
$129 Cheap flight deals from Myrtle Beach (MYR) to Niagara Falls (BUF)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Airfares from $129 One Way, $247 Round Trip from Myrtle Beach to Niagara Falls
Prices starting at $247 for return flights and $129 for one-way flights to Niagara Falls were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Niagara Falls economy flight packages

Niagara Crossing Hotel & Spa
Dec 10 - Dec 14
Myrtle Beach (MYR) to Buffalo (BUF)
Buffalo (BUF) to Myrtle Beach (MYR)
Reviewed on Oct 7, 2025

Seneca Niagara Resort & Casino
Dec 10 - Dec 14
Myrtle Beach (MYR) to Buffalo (BUF)
Buffalo (BUF) to Myrtle Beach (MYR)
Reviewed on Oct 11, 2025

Crowne Plaza Niagara Falls NY Riverside by IHG
Dec 10 - Dec 14
Myrtle Beach (MYR) to Buffalo (BUF)
Buffalo (BUF) to Myrtle Beach (MYR)
Reviewed on Jun 23, 2024
More About Flying To Niagara Falls from Myrtle Beach
Route Information for Flights from Myrtle Beach to Niagara Falls
| Origin Airport IATA Code | MYR | 
|---|---|
| Destination Airport IATA Code | BUF | 
| Distance | |
| Direct Flight Airlines | |
| Earliest Flight Arrival | |
| Latest Flight Arrival | 
Myrtle Beach to Niagara Falls
Those who want guaranteed low prices for Myrtle Beach to Niagara Falls flights only need to visit Orbitz. We take advantage of the latest mobile technologies to make sure you get the best bargain on your trip and that everything goes smoothly and according to your plans.
Take Advantage of Orbitz’s Amazing Customer Service on Myrtle Beach to Niagara Falls Flights
We will help you from booking to boarding on flights from Myrtle Beach to Niagara Falls. Whether you have questions about baggage limits, seat assignments or anything else, we will be there to answer them for you.
Get Great Recommendations For Travel Ideas On Orbitz.com
We do not only get the best bargains on flights from Myrtle Beach to Niagara Falls, but we can tell you what to do once you get there. Whether it is a music festival, hotel recommendation or list of local attractions, Orbitz can help make your travel plan more exciting.
Combine Car Rental With Your Discount Flight For Even More Savings
Not only can we get bargain deals on flights from Myrtle Beach to Niagara Falls but we can book your transport as well. By combining car rental with Myrtle Beach to Niagara Falls flights, you can be sure to save money and start moving as soon as you hit the ground.
Use Orbitz On The Go To Stay Informed Using Your Smartphone
This convenient app works with most smartphones and allows you to see the status of flights from Myrtle Beach to Niagara Falls. You don’t have to worry, if something goes wrong, we’ll let you know.
Frequently asked questions
- Flights to Niagara Falls
- Flights from Myrtle Beach
- Myrtle Beach Airports
- Niagara Falls Airports
- Airlines Operating
- Flights To
Flights to Niagara Falls
- New York to Niagara Falls
- Chicago to Niagara Falls
- Atlanta to Niagara Falls
- Newark to Niagara Falls
- Washington to Niagara Falls
- Orlando to Niagara Falls
- Detroit to Niagara Falls
- San Francisco to Niagara Falls
- Baltimore to Niagara Falls
- Pittsburgh to Niagara Falls
- Toronto to Niagara Falls
- Honolulu to Niagara Falls
- Oakland to Niagara Falls
- Rockford to Niagara Falls
- Boston to Niagara Falls
Flights from Myrtle Beach
- Myrtle Beach to Orlando
- Myrtle Beach to New York
- Myrtle Beach to Dallas
- Myrtle Beach to Hartford
- Myrtle Beach to Houston
- Myrtle Beach to Washington
- Myrtle Beach to Columbus
- Myrtle Beach to Chicago
- Myrtle Beach to New Orleans
- Myrtle Beach to Atlantic City
- Myrtle Beach to Detroit
- Myrtle Beach to Toronto
- Myrtle Beach to Seattle
- Myrtle Beach to Los Angeles
- Myrtle Beach to Manchester
- Myrtle Beach to Kansas City
- Myrtle Beach to London
- Myrtle Beach to Oklahoma City
- Myrtle Beach to Rome
- Myrtle Beach to Montreal
Myrtle Beach Airports
Niagara Falls Airports
More Destinations
- Flights from Anchorage to Grand Island
- Flights from Boston to Grand Island
- Flights from Chicago to Grand Island
- Flights from Kansas City to Grand Island
- Flights from Las Vegas to Grand Island
- Flights from Miami to Grand Island
- Flights from Minneapolis - St. Paul to Grand Island
- Flights from Nashville to Grand Island
- Flights from New York to Grand Island
- Flights from Portland to Grand Island
- Flights from Raleigh to Grand Island
- Flights from San Antonio to Grand Island
- Flights from Lynchburg to Grand Island
- Flights from Billings to Grand Island
- Flights from Burlington to Grand Island
- Flights from Panama City to Grand Island
- Flights from Bentonville - Fayetteville to Grand Island
- Flights from Madison to Grand Island
- Flights from Little Rock to Grand Island
- Flights from Springfield to Grand Island
- Flights from Knoxville to Grand Island
- Flights from Islip to Buffalo
- Flights from Austin to Buffalo
- Flights from Baltimore to Buffalo
- Flights from Cincinnati to Buffalo
- Flights from Cleveland to Buffalo
- Flights from Columbus to Buffalo
- Flights from Denver to Buffalo
- Flights from Detroit to Buffalo
- Flights from Houston to Buffalo
- Flights from Indianapolis to Buffalo
- Flights from Kansas City to Buffalo
- Flights from Las Vegas to Buffalo
- Flights from Miami to Buffalo
- Flights from Minneapolis - St. Paul to Buffalo
- Flights from Montreal to Buffalo
- Flights from Nashville to Buffalo
- Flights from New Orleans to Buffalo
- Flights from New York to Buffalo
- Flights from Philadelphia to Buffalo
- Flights from Phoenix to Buffalo
- Flights from Portland to Buffalo
- Flights from Raleigh to Buffalo
- Flights from Salt Lake City to Buffalo
- Flights from San Antonio to Buffalo
- Flights from San Francisco to Buffalo
- Flights from Seattle to Buffalo
- Flights from St. Louis to Buffalo
- Flights from Toronto to Buffalo
- Flights from Washington to Buffalo
- Flights from Charleston to Buffalo
- Flights from Hartford to Buffalo
- Flights from Providence to Buffalo
- Flights from Myrtle Beach to Buffalo
- Flights from Pittsburgh to Buffalo
- Flights from Fort Lauderdale to Buffalo
- Flights from Richmond to Buffalo
- Flights from Manchester to Buffalo
- Flights from Sarasota to Buffalo
- Flights from Fort Myers to Buffalo
- Flights from Jacksonville to Buffalo
- Flights from White Plains to Buffalo
- Flights from Albany to Buffalo
- Flights from Boston (BOS) to Niagara Falls (IAG)
- Flights from Baltimore (BWI) to Niagara Falls (IAG)
- Flights from Newark Liberty Intl. Airport (EWR) to Niagara Falls (IAG)
- Flights from Washington (IAD) to Niagara Falls (IAG)
- Flights from New York (JFK) to Niagara Falls (IAG)
- Flights from Los Angeles (LAX) to Niagara Falls (IAG)
- Flights from Orlando (MCO) to Niagara Falls (IAG)
- Flights from Philadelphia (PHL) to Niagara Falls (IAG)
- Flights from San Francisco (SFO) to Niagara Falls (IAG)
- Flights from Florence to Amherst
- Flights from Atlanta to Amherst
- Flights from Baltimore to Amherst
- Flights from Houston to Amherst
- Flights from Los Angeles to Amherst
- Flights from Miami to Amherst
- Flights from Nashville to Amherst
- Flights from Orlando to Amherst
- Flights from Portland to Amherst
- Flights from Cabo San Lucas to Amherst
- Flights from Sacramento to Amherst
- Flights from Lynchburg to Amherst
- Flights from Des Moines to Amherst
- Flights from Fort Lauderdale to Amherst
- Flights from Richmond to Amherst
- Flights from Nassau to Amherst
- Flights from Bentonville - Fayetteville to Amherst
- Flights from Albuquerque to Amherst
- Flights from Reno to Amherst
- Flights from Oklahoma City to Amherst
- Flights from Louisville to Amherst
- Flights from San José to Amherst
- Flights from Asheville to Amherst
- Flights from Bangor to Amherst
- Flights from Lubbock to Amherst
- Flights from Bozeman to Amherst
- Flights from Chattanooga to Amherst
- Flights from Columbia to Amherst
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

