tub, and express check-out.
Pool
Hot Tub

The Dana on Mission Bay
1710 W Mission Bay Dr San Diego CA
Free Cancellation
Reserve now, pay when you stay
17.38 mi from city center
$156 nightly
The price is $180 total per night
$180 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of The Dana on Mission Bay have access to a marina, 2 outdoor pools, and a gym. Self parking is available for USD 35 per night. The front desk has multilingual staff standing by 24 hours a day to assist with dry cleaning/laundry and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include 2 hot tubs, a conference center, and a business center.
Pool
Hot Tub
Don't see what you're looking for?
See all available properties in South San Diego
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South San Diego hotels essential information
Accommodation | 7,805 hotels |
|---|---|
Lowest Price | $121 |
Highest Price | $263 |
Popular hotels | Bay Club Hotel & Marina, Sheraton San Diego Resort, The DEXTRO Little Italy, BW Premier Collection, Legacy Resort Hotel & Spa, Courtyard by Marriott San Diego Downtown Little Italy, Hilton San Diego Mission Valley, The Dana on Mission Bay, Lafayette Hotel & Club, DoubleTree by Hilton Hotel San Diego - Mission Valley |
Recent Reviews

Bay Club Hotel & Marina
5/5 Excellent
"Good room, hotel staff, amenities."
A verified traveler stayed at Bay Club Hotel & Marina
Posted 3 days ago
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