Cheap flights from DSM to VPS (Des Moines Intl. to Northwest Florida Regional)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from DSM to VPS starting at $138 One Way, $302 Round Trip

Prices starting at $302 for return flights and $138 for one-way flights to Northwest Florida Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Aug 20 - Tue, Aug 25
DSM
Des Moines
VPS
Fort Walton Beach
$302 Roundtrip, found 1 day ago
$302
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Thu, Aug 20 from Des Moines to Fort Walton Beach, returning Tue, Aug 25, priced at $302 found 1 day ago
Thu, Aug 20 - Tue, Aug 25
DSM
Des Moines
VPS
Fort Walton Beach
$307 Roundtrip, found 1 day ago
$307
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Thu, Aug 20 from Des Moines to Fort Walton Beach, returning Tue, Aug 25, priced at $307 found 1 day ago
Tue, Jun 9 - Tue, Jun 16
DSM
Des Moines
VPS
Fort Walton Beach
$341 Roundtrip, found 6 hours ago
$341
Roundtrip
found 6 hours ago
Select Delta flight, departing Tue, Jun 9 from Des Moines to Fort Walton Beach, returning Tue, Jun 16, priced at $341 found 6 hours ago
Tue, Jun 9 - Tue, Jun 16
DSM
Des Moines
VPS
Fort Walton Beach
$341 Roundtrip, found 6 hours ago
$341
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Tue, Jun 9 from Des Moines to Fort Walton Beach, returning Tue, Jun 16, priced at $341 found 6 hours ago
Thu, Aug 20 - Tue, Aug 25
DSM
Des Moines
VPS
Fort Walton Beach
$346 Roundtrip, found 1 day ago
$346
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Thu, Aug 20 from Des Moines to Fort Walton Beach, returning Tue, Aug 25, priced at $346 found 1 day ago

Hotel Ideas near Northwest Florida Regional

Airport Hotels near Northwest Florida Regional

Holiday Inn Express & Suites Niceville - Eglin Area by IHG

Holiday Inn Express & Suites Niceville - Eglin Area by IHG

2.5 out of 5
410 West John Sims Parkway Niceville FL
$153 nightly
The price is $173 total per night from May 19 to May 20
$173 total
May 19 - May 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Niceville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (937 reviews)
Amazing and we will always choose this hotel when we visit this area again

Reviewed on Apr 19, 2026

Holiday Inn Express & Suites Niceville - Eglin Area by IHG
Holiday Inn Express & Suites Fort Walton Beach Eglin Area by IHG

Holiday Inn Express & Suites Fort Walton Beach Eglin Area by IHG

2.5 out of 5
300 Liberty Lane NW Fort Walton Beach FL
$126 nightly
The price is $142 total per night from Apr 26 to Apr 27
$142 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Walton Beach. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Okaloosa Island Beach ...
9.8/10 Exceptional! (413 reviews)
The staff was VERY friendly. The hotel was clean everywhere I went. The breakfast was yummy and had different choices each day which kept it interesting instead of boring. I can see myself definitely coming back if I come this way.

Reviewed on Apr 19, 2026

Holiday Inn Express & Suites Fort Walton Beach Eglin Area by IHG
The Island Resort at Fort Walton Beach

The Island Resort at Fort Walton Beach

4 out of 5
Miracle Strip Parkway Southeast, 1500 Fort Walton Beach FL
$219 nightly
The price is $246 total per night from Apr 26 to Apr 27
$246 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this beach resort in Fort Walton Beach. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (3,056 reviews)
The outside areas are beautiful pool, courtyard and beach access was amazing. The hot tub was not working and only clean one of the days. The room was out dated but clean. The worst thing is the AC is on a timer. My hot flashes AC on a timer sucked. The staff explained it like it is what it is ...

Reviewed on Apr 21, 2026

The Island Resort at Fort Walton Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Fort Walton Beach

The Island Resort at Fort Walton Beach

The Island Resort at Fort Walton Beach

4 out of 5
Miracle Strip Parkway Southeast, 1500 Fort Walton Beach FL
$219 nightly
The price is $246 total per night from Apr 26 to Apr 27
$246 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this beach resort in Fort Walton Beach. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (3,056 reviews)
The outside areas are beautiful pool, courtyard and beach access was amazing. The hot tub was not working and only clean one of the days. The room was out dated but clean. The worst thing is the AC is on a timer. My hot flashes AC on a timer sucked. The staff explained it like it is what it is ...

Reviewed on Apr 21, 2026

The Island Resort at Fort Walton Beach
Hilton Sandestin Beach Golf Resort & Spa

Hilton Sandestin Beach Golf Resort & Spa

4 out of 5
4000 S Sandestin Blvd Miramar Beach FL
$301 nightly
The price is $337 total per night from Apr 27 to Apr 28
$337 total
Apr 27 - Apr 28
Total with taxes and fees
Book a stay at this beach resort in Miramar Beach. Enjoy 2 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,005 reviews)
The only thing I didn't like was that the room cleaning wasn't completed—they didn't replace the glasses, they didn't clean the shower, and one day they didn't clean at all, leaving neither water nor coffee.

Reviewed on Apr 18, 2026

Hilton Sandestin Beach Golf Resort & Spa
Courtyard by Marriott Sandestin Grand Boulevard

Courtyard by Marriott Sandestin Grand Boulevard

3 out of 5
100 Grand Blvd Miramar Beach FL
$106 nightly
The price is $119 total per night from Apr 27 to Apr 28
$119 total
Apr 27 - Apr 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Miramar Beach. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
9.2/10 Wonderful! (1,627 reviews)
Excellent accommodations, friendly staff and above all very well maintained

Reviewed on Apr 21, 2026

Courtyard by Marriott Sandestin Grand Boulevard
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

DSM to VPS Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
DSM Address & GPS
Address:
5800 Fleur Drive, Suite 201
Des Moines IA, 50321-2854
United States
IATA Code:
DSM
Longitude:
-93.648087
Latitude:
41.532434
Time Zone:
America/Chicago
VPS Address & GPS
Address:
Fort Walton Beach FL,
United States
IATA Code:
VPS
Longitude:
-86.549461
Latitude:
30.495913
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from DSM to Northwest Florida Regional Airport (VPS)?
You'll have to swap planes if you're planning to fly from Des Moines Intl. Airport to Destin–Fort Walton Beach Airport. A range of carriers service this route with only one stopover, including American Airlines, Delta Air Lines and KLM.
What is the shortest flight from Des Moines Intl. Airport (DSM) to Destin–Fort Walton Beach Airport?
Order an in-flight wine or two and get comfy in your seat with an absorbing movie or book. With the trip from Des Moines to Fort Walton Beach taking 4 hours and 9 minutes, you'll have enough time to enjoy the flying experience.
How many hours flight from Des Moines Intl. Airport to Northwest Florida Regional Airport (VPS)?
From DSM to VPS, you'll be in your seat for roughly 4 hours and 18 minutes. Get cozy, order a wine and put on your noise-canceling earphones. It's time to binge-watch some awesome TV shows.
What airlines have the most flights from Des Moines Intl. Airport (DSM) to Northwest Florida Regional Airport (VPS)?
At the moment, no airlines have direct flights from Des Moines Intl. Airport to VPS. Don't panic though! There are numerous single or multi-stop flights available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore