$72 Cheap flight deals from Minneapolis - St. Paul (MSP) to Southern Illinois (STL)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
This Weekend's Flight Deals from Minneapolis - St. Paul to Southern Illinois
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $72 One Way, $143 Round Trip from Minneapolis - St. Paul to Southern Illinois
Prices starting at $143 for return flights and $72 for one-way flights to Southern Illinois were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Southern Illinois economy flight packages
The Wildwood Hotel
Nov 20 - Nov 22
Minneapolis (MSP) to St. Louis (STL)
St. Louis (STL) to Minneapolis (MSP)
Reviewed on Oct 20, 2026
Ameristar Casino Resort and Spa
Nov 20 - Nov 22
Minneapolis (MSP) to St. Louis (STL)
St. Louis (STL) to Minneapolis (MSP)
Reviewed on Oct 21, 2026
More About Flying To Southern Illinois from Minneapolis - St. Paul
Route Information for Flights from Minneapolis - St. Paul to Southern Illinois
Origin Airport IATA Code | MSP |
|---|---|
Destination Airport IATA Code | STL |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Minneapolis - St. Paul to Southern Illinois
The best fares for Minneapolis - St. Paul to Southern Illinois flights are always found on Orbitz. With superior discounts and the latest innovations in mobile access, your ideal trip starts with Orbitz.
The Easy Way to Plan Travel Cheaply
We provide access to many low-cost vacation packages and travelers can mix and match airlines when scheduling their flights for the best prices and flight times. Finding cheap tickets on flights from Minneapolis - St. Paul to Southern Illinois is easy when you make Orbitz your #1 travel planner.
Book Minneapolis - St. Paul to Southern Illinois Flights With Mobile Apps
Our iPhone and Android mobile apps can be used to compare and book flights from Minneapolis - St. Paul to Southern Illinois. These apps are perfect for checking the status of flights, gate and baggage claims details, car rental rates, and for receiving alerts on special savings that are exclusive to mobile users. Mobile app users can even score great rates when booking hotel rooms. You can compare hotels, virtually view photo galleries, and check out user reviews using the app, as well as find out which ones are closest to you.
Orbitz also offers free travel updates that are sent to your email or mobile phone that notifies you of booking changes, disruptions in service, or delayed flights.
Increase Your Rewards While Enjoying Super Low Rates
Boost your points or miles for your frequent flyer program on certain Minneapolis - St. Paul to Southern Illinois flights. Simply provide your frequent flyer information when booking flights from Minneapolis - St. Paul to Southern Illinois with Orbitz and get both a low fare and travel rewards. You can enter this information in your Orbitz account profile for easy remembering in future bookings.
- Flights from Minneapolis - St. Paul
- Minneapolis - St. Paul Airports
- Southern Illinois Airports
- Airlines Operating
- Book on Expedia
Flights from Minneapolis - St. Paul
- Minneapolis - St. Paul to Chicago
- Minneapolis - St. Paul to Phoenix
- Minneapolis - St. Paul to Orlando
- Minneapolis - St. Paul to Seattle
- Minneapolis - St. Paul to Houston
- Minneapolis - St. Paul to Los Angeles
- Minneapolis - St. Paul to New York
- Minneapolis - St. Paul to Dallas
- Minneapolis - St. Paul to Anchorage
- Minneapolis - St. Paul to London
- Minneapolis - St. Paul to Sacramento
- Minneapolis - St. Paul to New Orleans
- Minneapolis - St. Paul to Toronto
- Minneapolis - St. Paul to San Francisco
- Minneapolis - St. Paul to Detroit
- Minneapolis - St. Paul to Billings
- Minneapolis - St. Paul to Kansas City
- Minneapolis - St. Paul to Paris
- Minneapolis - St. Paul to Washington
- Minneapolis - St. Paul to Montreal
More Destinations
- Flights from Anshan (AOG) to Marion (MWA)
- Flights from Bozeman (BZN) to Marion (MWA)
- Flights from Charlottesville (CHO) to Marion (MWA)
- Flights from Columbus (CMH) to Marion (MWA)
- Flights from Columbia (COU) to Marion (MWA)
- Flights from Mosinee (CWA) to Marion (MWA)
- Flights from Minneapolis (FCM) to Marion (MWA)
- Flights from Grand Forks (GFK) to Marion (MWA)
- Flights from Gulfport (GPT) to Marion (MWA)
- Flights from Lawton (LAW) to Marion (MWA)
- Flights from Harrisburg (MDT) to Marion (MWA)
- Flights from Chicago (MDW) to Marion (MWA)
- Flights from Male (MLE) to Marion (MWA)
- Flights from Mumias (MUM) to Marion (MWA)
- Flights from Orland (OLA) to Marion (MWA)
- Flights from Omaha (OMA) to Marion (MWA)
- Flights from Worcester (ORH) to Marion (MWA)
- Flights from Osh (OSS) to Marion (MWA)
- Flights from Sharjah (SHJ) to Marion (MWA)
- Flights from Sacramento (SMF) to Marion (MWA)
- Flights from Sogndal (SOG) to Marion (MWA)
- Flights from Santarem (STM) to Marion (MWA)
- Flights from Tbilisi (TBS) to Marion (MWA)
- Flights from Jinan (TNA) to Marion (MWA)
- Flights from Tangier (TNG) to Marion (MWA)
- Flights from Tampa (TPA) to Marion (MWA)
- Flights from Concord (USA) to Marion (MWA)
- Flights from Tunica (UTM) to Marion (MWA)
- Flights from Whangarei (WRE) to Marion (MWA)
- Flights from Thunder Bay (YQT) to Marion (MWA)
- Flights from Zürich (ZRH) to Marion (MWA)
- Flights from Atlanta to Du Quoin
- Flights from Detroit to Du Quoin
- Flights from Springfield to Du Quoin
- Flights from Greenville - Spartanburg to Du Quoin
- Flights from Chicago to Nashville
- Flights from Orlando to Nashville
- Flights from Atlanta to Southwest Illinois
- Flights from Houston to Southwest Illinois
- Flights from Minneapolis - St. Paul to Southwest Illinois
- Flights from Phoenix to Southwest Illinois
- Flights from Dire Dawa to Marion
- Flights from Placencia to Marion
- Flights from Gulfport to Marion
- Flights from Mae Hong Son to Marion
- Flights from Kirksville to Marion
- Flights from Anchorage to Marion
- Flights from Cleveland to Marion
- Flights from Memphis to Marion
- Flights from Philadelphia to Marion
- Flights from Salt Lake City to Marion
- Flights from Sydney to Marion
- Flights from Edmonton to Marion
- Flights from Belgrade to Marion
- Flights from Laredo to Marion
- Flights from Manus Island to Marion
- Flights from Olbia to Marion
- Flights from Pasco to Marion
- Flights from Texico to Marion
- Flights from Kilkelly to Marion
- Flights from Savusavu to Marion
- Flights from Hamilton to Marion
- Flights from Fort McMurray to Marion
- Flights from Watertown to Marion
- Flights from Gasan to Marion
- Flights from Pariñas to Marion
- Flights from Alcoa to Marion
- Flights from Myrtle Beach to Marion
- Flights from Burlington to Marion
- Flights from Toledo to Marion
- Flights from San Jose to Marion
- Flights from Bora Bora to Marion
- Flights from Eugene to Marion
- Flights from Tampa to Marion
- Flights from Lafayette to Marion
- Flights from Huangshan to Marion
- Flights from Angelholm to Marion
- Flights from Aberdeen to Marion
- Flights from Ithaca to Marion
- Flights from Jamestown to Marion
- Flights from Stavanger to Marion
- Flights from Ann Arbor to Marion
- Flights from Houghton to Marion
- Flights from Langkawi to Marion
- Flights from Nagoya to Marion
- Flights from Kitakyushu to Marion
- Flights from Terrell to Marion
- Flights from Darwin to Marion
- Flights from Hue to Marion
- Flights from San Andres del Rabanedo to Marion
- Flights from Yenisehir to Marion
- Flights from Sao Goncalo do Amarante to Marion
- Flights from Cairo to Marion
- Flights from Destin to Marion
- Flights from Clear Lake to Marion
- Flights from Mesa to Marion
- Flights from Pikeville to Marion
- Flights from Cusco to Marion
- Flights from Latham to Marion
- Flights from Apeldoorn to Marion
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.