Cheap flights from CAK to FLO (Akron-Canton to Florence Regional)

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Hotel Ideas near Florence Regional

Airport Hotels near Florence Regional

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
$100 nightly
The price is $112 total per night from Feb 2 to Feb 3
$112 total
Feb 2 - Feb 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,000 reviews)
No dinner options

Reviewed on Jan 13, 2026

Hyatt Place Florence Downtown
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3 out of 5
126 W Evans St Florence SC
$130 nightly
The price is $146 total per night from Jan 25 to Jan 26
$146 total
Jan 25 - Jan 26
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (613 reviews)
Didn't stay long enough to try any of the amenities that they offer.

Reviewed on Jan 11, 2026

Hotel Florence, Tapestry Collection by Hilton
Charming and Cozy 4BR 2BA House with Parking, Minutes from I-95 and Buc-ees

Charming and Cozy 4BR 2BA House with Parking, Minutes from I-95 and Buc-ees

Florence SC
Stay at this vacation home in Florence. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Old Greenwood Athletic Park and Greenwood Baseball ...
9.6/10 Exceptional! (6 reviews)
The house was nice and had everything we needed. Everything was clean.

Reviewed on Sep 1, 2025

Get rates
Charming and Cozy 4BR 2BA House with Parking, Minutes from I-95 and Buc-ees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Florence

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
$70 nightly
The price is $79 total per night from Jan 17 to Jan 18
$79 total
Jan 17 - Jan 18
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,530 reviews)
Great price, beds were comfortable though pillows were a little weak. Clean and quiet. Slightly substandard continental breakfast that we just avoided but still a great value stay.

Reviewed on Jan 13, 2026

Howard Johnson by Wyndham Florence
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
$85 nightly
The price is $95 total per night from Jan 18 to Jan 19
$95 total
Jan 18 - Jan 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (2,235 reviews)
Stay was nice had no issues. Very quiet. Great breakfast choices

Reviewed on Jan 13, 2026

Park Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
$93 nightly
The price is $104 total per night from Feb 1 to Feb 2
$104 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,187 reviews)
Nice staff, clean, , convenient location

Reviewed on Jan 13, 2026

Comfort Inn & Suites Florence Center Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Florence Hotels

Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2 out of 5
2690 David H McLeod Boulevard Florence SC
$56 nightly
The price is $63 total per night from Jan 19 to Jan 20
$63 total
Jan 19 - Jan 20
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.6/10 (1,000 reviews)
Room was good. No microwave tho. Staff was very courteous and helpful

Reviewed on Jan 9, 2026

Red Roof Inn Florence - Civic Center
Budget Inn Timmonsville

Budget Inn Timmonsville

2 out of 5
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from Jan 18 to Jan 19
$68 total
Jan 18 - Jan 19
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (324 reviews)
Clean room, great for price, stayed with spouse, 2 children and two pets. You can hear cars pulling in and out of this location. There was a homeless guy asking for money but you can encounter that anywhere. No bugs, no concerns. :)

Reviewed on Dec 29, 2025

Budget Inn Timmonsville
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$59 nightly
The price is $66 total per night from Jan 22 to Jan 23
$66 total
Jan 22 - Jan 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,000 reviews)
Receptionist was very professional and polite. And took her time to answer every question.

Reviewed on Jan 1, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Florence

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

3 out of 5
900 Woody Jones Blvd Florence SC
$106 nightly
The price is $119 total per night from Feb 8 to Feb 9
$119 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,005 reviews)
The service at this location is always great, I stay at this location every time that I’m in town.

Reviewed on Jan 12, 2026

Home2 Suites by Hilton Florence, SC
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
$101 nightly
The price is $113 total per night from Jan 26 to Jan 27
$113 total
Jan 26 - Jan 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (40 reviews)
Staff was great, the room was very clean and new

Reviewed on Jan 15, 2026

Spark by Hilton Florence North I-95, SC
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$59 nightly
The price is $66 total per night from Jan 22 to Jan 23
$66 total
Jan 22 - Jan 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,000 reviews)
Receptionist was very professional and polite. And took her time to answer every question.

Reviewed on Jan 1, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

CAK to FLO Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

What is the shortest flight from Akron-Canton Airport (CAK) to Florence Regional Airport?
If conditions are good and all goes as scheduled, you could be stepping off the plane at Florence Regional Airport (FLO) from Akron-Canton Airport in only 2 hours and 45 minutes. With such a brief flight time, contemplate taking just hand luggage.
How many hours flight from Akron-Canton Airport to FLO?
The typical flight time from CAK to FLO is a short and sweet 2 hours and 53 minutes. So, pack your bags and jump on a flight. There's nothing more exhilarating than an impromptu vacation.
What airlines have the most flights from CAK to Florence Regional Airport?
At the moment, no airlines offer direct flights between CAK and Florence Regional Airport (FLO). But don't panic! There are several single or multi-stop flights available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.