Cheap flights from DSM to VPS (Des Moines Intl. to Northwest Florida Regional)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from DSM to VPS starting at $145 One Way, $326 Round Trip

Prices starting at $326 for return flights and $145 for one-way flights to Northwest Florida Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Mar 31 - Wed, Apr 1
DSM
Des Moines
VPS
Fort Walton Beach
$326 Roundtrip, found 3 days ago
$326
Roundtrip
found 3 days ago
Select Delta flight, departing Tue, Mar 31 from Des Moines to Fort Walton Beach, returning Wed, Apr 1, priced at $326 found 3 days ago
Sat, Apr 25 - Wed, Apr 29
DSM
Des Moines
VPS
Fort Walton Beach
$331 Roundtrip, found 12 hours ago
$331
Roundtrip
found 12 hours ago
Select Delta flight, departing Sat, Apr 25 from Des Moines to Fort Walton Beach, returning Wed, Apr 29, priced at $331 found 12 hours ago
Sat, Apr 25 - Wed, Apr 29
DSM
Des Moines
VPS
Fort Walton Beach
$333 Roundtrip, found 12 hours ago
$333
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Sat, Apr 25 from Des Moines to Fort Walton Beach, returning Wed, Apr 29, priced at $333 found 12 hours ago
Tue, May 5 - Tue, May 19
DSM
Des Moines
VPS
Fort Walton Beach
$335 Roundtrip, found 1 day ago
$335
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, May 5 from Des Moines to Fort Walton Beach, returning Tue, May 19, priced at $335 found 1 day ago
Tue, Apr 14 - Sat, Apr 18
DSM
Des Moines
VPS
Fort Walton Beach
$336 Roundtrip, found 18 hours ago
$336
Roundtrip
found 18 hours ago
Select American Airlines flight, departing Tue, Apr 14 from Des Moines to Fort Walton Beach, returning Sat, Apr 18, priced at $336 found 18 hours ago

Hotel Ideas near Northwest Florida Regional

Airport Hotels near Northwest Florida Regional

Holiday Inn Express & Suites Fort Walton Beach Eglin Area by IHG

Holiday Inn Express & Suites Fort Walton Beach Eglin Area by IHG

2.5 out of 5
300 Liberty Lane NW Fort Walton Beach FL
$126 nightly
The price is $142 total per night from Mar 15 to Mar 16
$142 total
Mar 15 - Mar 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Walton Beach. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Okaloosa Island Beach ...
9.8/10 Exceptional! (364 reviews)
Marvelous at the front desk was so nice and helpful! The entire place smelled amazing, and the rooms were spotless.

Reviewed on Mar 1, 2026

Holiday Inn Express & Suites Fort Walton Beach Eglin Area by IHG
TownePlace Suites by Marriott Fort Walton Beach-Eglin AFB

TownePlace Suites by Marriott Fort Walton Beach-Eglin AFB

3 out of 5
843 Eglin Parkway Fort Walton Beach FL
$152 nightly
The price is $172 total per night from Mar 29 to Mar 30
$172 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Walton Beach. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Boardwalk on Okaloosa ...
8.8/10 Excellent! (500 reviews)
The room was in good condition unfortunately it was next to the door to the parking lot, and people don't seen to be aware that there are other guest sleeping next to the door. The door will slam all night, there is no way to sleep because of the noise it makes plus the walls literally vibrate every ...

Reviewed on Feb 17, 2026

TownePlace Suites by Marriott Fort Walton Beach-Eglin AFB
The Island Resort at Fort Walton Beach

The Island Resort at Fort Walton Beach

4 out of 5
Miracle Strip Parkway Southeast, 1500 Fort Walton Beach FL
$177 nightly
The price is $200 total per night from Mar 11 to Mar 12
$200 total
Mar 11 - Mar 12
Total with taxes and fees
Book a stay at this beach resort in Fort Walton Beach. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the breakfast and the pool in our ...
8.4/10 Very Good! (2,984 reviews)
Room was not the cleanest (spray from something in the ceiling) the grotto was closed along with the beach bar and we got no discounts on our stay even though that info was not posted or give. To use prior to booking. Also they charge for parking nothing in the booking about this. It’s an okay place ...

Reviewed on Mar 4, 2026

The Island Resort at Fort Walton Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Fort Walton Beach

The Island Resort at Fort Walton Beach

The Island Resort at Fort Walton Beach

4 out of 5
Miracle Strip Parkway Southeast, 1500 Fort Walton Beach FL
$177 nightly
The price is $200 total per night from Mar 11 to Mar 12
$200 total
Mar 11 - Mar 12
Total with taxes and fees
Book a stay at this beach resort in Fort Walton Beach. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the breakfast and the pool in our ...
8.4/10 Very Good! (2,984 reviews)
Room was not the cleanest (spray from something in the ceiling) the grotto was closed along with the beach bar and we got no discounts on our stay even though that info was not posted or give. To use prior to booking. Also they charge for parking nothing in the booking about this. It’s an okay place ...

Reviewed on Mar 4, 2026

The Island Resort at Fort Walton Beach
Wyndham Garden Fort Walton Beach Destin

Wyndham Garden Fort Walton Beach Destin

3 out of 5
573 Santa Rosa Blvd Fort Walton Beach FL
$178 nightly
The price is $201 total per night from Mar 12 to Mar 13
$201 total
Mar 12 - Mar 13
Total with taxes and fees
Book a stay at this beach hotel in Fort Walton Beach. Enjoy free WiFi, 2 outdoor pools, and a beach locale. Our guests praise the pool and the helpful staff ...
8/10 Very Good! (2,176 reviews)
Ocean view was amazing!

Reviewed on Mar 4, 2026

Wyndham Garden Fort Walton Beach Destin
Hilton Garden Inn Destin Miramar Beach

Hilton Garden Inn Destin Miramar Beach

3 out of 5
220 Scenic Gulf Drive Miramar Beach FL
$134 nightly
The price is $150 total per night from Mar 22 to Mar 23
$150 total
Mar 22 - Mar 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Miramar Beach. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff ...
8.8/10 Excellent! (1,143 reviews)
No view description deceiving thought there was ocean view very disappointed

Reviewed on Mar 5, 2026

Hilton Garden Inn Destin Miramar Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

DSM to VPS Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
DSM Address & GPS
Address:
5800 Fleur Drive, Suite 201
Des Moines IA, 50321-2854
United States
IATA Code:
DSM
Longitude:
-93.648087
Latitude:
41.532434
Time Zone:
America/Chicago
VPS Address & GPS
Address:
Fort Walton Beach FL,
United States
IATA Code:
VPS
Longitude:
-86.549461
Latitude:
30.495913
Time Zone:
America/Chicago

Frequently asked questions

Are there non-stop flights from DSM to Northwest Florida Regional Airport (VPS)?
You'll have to swap planes if you're planning to fly from Des Moines Intl. Airport to Destin–Fort Walton Beach Airport. A range of carriers service this route with only one stopover, including American Airlines, Delta Air Lines and KLM.
What is the shortest flight from Des Moines Intl. Airport (DSM) to Destin–Fort Walton Beach Airport?
Order an in-flight wine or two and get comfy in your seat with an absorbing movie or book. With the trip from Des Moines to Fort Walton Beach taking 4 hours and 9 minutes, you'll have enough time to enjoy the flying experience.
How many hours flight from Des Moines Intl. Airport to Northwest Florida Regional Airport (VPS)?
From DSM to VPS, you'll be in your seat for roughly 4 hours and 18 minutes. Get cozy, order a wine and put on your noise-canceling earphones. It's time to binge-watch some awesome TV shows.
What airlines have the most flights from Des Moines Intl. Airport (DSM) to Northwest Florida Regional Airport (VPS)?
At the moment, no airlines have direct flights from Des Moines Intl. Airport to VPS. Don't panic though! There are numerous single or multi-stop flights available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore