Cheap flights from DSM to VPS (Des Moines Intl. to Northwest Florida Regional)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from DSM to VPS starting at $180 One Way, $353 Round Trip

Prices starting at $353 for return flights and $180 for one-way flights to Northwest Florida Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Sep 23 - Wed, Sep 30
DSM
Des Moines
VPS
Fort Walton Beach
$353 Roundtrip, found 20 hours ago
$353
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Sep 23 from Des Moines to Fort Walton Beach, returning Wed, Sep 30, priced at $353 found 20 hours ago
Wed, Sep 23 - Wed, Sep 30
DSM
Des Moines
VPS
Fort Walton Beach
$353 Roundtrip, found 20 hours ago
$353
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Sep 23 from Des Moines to Fort Walton Beach, returning Wed, Sep 30, priced at $353 found 20 hours ago
Wed, Jul 15 - Wed, Jul 22
DSM
Des Moines
VPS
Fort Walton Beach
$362 Roundtrip, found 20 hours ago
$362
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Jul 15 from Des Moines to Fort Walton Beach, returning Wed, Jul 22, priced at $362 found 20 hours ago
Wed, Jul 15 - Wed, Jul 22
DSM
Des Moines
VPS
Fort Walton Beach
$378 Roundtrip, found 20 hours ago
$378
Roundtrip
found 20 hours ago
Select Southwest Airlines flight, departing Wed, Jul 15 from Des Moines to Fort Walton Beach, returning Wed, Jul 22, priced at $378 found 20 hours ago
Wed, Jul 15 - Wed, Jul 22
DSM
Des Moines
VPS
Fort Walton Beach
$379 Roundtrip, found 20 hours ago
$379
Roundtrip
found 20 hours ago
Select Southwest Airlines flight, departing Wed, Jul 15 from Des Moines to Fort Walton Beach, returning Wed, Jul 22, priced at $379 found 20 hours ago

Hotel Ideas near Northwest Florida Regional

Airport Hotels near Northwest Florida Regional

Holiday Inn Express & Suites Niceville - Eglin Area by IHG

Holiday Inn Express & Suites Niceville - Eglin Area by IHG

2.5 out of 5
410 West John Sims Parkway Niceville FL
$197 nightly
The price is $223 total per night from Jul 1 to Jul 2
$223 total
Jul 1 - Jul 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Niceville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (971 reviews)
"The room was super comfortable and the breakfast was great. We also enjoyed the pool which was clean and refreshing. Marie and Jada at the front desk were incredibly kind and helpful. Even the cleaning staff was great. The location is also good to avoid the crazy traffic at the beach while still ..."

Reviewed on Jun 2, 2026

Holiday Inn Express & Suites Niceville - Eglin Area by IHG
Best Western Niceville - Eglin AFB Hotel

Best Western Niceville - Eglin AFB Hotel

2.5 out of 5
106 Bayshore Dr Niceville FL
$150 nightly
The price is $169 total per night from Jun 7 to Jun 8
$169 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Niceville. Enjoy free breakfast, free parking, and room service. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (747 reviews)
"I am very happy with our choice to stay at the Best Western near Eglin Air Force Base. It was very clean. The staff was extremely friendly and helpful. The pool was a bit small, but the property itself was great. The room was spacious and the price was very reasonable."

Reviewed on Jun 1, 2026

Best Western Niceville - Eglin AFB Hotel
Holiday Inn Express & Suites Fort Walton Beach Eglin Area by IHG

Holiday Inn Express & Suites Fort Walton Beach Eglin Area by IHG

2.5 out of 5
300 Liberty Lane NW Fort Walton Beach FL
$155 nightly
The price is $175 total per night from Jul 1 to Jul 2
$175 total
Jul 1 - Jul 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Walton Beach. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Okaloosa Island Beach ...
9.8/10 Exceptional! (468 reviews)
"The property is clean, comfortable beds, delicious breakfast, very comfortable room. I highly recommend staying here."

Reviewed on May 31, 2026

Holiday Inn Express & Suites Fort Walton Beach Eglin Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Fort Walton Beach

Sandestin Golf and Beach Resort

Sandestin Golf and Beach Resort

4 out of 5
9300 Emerald Coast Pkwy W Miramar Beach FL
$296 nightly
The price is $332 total per night from Jun 7 to Jun 8
$332 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this beach aparthotel in Miramar Beach. Enjoy free WiFi, free parking, and 4 outdoor pools. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (3,909 reviews)
"I will be returning again and again. I didn’t want to leave. The resort was amazing and blew my expectations out of the water. It’s great for families, couples, solo trips, or whatever you should decide. It’s spacious and truly felt like home away from home. The amenities and dining facilities are ..."

Reviewed on Jun 1, 2026

Sandestin Golf and Beach Resort
The Island Resort at Fort Walton Beach

The Island Resort at Fort Walton Beach

4 out of 5
Miracle Strip Parkway Southeast, 1500 Fort Walton Beach FL
$293 nightly
The price is $331 total per night from Jun 7 to Jun 8
$331 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this beach resort in Fort Walton Beach. Enjoy free WiFi, 2 outdoor pools, and 3 restaurants. Our guests praise the breakfast and the pool in our ...
8.2/10 Very Good! (3,198 reviews)
"This was my second time staying there and it great again. The staff, everyone from the person who checks you in at the front to the restaurant staff to the people who clean the rooms, were always nice. And no matter how much sand we managed to bring back to our room, it was spotless every time they ..."

Reviewed on Jun 3, 2026

The Island Resort at Fort Walton Beach
Courtyard by Marriott Sandestin at Grand Boulevard

Courtyard by Marriott Sandestin at Grand Boulevard

3 out of 5
100 Grand Blvd Miramar Beach FL
$152 nightly
The price is $171 total per night from Jun 7 to Jun 8
$171 total
Jun 7 - Jun 8
Total with taxes and fees
Book a stay at this business-friendly hotel in Miramar Beach. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
9.2/10 Wonderful! (1,691 reviews)
"Nice and clean hotel. The only bad thing was the elevator took too long."

Reviewed on Jun 3, 2026

Courtyard by Marriott Sandestin at Grand Boulevard
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

DSM to VPS Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
DSM Address & GPS
Address:
5800 Fleur Drive, Suite 201
Des Moines IA, 50321-2854
United States
IATA Code:
DSM
Longitude:
-93.648087
Latitude:
41.532434
Time Zone:
America/Chicago
VPS Address & GPS
Address:
Fort Walton Beach FL,
United States
IATA Code:
VPS
Longitude:
-86.549461
Latitude:
30.495913
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from DSM to Northwest Florida Regional Airport (VPS)?
You'll have to swap planes if you're planning to fly from Des Moines Intl. Airport to Destin–Fort Walton Beach Airport. A range of carriers service this route with only one stopover, including American Airlines, Delta Air Lines and KLM.
What is the shortest flight from Des Moines Intl. Airport (DSM) to Destin–Fort Walton Beach Airport?
Order an in-flight wine or two and get comfy in your seat with an absorbing movie or book. With the trip from Des Moines to Fort Walton Beach taking 4 hours and 9 minutes, you'll have enough time to enjoy the flying experience.
How many hours flight from Des Moines Intl. Airport to Northwest Florida Regional Airport (VPS)?
From DSM to VPS, you'll be in your seat for roughly 4 hours and 18 minutes. Get cozy, order a wine and put on your noise-canceling earphones. It's time to binge-watch some awesome TV shows.
What airlines have the most flights from Des Moines Intl. Airport (DSM) to Northwest Florida Regional Airport (VPS)?
At the moment, no airlines have direct flights from Des Moines Intl. Airport to VPS. Don't panic though! There are numerous single or multi-stop flights available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore