Cheap flights from MDT to BRU (Harrisburg Intl. to Brussels - National)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from MDT to BRU starting at $378 One Way, $809 Round Trip

Prices starting at $809 for return flights and $378 for one-way flights to Brussels - National were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Feb 12 - Fri, Feb 19
MDT
Harrisburg
BRU
Brussels
$809 Roundtrip, found 1 day ago
$809
Roundtrip
found 1 day ago
Select British Airways flight, departing Fri, Feb 12 from Harrisburg to Brussels, returning Fri, Feb 19, priced at $809 found 1 day ago
Fri, Feb 12 - Fri, Feb 19
MDT
Harrisburg
BRU
Brussels
$859 Roundtrip, found 1 day ago
$859
Roundtrip
found 1 day ago
Select British Airways flight, departing Fri, Feb 12 from Harrisburg to Brussels, returning Fri, Feb 19, priced at $859 found 1 day ago
Fri, Feb 12 - Fri, Feb 19
MDT
Harrisburg
BRU
Brussels
$882 Roundtrip, found 1 day ago
$882
Roundtrip
found 1 day ago
Select British Airways flight, departing Fri, Feb 12 from Harrisburg to Brussels, returning Fri, Feb 19, priced at $882 found 1 day ago
Fri, Feb 12 - Fri, Feb 19
MDT
Harrisburg
BRU
Brussels
$928 Roundtrip, found 1 day ago
$928
Roundtrip
found 1 day ago
Select British Airways flight, departing Fri, Feb 12 from Harrisburg to Brussels, returning Fri, Feb 19, priced at $928 found 1 day ago
Sun, Nov 29 - Sun, Dec 6
MDT
Harrisburg
BRU
Brussels
$941 Roundtrip, found 4 days ago
$941
Roundtrip
found 4 days ago
Select British Airways flight, departing Sun, Nov 29 from Harrisburg to Brussels, returning Sun, Dec 6, priced at $941 found 4 days ago

Hotel Ideas near Brussels - National

Airport Hotels near Brussels - National

Sheraton Brussels Airport Hotel

Sheraton Brussels Airport Hotel

4 out of 5
Brussels National Airport Zaventem
$144 nightly
The price is $175 total per night from Oct 31 to Nov 1
$175 total
Oct 31 - Nov 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Zaventem. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
8.8/10 Excellent! (1,249 reviews)
"The two Turkish workers were the best one at lounge one at bar Both made all efforts to accommodate busy gathering Salute to both can’t recall names unfortunately"

Reviewed on Oct 19, 2026

Sheraton Brussels Airport Hotel
B&B HOTEL Brussels Airport

B&B HOTEL Brussels Airport

3 out of 5
WOLUWELAAN 140 Machelen
$64 nightly
The price is $79 total per night from Nov 13 to Nov 14
$79 total
Nov 13 - Nov 14
Total with taxes and fees
Stay at this hotel in Machelen. Enjoy breakfast (surcharge), parking (surcharge), and a 24-hour front desk. Popular attractions Atomium and Brussels Christmas ...
B&B HOTEL Brussels Airport
Hilton Garden Inn Brussels Airport

Hilton Garden Inn Brussels Airport

Culliganlaan 3A,bus00 1831 Diegem Machelen BRU
$89 nightly
The price is $106 total per night from Oct 31 to Nov 1
$106 total
Oct 31 - Nov 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Atomium and Brussels Christmas ...
Hilton Garden Inn Brussels Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Brussels

Warwick Brussels Grand-Place

Warwick Brussels Grand-Place

4 out of 5
Rue Duquesnoy 5-7 Brussels
$129 nightly
The price is $150 total per night from Nov 1 to Nov 2
$150 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this family-friendly hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
9/10 Wonderful! (1,892 reviews)
"Excellent location! Comfortable bed! Helpful staff! Free bottle of wine! All was great!"

Reviewed on Oct 19, 2026

Warwick Brussels Grand-Place
Thon Hotel EU

Thon Hotel EU

4 out of 5
Rue de la Loi, 75 Brussels
$139 nightly
The price is $163 total per night from Oct 24 to Oct 25
$163 total
Oct 24 - Oct 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
9.4/10 Exceptional! (1,005 reviews)
"We enjoyed the Thon Hotel, especially the little bed tucked way for the third guest. Very clean, comfortable beds, easy transport and nearby food."

Reviewed on Oct 18, 2026

Thon Hotel EU
Hotel Indigo Brussels - City by IHG

Hotel Indigo Brussels - City by IHG

Place Charles Rogier 20 Brussels
$138 nightly
The price is $161 total per night from Nov 1 to Nov 2
$161 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Hotel Indigo Brussels - City by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Brussels Hotels With Airport Transportation

Novotel Brussels Airport

Novotel Brussels Airport

3.5 out of 5
Da vinci laan 25 Machelen Flemish Brabant
$93 nightly
The price is $111 total per night from Nov 6 to Nov 7
$111 total
Nov 6 - Nov 7
Total with taxes and fees
Book a stay at this family-friendly hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
Novotel Brussels Airport
ibis budget Brussels Airport

ibis budget Brussels Airport

1 out of 5
Bessenveldstraat Machelen
$53 nightly
The price is $65 total per night from Nov 8 to Nov 9
$65 total
Nov 8 - Nov 9
Total with taxes and fees
Stay at this hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our ...
ibis budget Brussels Airport
ibis Brussels Airport

ibis Brussels Airport

3 out of 5
Bessenveldstraat 17 Machelen
$72 nightly
The price is $87 total per night from Nov 6 to Nov 7
$87 total
Nov 6 - Nov 7
Total with taxes and fees
Stay at this hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the property condition in our reviews. Popular ...
ibis Brussels Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Brussels Hotels

easyHotel Brussels City Centre

easyHotel Brussels City Centre

Zilverstraat 1 Brussels
$85 nightly
The price is $101 total per night from Nov 1 to Nov 2
$101 total
Nov 1 - Nov 2
Total with taxes and fees
Stay at this hotel in Brussels. Enjoy free WiFi, a 24-hour front desk, and memory foam beds. Our guests praise the helpful staff and the clean rooms in our reviews. ...
easyHotel Brussels City Centre
ibis budget Brussels Airport

ibis budget Brussels Airport

1 out of 5
Bessenveldstraat Machelen
$53 nightly
The price is $65 total per night from Nov 8 to Nov 9
$65 total
Nov 8 - Nov 9
Total with taxes and fees
Stay at this hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our ...
ibis budget Brussels Airport
Bedford Hotel & Congress Centre

Bedford Hotel & Congress Centre

3.5 out of 5
Rue Du Midi 135 Brussels
$104 nightly
The price is $122 total per night from Nov 8 to Nov 9
$122 total
Nov 8 - Nov 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the breakfast and the ...
Bedford Hotel & Congress Centre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Brussels

Novotel Brussels City Centre

Novotel Brussels City Centre

4 out of 5
Rue De La Vierge Noire 32 Brussels
$125 nightly
The price is $147 total per night from Nov 1 to Nov 2
$147 total
Nov 1 - Nov 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
9/10 Wonderful! (1,002 reviews)
"The hotel is fantastic ,the breakfast so good ,the clean room perfect ,the staff very friendly ,the hotel are in the city center near of everything ,very secure the zone ,excellent all ,my husband and me are very satisfied ."

Reviewed on Oct 18, 2026

Novotel Brussels City Centre
Novotel Brussels off Grand'Place

Novotel Brussels off Grand'Place

4 out of 5
120 Rue Du Marche Aux Herbes Brussels
$160 nightly
The price is $185 total per night from Nov 8 to Nov 9
$185 total
Nov 8 - Nov 9
Total with taxes and fees
Stay at this hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Novotel Brussels off Grand'Place
Meininger

Meininger

33 Quai du Hainaut / Henegouwenkaai Brussels Brussels-Capital Region
Stay at this hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Popular attractions Brussels Christmas Market and La Grand Place ...
Get rates
Meininger
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MDT to BRU Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

What is the shortest flight from MDT to Brussels Airport?
With the quickest flight time from Harrisburg Intl. Airport (MDT) to Brussels - National Airport (BRU) being 9 hours and 20 minutes, it's smart to have some in-flight survival tricks up your sleeve. An eye-mask, a neck pillow and earplugs should be among the essentials you put in your hand luggage.
How many hours flight from Harrisburg Intl. Airport (MDT) to BRU?
The trip from MDT to Brussels Airport typically lasts about 9 hours and 21 minutes. Make this long-haul flight go by a little faster by bringing your laptop full of your favorite flicks.
What airlines have the most flights from Harrisburg Intl. Airport (MDT) to BRU?
Watch the planes take off and land, grab a glazed doughnut, stretch your legs … Airport stopovers don't have to be boring! If you're planning to head from Harrisburg Intl. Airport to Brussels Airport, you can't fly direct. Be prepared for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.