Cheap flights from MDT to BRU (Harrisburg Intl. to Brussels - National)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Cheap Flights from MDT to BRU starting at $334 One Way, $831 Round Trip
Prices starting at $831 for return flights and $334 for one-way flights to Brussels - National were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
MDT
Harrisburg
BRU
Brussels
$831 Roundtrip, found 4 days ago
$831
Roundtrip
found 4 days ago
MDT
Harrisburg
BRU
Brussels
$1,005 Roundtrip, found 4 days ago
$1,005
Roundtrip
found 4 days ago
MDT
Harrisburg
BRU
Brussels
$1,025 Roundtrip, found 4 days ago
$1,025
Roundtrip
found 4 days ago
MDT
Harrisburg
BRU
Brussels
$1,030 Roundtrip, found 4 days ago
$1,030
Roundtrip
found 4 days ago
MDT
Harrisburg
BRU
Brussels
$1,035 Roundtrip, found 4 days ago
$1,035
Roundtrip
found 4 days ago
Hotel Ideas near Brussels - National
Airport Hotels near Brussels - National
Sheraton Brussels Airport Hotel
Brussels National Airport Zaventem
$152 nightly
The price is $183 total per night from Nov 13 to Nov 14
$183 total
Nov 13 - Nov 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Zaventem. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
8.8/10 Excellent! (1,245 reviews)
"Few step to Airport terminal. Great for travel."
Reviewed on Nov 1, 2026
B&B HOTEL Brussels Airport
WOLUWELAAN 140 Machelen
$67 nightly
The price is $82 total per night from Nov 6 to Nov 7
$82 total
Nov 6 - Nov 7
Total with taxes and fees
Stay at this hotel in Machelen. Enjoy breakfast (surcharge), parking (surcharge), and a 24-hour front desk. Popular attractions La Grand Place and Atomium are ...
Hilton Garden Inn Brussels Airport
Culliganlaan 3A,bus00 1831 Diegem Machelen BRU
$88 nightly
The price is $105 total per night from Nov 22 to Nov 23
$105 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions La Grand Place and Atomium ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Brussels
Warwick Brussels Grand-Place
Rue Duquesnoy 5-7 Brussels
$130 nightly
The price is $151 total per night from Nov 15 to Nov 16
$151 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this family-friendly hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
9/10 Wonderful! (1,916 reviews)
"It is in the center of the Brussels and just a walking distance from the train station. Lots of dining options nearby. The room is nice and the staffs are friendly. It is also pretty quiet from the street. But we can hear some talks from next door, not sure whether it is from a loud neighbor."
Reviewed on Nov 2, 2026
Thon Hotel EU
Rue de la Loi, 75 Brussels
$125 nightly
The price is $146 total per night from Nov 13 to Nov 14
$146 total
Nov 13 - Nov 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
Motel One Brussels
Rue Royale 120 Brussels
$108 nightly
The price is $127 total per night from Nov 8 to Nov 9
$127 total
Nov 8 - Nov 9
Total with taxes and fees
Stay at this hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the bar and the helpful staff in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Brussels Hotels With Airport Transportation
Novotel Brussels Airport
Da vinci laan 25 Machelen Flemish Brabant
$93 nightly
The price is $110 total per night from Nov 22 to Nov 23
$110 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this family-friendly hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.6/10 Excellent! (1,004 reviews)
"Très bien. ……je n’aime pas à être forcée d’écrire pour que je puisse revenir à consulter m9n compte!"
Reviewed on Oct 31, 2026
ibis budget Brussels Airport
Bessenveldstraat Machelen
$53 nightly
The price is $65 total per night from Nov 29 to Nov 30
$65 total
Nov 29 - Nov 30
Total with taxes and fees
Stay at this hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our ...
7.4/10 Good! (1,001 reviews)
"Difficult location to access local amenities from"
Reviewed on Nov 1, 2026
ibis Brussels Airport
Bessenveldstraat 17 Machelen
$67 nightly
The price is $82 total per night from Nov 6 to Nov 7
$82 total
Nov 6 - Nov 7
Total with taxes and fees
Stay at this hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the property condition in our reviews. Popular ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Brussels Hotels
easyHotel Brussels City Centre
Zilverstraat 1 Brussels
$76 nightly
The price is $91 total per night from Nov 8 to Nov 9
$91 total
Nov 8 - Nov 9
Total with taxes and fees
Stay at this hotel in Brussels. Enjoy free WiFi, a 24-hour front desk, and memory foam beds. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.4/10 Very Good! (1,005 reviews)
"We enjoyed our stay here at easy hotel. The hotel itself is very well maintained, clean, and the staff are very kind and helpful. Very close to all the restaurants, train station, and all tourist attractions lije the grand place, the bus uses and shopping malls."
Reviewed on Nov 1, 2026
ibis budget Brussels Airport
Bessenveldstraat Machelen
$53 nightly
The price is $65 total per night from Nov 29 to Nov 30
$65 total
Nov 29 - Nov 30
Total with taxes and fees
Stay at this hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our ...
7.4/10 Good! (1,001 reviews)
"Difficult location to access local amenities from"
Reviewed on Nov 1, 2026
Bedford Hotel & Congress Centre
Rue Du Midi 135 Brussels
$100 nightly
The price is $118 total per night from Nov 8 to Nov 9
$118 total
Nov 8 - Nov 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the breakfast and the ...
8.4/10 Very Good! (1,004 reviews)
"The hotel is so central to walk to everywhere. Just 500m from Grand Place. The roof top bar is a must for views, lovely drinks and a great meal. All the staff were so attentive and gave good service. Will always stay here if visiting Brussels again"
Reviewed on Oct 31, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Brussels
Novotel Brussels City Centre
Rue De La Vierge Noire 32 Brussels
$124 nightly
The price is $145 total per night from Nov 22 to Nov 23
$145 total
Nov 22 - Nov 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
9/10 Wonderful! (1,003 reviews)
"Good hotel, brilliant location."
Reviewed on Nov 2, 2026
Novotel Brussels off Grand'Place
120 Rue Du Marche Aux Herbes Brussels
$166 nightly
The price is $193 total per night from Nov 22 to Nov 23
$193 total
Nov 22 - Nov 23
Total with taxes and fees
Stay at this hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
MDT to BRU Route Info
Origin Airport | |
|---|---|
Destination Airport | |
Number Of Airlines Serving | |
Distance | |
Shortest Flight Departure Time | |
Shortest Flight Departure Date |
- Airport Locations
- More Popular Flights
- Top Trending
- Flights from Other Cities
- Flights From Other Airports
MDT Address & GPS
Address:
One Terminal Drive
Middletown PA, 17057
United States
IATA Code:
MDT
Longitude:
-76.756057
Latitude:
40.196008
Time Zone:
America/New_York
BRU Address & GPS
Address:
Brussels ,
Belgium
IATA Code:
BRU
Longitude:
4.483602
Latitude:
50.89717
Time Zone:
Europe/Brussels
Other Flights from Harrisburg Intl. Airport (MDT)
Other Flights to Brussels - National Airport (BRU)
Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.