$77 Cheap flight deals from Fort Collins (DEN) to Knoxville (TYS)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Fort Collins to Knoxville

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Jun 22 - Sun, Jun 29
DEN
Denver Intl.
TYS
McGhee Tyson
$211 Roundtrip, found 2 days ago
$211
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sun, Jun 22 from Denver Intl. to McGhee Tyson, returning Sun, Jun 29, priced at $211 found 2 days ago

Airfares from $77 One Way, $131 Round Trip from Fort Collins to Knoxville

Prices starting at $131 for return flights and $77 for one-way flights to Knoxville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Sep 4 - Sun, Sep 7
DEN
Denver
TYS
Knoxville
$131 Roundtrip, just found
$131
Roundtrip
just found
Select Frontier Airlines flight, departing Thu, Sep 4 from Denver to Knoxville, returning Sun, Sep 7, priced at $131 just found
Thu, Aug 14 - Sun, Aug 17
DEN
Denver
TYS
Knoxville
$133 Roundtrip, just found
$133
Roundtrip
just found
Select Frontier Airlines flight, departing Thu, Aug 14 from Denver to Knoxville, returning Sun, Aug 17, priced at $133 just found
Thu, Oct 2 - Sun, Oct 5
DEN
Denver
TYS
Knoxville
$160 Roundtrip, found 6 hours ago
$160
Roundtrip
found 6 hours ago
Select Frontier Airlines flight, departing Thu, Oct 2 from Denver to Knoxville, returning Sun, Oct 5, priced at $160 found 6 hours ago
Thu, Jul 31 - Sun, Aug 3
DEN
Denver
TYS
Knoxville
$163 Roundtrip, found 4 days ago
$163
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Jul 31 from Denver to Knoxville, returning Sun, Aug 3, priced at $163 found 4 days ago
Thu, Sep 4 - Sun, Sep 7
DEN
Denver
TYS
Knoxville
$169 Roundtrip, just found
$169
Roundtrip
just found
Select Frontier Airlines flight, departing Thu, Sep 4 from Denver to Knoxville, returning Sun, Sep 7, priced at $169 just found

Knoxville economy flight packages

Price found within the past 48 hours. Click for updated prices.
Tennessee Mountain Lodge Riverside by OYO
2.0-star property

Tennessee Mountain Lodge Riverside by OYO

7.4/10 Good! (1,003 reviews)

Jul 25 - Jul 27

2 night stay

Denver (DEN) to Knoxville (TYS)

United • Coach

Knoxville (TYS) to Denver (DEN)

Frontier Airlines • Coach
per person
found 1 day ago
Easily accessed my reservation and thebstaff were extremely helpful and nice

Reviewed on Apr 7, 2025

Baymont by Wyndham Gatlinburg On The River
2.5-star property

Baymont by Wyndham Gatlinburg On The River

8.4/10 Very Good! (1,419 reviews)

Jul 25 - Jul 27

2 night stay

Denver (DEN) to Knoxville (TYS)

United • Coach

Knoxville (TYS) to Denver (DEN)

Frontier Airlines • Coach
per person
found 1 day ago
Loved the balconies on the river, super clean and can't beat the price.

Reviewed on Nov 12, 2024

OYO Hotel Knoxville TN Cedar Bluff I-40
2.5-star property

OYO Hotel Knoxville TN Cedar Bluff I-40

5/10 (807 reviews)

Jul 25 - Jul 27

2 night stay

Denver (DEN) to Knoxville (TYS)

United • Coach

Knoxville (TYS) to Denver (DEN)

Frontier Airlines • Coach
per person
found 1 day ago
Dingy, but clean bedding and carpet. Old hotel, needs updating. Was alright for a 1 night, emergency stay.

Reviewed on May 18, 2025

Don't see what you're looking for?
See all available trips from Fort Collins to Knoxville
View all trips

More About Flying To Knoxville from Fort Collins

Route Information for Flights from Fort Collins to Knoxville

Origin Airport IATA Code
DEN
Destination Airport IATA Code
TYS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Fort Collins to Knoxville

Trip-Planning Made Easy

Your search engine may give you thousands of pages of results when you search for cheap flights from Fort Collins to Knoxville, but you can save yourself a lot of hassle and money by going straight to Orbitz.com. Not only do we offer great deals on Fort Collins to Knoxville flights, but we make it easy to book hotels, car rentals, cruises, or a complete vacation package of your dreams.

Discount Fort Collins to Knoxville Flights

Orbitz’s low price guarantee means you get the best fares around. Find the lowest prices for international and domestic tickets and for flights from Fort Collins to Knoxville when you use Orbitz. It’s easy to add activities to your booking, so you can take advantage of all that Knoxville has to offer.

Easily Book, Change, Cancel Flights From Fort Collins to Knoxville

Orbitz now offers free mobile device apps, so even the busiest multi-taskers can plan their vacations while away from their desktop computer. Plus, instant alerts to your email or mobile phone help you stay on top of any delays or travel updates, so you avoid unpleasant surprises before boarding your Fort Collins to Knoxville flights. Our Customer Service representatives are ready to assist you if you need to change your air travel plans.

Take Advantage of Frequent Flyer Options Through Orbitz

With Orbitz, you do not have to choose between a low fare and earning frequent flyer miles. Simply provide your frequent flyer information when you book your Fort Collins to Knoxville flights.

Frequently asked questions

Are there non-stop flights from Fort Collins to Knoxville?
Yes, if you're cruising from Denver, CO (DEN-Denver Intl.) to McGhee Tyson Airport (TYS), you'll only have one flight number to keep track of. There are 3 airlines offering direct services to select from. Here are a few of the best:
  • United Airlines
  • Frontier Airlines
  • Allegiant Air

What is the shortest flight from Fort Collins to Knoxville?
The shortest flight time from DIA airport to TYS is 3 hours and 37 minutes, which gives you loads of time to enjoy a drink or lose yourself in a gripping novel.
What airlines fly from Fort Collins to Knoxville most frequently?
Consider booking a flight with United Airlines (UA), which frequently services this route. This airline offers 60 flights every month between DEN and Knoxville, TN (TYS-McGhee Tyson). Frontier Airlines (F9) will also take you to your destination in style and comfort. Offering 17 flights per month between Fort Collins and Knoxville, it's another quality airline to look into.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.