Cheap flights from RSW to DSM (Southwest Florida Intl. to Des Moines Intl.)

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Cheap Flights from RSW to DSM starting at $142 One Way, $356 Round Trip

Prices starting at $356 for return flights and $142 for one-way flights to Des Moines Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, May 24 - Sun, May 26
RSW
Fort Myers
DSM
Des Moines
$356 Roundtrip, found 3 days ago
$356
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, May 24 from Fort Myers to Des Moines, returning Sun, May 26, priced at $356 found 3 days ago
Fri, May 24 - Sun, May 26
RSW
Fort Myers
DSM
Des Moines
$374 Roundtrip, found 3 days ago
$374
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, May 24 from Fort Myers to Des Moines, returning Sun, May 26, priced at $374 found 3 days ago
Fri, May 24 - Sun, May 26
RSW
Fort Myers
DSM
Des Moines
$404 Roundtrip, found 3 days ago
$404
Roundtrip
found 3 days ago
Select United flight, departing Fri, May 24 from Fort Myers to Des Moines, returning Sun, May 26, priced at $404 found 3 days ago
Fri, May 24 - Sun, May 26
RSW
Fort Myers
DSM
Des Moines
$405 Roundtrip, found 3 days ago
$405
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, May 24 from Fort Myers to Des Moines, returning Sun, May 26, priced at $405 found 3 days ago
Fri, May 24 - Sun, May 26
RSW
Fort Myers
DSM
Des Moines
$409 Roundtrip, found 3 days ago
$409
Roundtrip
found 3 days ago
Select United flight, departing Fri, May 24 from Fort Myers to Des Moines, returning Sun, May 26, priced at $409 found 3 days ago

Hotel Ideas near Des Moines Intl.

Airport Hotels near Des Moines Intl.

Days Inn & Suites by Wyndham Des Moines Airport
Days Inn & Suites by Wyndham Des Moines Airport
2 out of 5
1901 Hackley Ave, Des Moines, IA
The price is $70 per night from May 12 to May 13
$70
per night
May 12 - May 13
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,136 reviews)
"Fast, easy check-in and proximity to airport"

Reviewed on May 9, 2024

Days Inn & Suites by Wyndham Des Moines Airport
Hampton Inn Des Moines-Airport
Hampton Inn Des Moines-Airport
2.5 out of 5
5001 Fleur Dr, Des Moines, IA
The price is $118 per night from May 26 to May 27
$118
per night
May 26 - May 27
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.4/10 Very Good! (1,003 reviews)
"Very nice"

Reviewed on May 9, 2024

Hampton Inn Des Moines-Airport
AmericInn by Wyndham Des Moines Airport
AmericInn by Wyndham Des Moines Airport
2.5 out of 5
1920 Hackley Ave, Des Moines, IA
The price is $71 per night from May 26 to May 27
$71
per night
May 26 - May 27
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.6/10 Good! (886 reviews)
"Just what we needed between flights."

Reviewed on May 1, 2024

AmericInn by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Des Moines

Quality Inn & Suites Des Moines - Merle Hay Road
Quality Inn & Suites Des Moines - Merle Hay Road
2.5 out of 5
4995 Merle Hay Rd, Des Moines, IA
The price is $63 per night from May 12 to May 13
$63
per night
May 12 - May 13
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (575 reviews)
Not great but not bad
"This hotel was average, I'd say. Not bad, not good. The windows on the highway side were thin & could hear the interstate. Walls were thin too and pillows were all feather so not a lot of support. Breakfast was decent."

Reviewed on May 6, 2024

Quality Inn & Suites Des Moines - Merle Hay Road
Stoney Creek Hotel Des Moines - Johnston
Stoney Creek Hotel Des Moines - Johnston
2.5 out of 5
5291 Stoney Creek Court, Johnston, IA
The price is $102 per night from May 26 to May 27
$102
per night
May 26 - May 27
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,134 reviews)
"Great place to stay, super clean. Beds and pillows were super comfortable. Breakfast smelled great, we left before it opened unfortunately. Pool looked cool as heck but we didn't have time to try it. Bar with a bit of food selection was great. Staff amazing."

Reviewed on May 7, 2024

Stoney Creek Hotel Des Moines - Johnston
Days Inn & Suites by Wyndham Des Moines Airport
Days Inn & Suites by Wyndham Des Moines Airport
2 out of 5
1901 Hackley Ave, Des Moines, IA
The price is $70 per night from May 12 to May 13
$70
per night
May 12 - May 13
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,136 reviews)
"Fast, easy check-in and proximity to airport"

Reviewed on May 9, 2024

Days Inn & Suites by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Des Moines Hotels With Airport Transportation

Days Inn & Suites by Wyndham Des Moines Airport
Days Inn & Suites by Wyndham Des Moines Airport
2 out of 5
1901 Hackley Ave, Des Moines, IA
The price is $70 per night from May 12 to May 13
$70
per night
May 12 - May 13
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,136 reviews)
"Fast, easy check-in and proximity to airport"

Reviewed on May 9, 2024

Days Inn & Suites by Wyndham Des Moines Airport
Quality Inn & Suites Des Moines Airport
Quality Inn & Suites Des Moines Airport
2.5 out of 5
5231 Fleur Dr, Des Moines, IA
The price is $70 per night from May 12 to May 13
$70
per night
May 12 - May 13
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (771 reviews)
"The girl at the front desk, her name was something like Celina, or close to that. She was the most wonderful, kind, and friendly person I have ever encountered at any motel, hotel or other place where it really counts to GREAT customer service. We stayed a total of 3 nights at your property. As we ..."

Reviewed on May 7, 2024

Quality Inn & Suites Des Moines Airport
Hampton Inn Des Moines-Airport
Hampton Inn Des Moines-Airport
2.5 out of 5
5001 Fleur Dr, Des Moines, IA
The price is $118 per night from May 26 to May 27
$118
per night
May 26 - May 27
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.4/10 Very Good! (1,003 reviews)
"Very nice"

Reviewed on May 9, 2024

Hampton Inn Des Moines-Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Des Moines Hotels

Days Inn by Wyndham West Des Moines
Days Inn by Wyndham West Des Moines
2 out of 5
1258 8th St, West Des Moines, IA
The price is $53 per night from May 19 to May 20
$53
per night
May 19 - May 20
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
5.8/10 (1,002 reviews)
"It had warm breakfast& was bestmotel for 65 bucks that ive ever rented. Was hair better then rest in same category"

Reviewed on May 8, 2024

Days Inn by Wyndham West Des Moines
Motel 6 West Des Moines, IA
Motel 6 West Des Moines, IA
2 out of 5
7655 Office Plaza Dr N, West Des Moines, IA
The price is $68 per night from May 12 to May 13
$68
per night
May 12 - May 13
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
6.8/10 (1,003 reviews)
"The staff very helpful."

Reviewed on May 7, 2024

Motel 6 West Des Moines, IA
Cozy Rest Motel
Cozy Rest Motel
2 out of 5
2316 Southeast 14th Street, Des Moines, IA
The price is $74 per night from May 12 to May 13
$74
per night
May 12 - May 13
Stay at this motel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (549 reviews)
"Had a nice stay. The facility is close to a busy road so I heard the traffic very early but that isn't the facilities fault. Clean and the staff was helpful and nice"

Reviewed on Apr 6, 2024

Cozy Rest Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Ramada Tropics Resort & Conf Center by Wyndham Des Moines
3 out of 5
5000 Merle Hay Rd, Urbandale, IA
The price is $94 per night from May 12 to May 13
$94
per night
May 12 - May 13
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.4/10 (1,003 reviews)

Families like: Indoor pools, waterpark, game room, extra beds/cribs

Travelers say...
"Good"

Reviewed on Apr 18, 2024

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Wildwood Lodge
Wildwood Lodge
3 out of 5
11431 Forest Ave, Clive, IA
The price is $98 per night from May 13 to May 14
$98
per night
May 13 - May 14
Stay at this 3-star hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions ...
9.4/10 Exceptional! (1,367 reviews)

Families like: Indoor pools, free breakfast for the whole family, laundry

Travelers say...
"We always like to stay at the wildwood Lodge. It’s clean affordable, and the staff are always helpful and friendly."

Reviewed on May 10, 2024

Wildwood Lodge
Baymont by Wyndham Des Moines Airport
Baymont by Wyndham Des Moines Airport
2.5 out of 5
6221 Willow Creek Ave, Des Moines, IA
The price is $98 per night from May 27 to May 28
$98
per night
May 27 - May 28
Book a stay at this golf hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. ...
9.4/10 Exceptional! (1,004 reviews)

Families like: Indoor pools, game room, extra beds/cribs, games and toys

I will come back.
"Ladies at front desk were so kind and helpful. Room was clean and comfortable. Highly recommend."

Reviewed on May 8, 2024

Baymont by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Map To Nearby Hotels

RSW to DSM Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
RSW Address & GPS
Address:
11000 Terminal Access Road
Fort Myers FL,
United States
IATA Code:
RSW
Longitude:
-81.755263
Latitude:
26.527887
Time Zone:
America/New_York
DSM Address & GPS
Address:
5800 Fleur Drive, Suite 201
Des Moines IA, 50321-2854
United States
IATA Code:
DSM
Longitude:
-93.648087
Latitude:
41.532434
Time Zone:
America/Chicago

Frequently asked questions

Am I able to catch a flight from Fort Myers, FL Airport (RSW-Southwest Florida Intl.) to Des Moines, IA Airport (DSM-Des Moines Intl.) now?
Go right to our Covid-19 Travel Advisor for the most up-to-date information on travel restrictions and quarantine when flying from Fort Myers, FL Airport (RSW-Southwest Florida Intl.) to Des Moines, IA Airport (DSM-Des Moines Intl.).
Are there non-stop flights from Southwest Florida Intl. Airport to Des Moines Intl. Airport (DSM)?
You’ll need to switch planes if you’re wanting to travel from Fort Myers, FL Airport (RSW-Southwest Florida Intl.) to Des Moines Intl. Airport. Several airlines offer services on this route with only one stopover, including American Airlines, Delta and United Airlines.
What is the shortest flight from Fort Myers, FL Airport (RSW-Southwest Florida Intl.) to Des Moines Intl. Airport?
Traveling from Fort Myers, FL Airport (RSW-Southwest Florida Intl.) to DSM takes at least 4 hours and 34 minutes. Enjoy a wine and watch a flick or two — this is a great opportunity to sit back and unwind.
How many hours flight from Southwest Florida Intl. Airport (RSW) to DSM?
Typically, the journey from Southwest Florida Intl. Airport to Des Moines, IA Airport (DSM-Des Moines Intl.) takes 4 hours and 40 minutes. If you want to be as comfy as possible, try upgrading your seat using miles or cash.
If I am not able to travel due to COVID-19, can I cancel my flight to Des Moines, IA Airport (DSM-Des Moines Intl.)?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Des Moines, IA Airport (DSM-Des Moines Intl.) have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to Des Moines, IA Airport (DSM-Des Moines Intl.) with flexible change policies?
In most cases you’ll have the option to reschedule your flight to Des Moines, IA Airport (DSM-Des Moines Intl.) without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What airlines have the most flights from Southwest Florida Intl. Airport (RSW) to Des Moines, IA Airport (DSM-Des Moines Intl.)?
There are no airlines flying direct from Fort Myers, FL Airport (RSW-Southwest Florida Intl.) to Des Moines, IA Airport (DSM-Des Moines Intl.). Do your research and secure a multi or single-stop plane ticket.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.