$234 Cheap flight deals from Des Moines (DSM) to Quad Cities (MLI)

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This Weekend's Flight Deals from Des Moines to Quad Cities

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Aug 22 - Sun, Aug 23
DSM
Des Moines Intl.
MLI
Quad City Intl.
$363 Roundtrip, found 5 hours ago
$363
Roundtrip
found 5 hours ago
Select United flight, departing Sat, Aug 22 from Des Moines Intl. to Quad City Intl., returning Sun, Aug 23, priced at $363 found 5 hours ago

Airfares from $234 One Way, $363 Round Trip from Des Moines to Quad Cities

Prices starting at $363 for return flights and $234 for one-way flights to Quad Cities were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Aug 22 - Sun, Aug 23
DSM
Des Moines
MLI
Moline
$363 Roundtrip, found 5 hours ago
$363
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, Aug 22 from Des Moines to Moline, returning Sun, Aug 23, priced at $363 found 5 hours ago
Sat, Aug 22 - Sun, Aug 23
DSM
Des Moines
MLI
Moline
$363 Roundtrip, found 5 hours ago
$363
Roundtrip
found 5 hours ago
Select United flight, departing Sat, Aug 22 from Des Moines to Moline, returning Sun, Aug 23, priced at $363 found 5 hours ago
Sat, Aug 22 - Sun, Aug 23
DSM
Des Moines
MLI
Moline
$434 Roundtrip, found 5 hours ago
$434
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, Aug 22 from Des Moines to Moline, returning Sun, Aug 23, priced at $434 found 5 hours ago
Sat, Aug 22 - Sun, Aug 23
DSM
Des Moines
MLI
Moline
$445 Roundtrip, found 5 hours ago
$445
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, Aug 22 from Des Moines to Moline, returning Sun, Aug 23, priced at $445 found 5 hours ago
Sat, Aug 22 - Sun, Aug 23
DSM
Des Moines
MLI
Moline
$491 Roundtrip, found 5 hours ago
$491
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, Aug 22 from Des Moines to Moline, returning Sun, Aug 23, priced at $491 found 5 hours ago

More About Flying To Quad Cities from Des Moines

Route Information for Flights from Des Moines to Quad Cities

Origin Airport IATA Code
DSM
Destination Airport IATA Code
MLI
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Des Moines to Quad Cities

It has never been easier to find cheap Des Moines to Quad Cities flights. Orbitz has some of the best deals around to save you more money on your flight, hotel, and vacation package for the trip you have been waiting for.

Plan Your Des Moines to Quad Cities Flights on the Go

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Get the Best Deals on Des Moines to Quad Cities Flights

Finding great deals on flights from Des Moines to Quad Cities is a snap with Orbitz. With our guaranteed low prices, you don’t have to worry if you are getting the best prices on air tickets, hotels, and cruises. And with all that money you saved, you can enjoy your Quad Cities vacation even more.

Pile Up Miles With Discount Air Tickets

Not only can you find great bargains on Des Moines to Quad Cities flights, but you can rack up frequent flyer miles on the flights too. Enter your frequent flyer number on qualified flights when booking for Orbitz to see the miles pile up in your account.

Flight Alerts Keep You Informed

Stay on top of the latest updates for flights from Des Moines to Quad Cities. We send you free email and mobile alerts to keep you informed about delays to Des Moines to Quad Cities flights.

Frequently asked questions

What is the shortest flight from Des Moines to Quad Cities?
If conditions are good and all goes as scheduled, you could be disembarking at Quad City Intl. Airport (MLI) from Des Moines, IA (DSM-Des Moines Intl.) in only 2 hours and 17 minutes. With such a speedy flight time, think about taking carry-on luggage only.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.