Cheap flights from TYS to BUF (McGhee Tyson to Buffalo Niagara Intl.)

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Cheap Flights from TYS to BUF starting at $80 One Way, $143 Round Trip

Prices starting at $143 for return flights and $80 for one-way flights to Buffalo Niagara Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, May 30 - Sat, Jun 1
TYS
Knoxville
BUF
Buffalo
$143 Roundtrip, found 2 hours ago
$143
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Thu, May 30 from Knoxville to Buffalo, returning Sat, Jun 1, priced at $143 found 2 hours ago
Thu, May 30 - Thu, Jun 6
TYS
Knoxville
BUF
Buffalo
$160 Roundtrip, found 4 hours ago
$160
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Thu, May 30 from Knoxville to Buffalo, returning Thu, Jun 6, priced at $160 found 4 hours ago
Sun, May 19 - Wed, May 22
TYS
Knoxville
BUF
Buffalo
$164 Roundtrip, found 5 days ago
$164
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Sun, May 19 from Knoxville to Buffalo, returning Wed, May 22, priced at $164 found 5 days ago
Sun, May 19 - Wed, May 29
TYS
Knoxville
BUF
Buffalo
$168 Roundtrip, found 5 days ago
$168
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Sun, May 19 from Knoxville to Buffalo, returning Wed, May 29, priced at $168 found 5 days ago
Fri, May 24 - Wed, May 29
TYS
Knoxville
BUF
Buffalo
$184 Roundtrip, found 1 day ago
$184
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, May 24 from Knoxville to Buffalo, returning Wed, May 29, priced at $184 found 1 day ago

Hotel Ideas near Buffalo Niagara Intl.

Airport Hotels near Buffalo Niagara Intl.

Buffalo Airport Hotel
Buffalo Airport Hotel
3 out of 5
4600 Genesee St, Buffalo, NY
The price is $104 per night from May 12 to May 13
$104
per night
May 12 - May 13
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the bar ...
8/10 Very Good! (1,972 reviews)
"I have an affinity for this hotel, i have watched the owners turn it into a decent place from being a dump, it could not be more convienent to the airport, and the staff is great"

Reviewed on May 7, 2024

Buffalo Airport Hotel
Comfort Inn & Suites Buffalo Airport
Comfort Inn & Suites Buffalo Airport
3 out of 5
4345 Genesee St, Buffalo, NY
The price is $110 per night from May 28 to May 29
$110
per night
May 28 - May 29
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (439 reviews)
"Best near airport with shuttle options"

Reviewed on May 10, 2024

Comfort Inn & Suites Buffalo Airport
Hilton Garden Inn Buffalo Airport
Hilton Garden Inn Buffalo Airport
3 out of 5
4201 Genesee St, Buffalo, NY
The price is $152 per night from May 26 to May 27
$152
per night
May 26 - May 27
Stay at this 3-star business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,001 reviews)
"Wings were great!"

Reviewed on Apr 27, 2024

Hilton Garden Inn Buffalo Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Buffalo

M Hotel Buffalo
M Hotel Buffalo
3.5 out of 5
2040 Walden Ave, Buffalo, NY
The price is $91 per night from May 12 to May 13
$91
per night
May 12 - May 13
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in ...
6.8/10 (659 reviews)
"Is excellent choice"

Reviewed on May 7, 2024

M Hotel Buffalo
Comfort Inn & Suites Buffalo Airport
Comfort Inn & Suites Buffalo Airport
3 out of 5
4345 Genesee St, Buffalo, NY
The price is $110 per night from May 28 to May 29
$110
per night
May 28 - May 29
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (439 reviews)
"Best near airport with shuttle options"

Reviewed on May 10, 2024

Comfort Inn & Suites Buffalo Airport
Hampton Inn Buffalo - Amherst, NY
Hampton Inn Buffalo - Amherst, NY
2.5 out of 5
1601 Amherst Manor Drive, Buffalo, NY
The price is $118 per night from May 27 to May 28
$118
per night
May 27 - May 28
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,292 reviews)
"had awesome breakfast and the room is very clean. recommended!"

Reviewed on May 9, 2024

Hampton Inn Buffalo - Amherst, NY
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Buffalo Hotels With Airport Transportation

Sleep Inn & Suites Buffalo Airport
Sleep Inn & Suites Buffalo Airport
2.5 out of 5
100 Holtz Dr, Buffalo, NY
The price is $98 per night from May 13 to May 14
$98
per night
May 13 - May 14
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,108 reviews)
"Great location for early airport travel"

Reviewed on May 6, 2024

Sleep Inn & Suites Buffalo Airport
Comfort Inn & Suites Buffalo Airport
Comfort Inn & Suites Buffalo Airport
3 out of 5
4345 Genesee St, Buffalo, NY
The price is $110 per night from May 28 to May 29
$110
per night
May 28 - May 29
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (439 reviews)
"Best near airport with shuttle options"

Reviewed on May 10, 2024

Comfort Inn & Suites Buffalo Airport
Curtiss Hotel, Ascend Hotel Collection
Curtiss Hotel, Ascend Hotel Collection
5 out of 5
210 Franklin St, Buffalo, NY
The price is $219 per night from May 12 to May 13
$219
per night
May 12 - May 13
Stay at this 5-star luxury hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the bar and the helpful staff in our reviews. ...
9/10 Wonderful! (1,002 reviews)
"Excellent service from the minute I drove into the parking lot. Check in, food service etc. clean gorgeous room"

Reviewed on May 11, 2024

Curtiss Hotel, Ascend Hotel Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Buffalo Hotels

Motel 6 Buffalo, NY - Airport - Williamsville
Motel 6 Buffalo, NY - Airport - Williamsville
2 out of 5
52 Freeman Rd, Buffalo, NY
The price is $72 per night from May 12 to May 13
$72
per night
May 12 - May 13
Stay at this motel in Buffalo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the clean rooms and the overall value in our reviews. ...
6.2/10 (1,001 reviews)
"Our stay was amazing."

Reviewed on Apr 10, 2024

Motel 6 Buffalo, NY - Airport - Williamsville
Red Roof Inn Buffalo - Niagara Airport
Red Roof Inn Buffalo - Niagara Airport
2 out of 5
146 Maple Drive, Bowmansville, NY
The price is $76 per night from May 22 to May 23
$76
per night
May 22 - May 23
Book a stay at this business-friendly hotel in Bowmansville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,003 reviews)
WONDERFUL!
"It was wonderful and we were serviced to the utmost. The only thing I would recommend is if you have scent allergies please phone ahead to make sure they do not spray the room with any cleaners, as they were pretty strong to breathe."

Reviewed on May 7, 2024

Red Roof Inn Buffalo - Niagara Airport
Red Roof Inn PLUS+ University at Buffalo - Amherst
Red Roof Inn PLUS+ University at Buffalo - Amherst
2.5 out of 5
42 Flint Rd, Buffalo, NY
Stay at this hotel in Buffalo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the clean rooms in our reviews. Popular attractions ...
5.8/10 (1,000 reviews)
"I like staff & services ."

Reviewed on Aug 19, 2023

Get rates
Red Roof Inn PLUS+ University at Buffalo - Amherst
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Buffalo

Sleep Inn & Suites Buffalo Airport
Sleep Inn & Suites Buffalo Airport
2.5 out of 5
100 Holtz Dr, Buffalo, NY
The price is $98 per night from May 13 to May 14
$98
per night
May 13 - May 14
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,108 reviews)

Families like: Skiing nearby, extra beds/cribs, free breakfast for the whole family, free airport shuttle

Travelers say...
"Great location for early airport travel"

Reviewed on May 6, 2024

Sleep Inn & Suites Buffalo Airport
Country Inn & Suites by Radisson, Buffalo South I-90, NY
Country Inn & Suites by Radisson, Buffalo South I-90, NY
2.5 out of 5
164b Slade Ave, Buffalo, NY
The price is $114 per night from May 19 to May 20
$114
per night
May 19 - May 20
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,075 reviews)

Families like: Indoor pools, skiing nearby, free breakfast for the whole family, laundry

Travelers say...
"Location was perfect"

Reviewed on May 8, 2024

Country Inn & Suites by Radisson, Buffalo South I-90, NY
Staybridge Suites Buffalo-Amherst, an IHG Hotel
Staybridge Suites Buffalo-Amherst, an IHG Hotel
3 out of 5
1290 Sweethome Rd, Buffalo, NY
The price is $152 per night from May 13 to May 14
$152
per night
May 13 - May 14
Stay at this 3-star business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,000 reviews)

Families like: Indoor pools, kitchen, free breakfast for the whole family, laundry

Travelers say...
"Great place to stay"

Reviewed on May 3, 2024

Staybridge Suites Buffalo-Amherst, an IHG Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Map To Nearby Hotels

TYS to BUF Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York
BUF Address & GPS
Address:
Genesee Street
Buffalo NY, 14225
United States
IATA Code:
BUF
Longitude:
-78.731804
Latitude:
42.933828
Time Zone:
America/New_York

Frequently asked questions

Am I able to catch a flight from Knoxville, TN Airport (TYS-McGhee Tyson) to Buffalo, NY Airport (BUF-Buffalo Niagara Intl.) now?
Check out our Covid-19 Travel Advisor for the most comprehensive info on quarantine and travel restrictions when getting a flight from Knoxville, TN Airport (TYS-McGhee Tyson) to Buffalo, NY Airport (BUF-Buffalo Niagara Intl.).
Are there non-stop flights from Knoxville Airport to Buffalo, NY Airport (BUF-Buffalo Niagara Intl.)?
Traveling from McGhee Tyson Airport (TYS) to Buffalo, NY Airport (BUF-Buffalo Niagara Intl.)? Breaking up the journey is your one and only option as there are currently no airlines that fly nonstop on this route. However, American Airlines, Delta and United Airlines offer the nearest thing — a flight with just one stopover.
What is the shortest flight from Knoxville Airport to BUF?
From Old City, the eclectic sights and sounds of Fort Erie are 3 hours and 39 minutes away. Be sure to book your favorite seat, or maybe even upgrade to one with a little more legroom, and get to your destination in comfort.
How many hours flight from Knoxville Airport to BUF?
From Knoxville, TN Airport (TYS-McGhee Tyson) to Buffalo Niagara Intl. Airport (BUF), you’ll be in your seat for roughly 3 hours and 47 minutes. Get cozy, order a wine and take out your noise-canceling earphones. It’s time to rewatch your favorite TV shows.
If I am not able to travel due to COVID-19, can I cancel my flight to Buffalo, NY Airport (BUF-Buffalo Niagara Intl.)?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Buffalo, NY Airport (BUF-Buffalo Niagara Intl.) have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to Buffalo, NY Airport (BUF-Buffalo Niagara Intl.) with flexible change policies?
In most cases you’ll have the option to reschedule your flight to Buffalo, NY Airport (BUF-Buffalo Niagara Intl.) without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What airlines have the most flights from Knoxville Airport to Buffalo, NY Airport (BUF-Buffalo Niagara Intl.)?
At the moment, there are no airlines that fly direct from McGhee Tyson Airport (TYS) to Buffalo Niagara Intl. Airport (BUF). But never fear. There are plenty of single or multi-stop flights available.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.