Cheap flights from IAD to FLO (Washington Dulles Intl. to Florence Regional)

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Cheap Flights from IAD to FLO starting at $448 One Way, $224 Round Trip

Prices starting at $224 for return flights and $448 for one-way flights to Florence Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Jan 16 - Sun, Jan 18
IAD
Washington
FLO
Florence
$224 Roundtrip, found 5 days ago
$224
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Jan 16 from Washington to Florence, returning Sun, Jan 18, priced at $224 found 5 days ago
Fri, Jan 16 - Sun, Jan 18
IAD
Washington
FLO
Florence
$284 Roundtrip, found 5 days ago
$284
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Jan 16 from Washington to Florence, returning Sun, Jan 18, priced at $284 found 5 days ago
Fri, Jan 16 - Sun, Jan 18
IAD
Washington
FLO
Florence
$343 Roundtrip, found 5 days ago
$343
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Jan 16 from Washington to Florence, returning Sun, Jan 18, priced at $343 found 5 days ago
Thu, Feb 5 - Sat, Feb 7
IAD
Washington
FLO
Florence
$351 Roundtrip, found 4 days ago
$351
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Feb 5 from Washington to Florence, returning Sat, Feb 7, priced at $351 found 4 days ago
Fri, Jan 16 - Sun, Jan 18
IAD
Washington
FLO
Florence
$358 Roundtrip, found 5 days ago
$358
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Jan 16 from Washington to Florence, returning Sun, Jan 18, priced at $358 found 5 days ago

Hotel Ideas near Florence Regional

Airport Hotels near Florence Regional

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
$100 nightly
The price is $112 total per night from Jan 12 to Jan 13
$112 total
Jan 12 - Jan 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,003 reviews)
N/A

Reviewed on Jan 1, 2026

Hyatt Place Florence Downtown
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3 out of 5
126 W Evans St Florence SC
$130 nightly
The price is $146 total per night from Jan 11 to Jan 12
$146 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (609 reviews)
Very nice facility; lots of character. Convenient parking. Good breakfast. Very pleasant staff. Would definitely return.

Reviewed on Dec 23, 2025

Hotel Florence, Tapestry Collection by Hilton
Walking distance from one of South Carolina's top Medical centers.

Walking distance from one of South Carolina's top Medical centers.

Florence SC
$204 nightly
The price is $229 total per night from Jan 5 to Jan 6
$229 total
Jan 5 - Jan 6
Total with taxes and fees
Stay at this vacation home in Florence. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Old Greenwood Athletic Park and Drs Bruce and ...
9.8/10 Exceptional! (41 reviews)
Everything was great!

Reviewed on Nov 10, 2025

Walking distance from one of South Carolina's top Medical centers.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Florence

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
$70 nightly
The price is $79 total per night from Jan 4 to Jan 5
$79 total
Jan 4 - Jan 5
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,520 reviews)
Overall good experience.

Reviewed on Jan 1, 2026

Howard Johnson by Wyndham Florence
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
$98 nightly
The price is $110 total per night from Jan 18 to Jan 19
$110 total
Jan 18 - Jan 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,191 reviews)
Fast check in, comfortable bed, quiet setting and a wonderful breakfast.

Reviewed on Jan 2, 2026

Comfort Inn & Suites Florence Center Area
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
$85 nightly
The price is $95 total per night from Jan 11 to Jan 12
$95 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (2,226 reviews)
Nice hotel

Reviewed on Jan 2, 2026

Park Inn by Radisson Florence, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Florence Hotels

Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2 out of 5
2690 David H McLeod Boulevard Florence SC
$56 nightly
The price is $63 total per night from Jan 6 to Jan 7
$63 total
Jan 6 - Jan 7
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.6/10 (1,001 reviews)
room was decent

Reviewed on Nov 23, 2025

Red Roof Inn Florence - Civic Center
Budget Inn Timmonsville

Budget Inn Timmonsville

2 out of 5
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from Jan 4 to Jan 5
$68 total
Jan 4 - Jan 5
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (321 reviews)
very clean

Reviewed on Oct 16, 2025

Budget Inn Timmonsville
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$67 nightly
The price is $75 total per night from Jan 5 to Jan 6
$75 total
Jan 5 - Jan 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,001 reviews)
Receptionist was very professional and polite. And took her time to answer every question.

Reviewed on Jan 1, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Florence

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

3 out of 5
900 Woody Jones Blvd Florence SC
$106 nightly
The price is $118 total per night from Jan 11 to Jan 12
$118 total
Jan 11 - Jan 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,007 reviews)
We came for a hockey game, which was amazingly right across the street! Beautiful, spacious room at an amazing price. Couldn’t have asked for better accommodations. Thank you!

Reviewed on Dec 30, 2025

Home2 Suites by Hilton Florence, SC
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
$100 nightly
The price is $112 total per night from Jan 12 to Jan 13
$112 total
Jan 12 - Jan 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (31 reviews)
Yes

Reviewed on Dec 28, 2025

Spark by Hilton Florence North I-95, SC
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$67 nightly
The price is $75 total per night from Jan 5 to Jan 6
$75 total
Jan 5 - Jan 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,001 reviews)
Receptionist was very professional and polite. And took her time to answer every question.

Reviewed on Jan 1, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

IAD to FLO Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

What is the shortest flight from Dulles Intl. Airport to FLO?
It can take merely 2 hours and 29 minutes to jet from IAD to Florence Regional Airport. Relax and enjoy the trip, because you'll be walking through arrivals in a heartbeat.
How many hours flight from IAD to Florence Regional Airport (FLO)?
The typical flight time from IAD to Florence Regional Airport is an easy 2 hours and 40 minutes. So, grab your bags and hop on a flight. There's nothing more fun than a spontaneous getaway.
What airlines have the most flights from Dulles Intl. Airport to Florence Regional Airport?
Watch the planes take off and land, grab a glazed doughnut, get the blood pumping again .... Airport stopovers don't have to be a bore! If you're traveling from IAD to FLO, you can't fly direct. Plan for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.