
$70 Cheap flight deals from Houston (HOU) to Southwest Illinois (STL)
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This Weekend's Flight Deals from Houston to Southwest Illinois
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $70 One Way, $144 Round Trip from Houston to Southwest Illinois
Prices starting at $144 for return flights and $70 for one-way flights to Southwest Illinois were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Southwest Illinois economy flight packages

Hampton Inn By Hilton St Louis Airport
May 20 - May 22
Houston (HOU) to St. Louis (STL)
Reviewed on Oct 26, 2025


Hampton Inn & Suites Clayton/St. Louis-Galleria Area
May 20 - May 22
Houston (HOU) to St. Louis (STL)
Reviewed on Apr 20, 2022
More About Flying To Southwest Illinois from Houston
Route Information for Flights from Houston to Southwest Illinois
Origin Airport IATA Code | HOU |
|---|---|
Destination Airport IATA Code | STL |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Houston to Southwest Illinois
If it is not enough that we have guaranteed low prices for Houston to Southwest Illinois flights, Orbitz can also integrate your hotel and car rental needs into the package. This ensures your trip goes smoothly and you get the best possible bargain.
Save Big On Hotels With Our Summer Hotel Sale When Booking Houston to Southwest Illinois Flights
We will get you bargain air tickets for Houston to Southwest Illinois flights and can save you even more with our Summer Hotel sale. You can get a discount of up to 40% when you book a hotel along with your bargain flight from Orbitz.
If You Are Going To The Beach We Can Save You Even More
When you are arranging budget flights from Houston to Southwest Illinois, you can save even more by staying near a beach. Orbitz Beach Hotel Deals will allow you to get as much as half off the price of an already cheap hotel. Saving money has never been this fun.
Plan A Spontaneous Trip Using Our Top Hotel and Flight Destinations
Want to know where other people are staying after flights from Houston to Southwest Illinois? We not only recommend top destinations, but will tell you the most popular places to stay after {origin.name} to Southwest Illinois flights.
Use Orbitz.com For Up To The Minute Hot Deals
Budget deals on flights from Houston to Southwest Illinois are constantly changing. You can get up-to-the-minute updates on the hottest deals on discount tickets and hotels on our website.
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

