Cheap flights from MSY to TYS (Louis Armstrong New Orleans Intl. to McGhee Tyson)

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Cheap Flights from MSY to TYS starting at $100 One Way, $227 Round Trip

Prices starting at $227 for return flights and $100 for one-way flights to McGhee Tyson were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, May 30 - Tue, Jun 3
MSY
New Orleans
TYS
Knoxville
$227 Roundtrip, found 7 hours ago
$227
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Fri, May 30 from New Orleans to Knoxville, returning Tue, Jun 3, priced at $227 found 7 hours ago
Sat, May 24 - Mon, May 26
MSY
New Orleans
TYS
Knoxville
$233 Roundtrip, found 5 hours ago
$233
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, May 24 from New Orleans to Knoxville, returning Mon, May 26, priced at $233 found 5 hours ago
Fri, May 30 - Tue, Jun 3
MSY
New Orleans
TYS
Knoxville
$237 Roundtrip, found 7 hours ago
$237
Roundtrip
found 7 hours ago
Select Delta flight, departing Fri, May 30 from New Orleans to Knoxville, returning Tue, Jun 3, priced at $237 found 7 hours ago
Fri, May 30 - Tue, Jun 3
MSY
New Orleans
TYS
Knoxville
$237 Roundtrip, found 7 hours ago
$237
Roundtrip
found 7 hours ago
Select Delta flight, departing Fri, May 30 from New Orleans to Knoxville, returning Tue, Jun 3, priced at $237 found 7 hours ago
Tue, May 20 - Thu, May 29
MSY
New Orleans
TYS
Knoxville
$242 Roundtrip, found 4 days ago
$242
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, May 20 from New Orleans to Knoxville, returning Thu, May 29, priced at $242 found 4 days ago

Hotel Ideas near McGhee Tyson

Airport Hotels near McGhee Tyson

Hilton Knoxville Airport
Hilton Knoxville Airport
3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
The price is $187 per night from May 23 to May 24
$187
includes taxes & fees
$158 per night
May 23 - May 24
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,001 reviews)
"Quiet area, comfortable beds, clean rooms, easy check in, friendly staff."

Reviewed on Apr 27, 2025

Hilton Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport
2.5 out of 5
126 Cusick Road, Alcoa, TN
The price is $108 per night from May 11 to May 12
$108
includes taxes & fees
$91 per night
May 11 - May 12
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,417 reviews)
"This hotel is conveniently located to the airport. The rooms were clean, bed were comfortable and the staff was friendly."

Reviewed on May 5, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Best Western Knoxville Airport/Alcoa
Best Western Knoxville Airport/Alcoa
2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $96 per night from May 10 to May 11
$96
includes taxes & fees
$81 per night
May 10 - May 11
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,001 reviews)
"Very close to airport and shuttle service was great. Hotel was very clean and friendly staff. Breakfast was good, omlets sausage,breads, and cereals. Only downer was my room was next to a pump or something that went on and off with an extremely loud hum."

Reviewed on Apr 27, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Knoxville

La Quinta Inn & Suites by Wyndham Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport
2.5 out of 5
126 Cusick Road, Alcoa, TN
The price is $108 per night from May 11 to May 12
$108
includes taxes & fees
$91 per night
May 11 - May 12
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,417 reviews)
"This hotel is conveniently located to the airport. The rooms were clean, bed were comfortable and the staff was friendly."

Reviewed on May 5, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport
Hilton Knoxville Airport
3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
The price is $187 per night from May 23 to May 24
$187
includes taxes & fees
$158 per night
May 23 - May 24
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,001 reviews)
"Quiet area, comfortable beds, clean rooms, easy check in, friendly staff."

Reviewed on Apr 27, 2025

Hilton Knoxville Airport
Best Western Knoxville Airport/Alcoa
Best Western Knoxville Airport/Alcoa
2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $96 per night from May 10 to May 11
$96
includes taxes & fees
$81 per night
May 10 - May 11
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,001 reviews)
"Very close to airport and shuttle service was great. Hotel was very clean and friendly staff. Breakfast was good, omlets sausage,breads, and cereals. Only downer was my room was next to a pump or something that went on and off with an extremely loud hum."

Reviewed on Apr 27, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Knoxville Hotels With Airport Transportation

La Quinta Inn & Suites by Wyndham Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport
2.5 out of 5
126 Cusick Road, Alcoa, TN
The price is $108 per night from May 11 to May 12
$108
includes taxes & fees
$91 per night
May 11 - May 12
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,417 reviews)
"This hotel is conveniently located to the airport. The rooms were clean, bed were comfortable and the staff was friendly."

Reviewed on May 5, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
USA Inn
USA Inn
3 out of 5
Alcoa Hwy, 2962, Alcoa, TN
The price is $70 per night from May 7 to May 8
$70
includes taxes & fees
$59 per night
May 7 - May 8
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (699 reviews)
"Ac was great, they have a minor roach and prostitution issue, couldn’t sleep without hearing them “working” or waiting outside for people every night."

Reviewed on Oct 6, 2024

USA Inn
Best Western Knoxville Airport/Alcoa
Best Western Knoxville Airport/Alcoa
2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $96 per night from May 10 to May 11
$96
includes taxes & fees
$81 per night
May 10 - May 11
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,001 reviews)
"Very close to airport and shuttle service was great. Hotel was very clean and friendly staff. Breakfast was good, omlets sausage,breads, and cereals. Only downer was my room was next to a pump or something that went on and off with an extremely loud hum."

Reviewed on Apr 27, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Knoxville Hotels

USA Inn
USA Inn
3 out of 5
Alcoa Hwy, 2962, Alcoa, TN
The price is $70 per night from May 7 to May 8
$70
includes taxes & fees
$59 per night
May 7 - May 8
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Meigs Falls and Fort Loudoun ...
5/10 (699 reviews)
"Ac was great, they have a minor roach and prostitution issue, couldn’t sleep without hearing them “working” or waiting outside for people every night."

Reviewed on Oct 6, 2024

USA Inn
Candlewood Suites Knoxville Airport-Alcoa by IHG
Candlewood Suites Knoxville Airport-Alcoa by IHG
2.5 out of 5
176 Cusick Road, Alcoa, TN
The price is $133 per night from May 26 to May 27
$133
includes taxes & fees
$112 per night
May 26 - May 27
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Meigs Falls and Palace Theater ...
8.2/10 Very Good! (539 reviews)
"Solid spot to stay near the airport"

Reviewed on Apr 25, 2025

Candlewood Suites Knoxville Airport-Alcoa by IHG
Best Western Knoxville Airport/Alcoa
Best Western Knoxville Airport/Alcoa
2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $96 per night from May 10 to May 11
$96
includes taxes & fees
$81 per night
May 10 - May 11
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,001 reviews)
"Very close to airport and shuttle service was great. Hotel was very clean and friendly staff. Breakfast was good, omlets sausage,breads, and cereals. Only downer was my room was next to a pump or something that went on and off with an extremely loud hum."

Reviewed on Apr 27, 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Knoxville

Comfort Suites Knoxville Airport
Comfort Suites Knoxville Airport
2.5 out of 5
140 Cusick Rd, Alcoa, TN
The price is $105 per night from Jun 1 to Jun 2
$105
includes taxes & fees
$88 per night
Jun 1 - Jun 2
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (669 reviews)
"Nice"

Reviewed on May 4, 2025

Comfort Suites Knoxville Airport
Best Western Knoxville Airport/Alcoa
Best Western Knoxville Airport/Alcoa
2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is $96 per night from May 10 to May 11
$96
includes taxes & fees
$81 per night
May 10 - May 11
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,001 reviews)
"Very close to airport and shuttle service was great. Hotel was very clean and friendly staff. Breakfast was good, omlets sausage,breads, and cereals. Only downer was my room was next to a pump or something that went on and off with an extremely loud hum."

Reviewed on Apr 27, 2025

Best Western Knoxville Airport/Alcoa
La Quinta Inn & Suites by Wyndham Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport
2.5 out of 5
126 Cusick Road, Alcoa, TN
The price is $108 per night from May 11 to May 12
$108
includes taxes & fees
$91 per night
May 11 - May 12
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,417 reviews)
"This hotel is conveniently located to the airport. The rooms were clean, bed were comfortable and the staff was friendly."

Reviewed on May 5, 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MSY to TYS Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
MSY Address & GPS
Address:
900 Airline Highway
New Orleans LA, 70062
United States
IATA Code:
MSY
Longitude:
-90.256391
Latitude:
29.984564
Time Zone:
America/Chicago
TYS Address & GPS
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA Code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time Zone:
America/New_York

Frequently asked questions

Am I able to catch a flight from New Orleans, LA Airport (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN Airport (TYS-McGhee Tyson) now?
If you’re baffled about quarantine and travel restrictions when traveling by plane from New Orleans, LA Airport (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN Airport (TYS-McGhee Tyson), check out our Covid-19 Travel Advisor.
Are there non-stop flights from Louis Armstrong New Orleans Intl. Airport (MSY) to McGhee Tyson Airport (TYS)?
Flying from New Orleans, LA Airport (MSY-Louis Armstrong New Orleans Intl.) to McGhee Tyson Airport (TYS) means you’ll have to swap planes. But hey — there’s no need to worry. American Airlines, United Airlines and Delta offer flights with just a single stopover.
What is the shortest flight from Louis Armstrong New Orleans Intl. Airport (MSY) to Knoxville Airport?
From Holy Cross District, the distinctive sights and sounds of Old City are 4 hours and 8 minutes away. Be sure to book your favorite seat, or perhaps even upgrade to one with a bit more legroom, and get to your destination in comfort.
How many hours flight from Louis Armstrong New Orleans Intl. Airport to TYS?
From Louis Armstrong New Orleans Intl. Airport (MSY) to Knoxville Airport, you’ll be in your seat for an average of 4 hours and 13 minutes. Settle in, order a wine and put on your noise-canceling headphones. It’s time for a binge-watching session.
If I am not able to travel due to COVID-19, can I cancel my flight to Knoxville, TN Airport (TYS-McGhee Tyson)?
We get that traveling right now has its challenges, so it’s good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to Knoxville, TN Airport (TYS-McGhee Tyson) have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you’ll quickly see what options are available. Our Customer Service Portal is the place to go for more information.
Are there flights to Knoxville, TN Airport (TYS-McGhee Tyson) with flexible change policies?
In most cases you’ll have the option to reschedule your flight to Knoxville, TN Airport (TYS-McGhee Tyson) without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the “no change fees” filter and book with confidence.
What airlines have the most flights from Louis Armstrong New Orleans Intl. Airport to Knoxville Airport?
Right now, there are no airlines that offer direct flights between New Orleans, LA Airport (MSY-Louis Armstrong New Orleans Intl.) and TYS. But don’t panic! There are numerous single or multi-stop options available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.