$76 Cheap flight deals from Houston (HOU) to Southwest Illinois (STL)

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This Weekend's Flight Deals from Houston to Southwest Illinois

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Apr 19 - Thu, Apr 23
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$278 Roundtrip, found 18 hours ago
$278
Roundtrip
found 18 hours ago
Select Frontier Airlines flight, departing Sun, Apr 19 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Thu, Apr 23, priced at $278 found 18 hours ago
Sun, Apr 19 - Thu, Apr 23
IAH
George Bush Intercontinental
STL
Lambert-St. Louis Intl.
$278 Roundtrip, found 18 hours ago
$278
Roundtrip
found 18 hours ago
Select Frontier Airlines flight, departing Sun, Apr 19 from George Bush Intercontinental to Lambert-St. Louis Intl., returning Thu, Apr 23, priced at $278 found 18 hours ago

Airfares from $76 One Way, $142 Round Trip from Houston to Southwest Illinois

Prices starting at $142 for return flights and $76 for one-way flights to Southwest Illinois were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, May 7 - Wed, May 13
IAH
Houston
STL
St. Louis
$142 Roundtrip, found 21 hours ago
$142
Roundtrip
found 21 hours ago
Select Frontier Airlines flight, departing Thu, May 7 from Houston to St. Louis, returning Wed, May 13, priced at $142 found 21 hours ago
Thu, May 7 - Mon, May 11
IAH
Houston
STL
St. Louis
$144 Roundtrip, found 5 hours ago
$144
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Thu, May 7 from Houston to St. Louis, returning Mon, May 11, priced at $144 found 5 hours ago
Tue, May 12 - Sat, May 16
IAH
Houston
STL
St. Louis
$154 Roundtrip, found 5 hours ago
$154
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Tue, May 12 from Houston to St. Louis, returning Sat, May 16, priced at $154 found 5 hours ago
Wed, May 6 - Tue, May 12
IAH
Houston
STL
St. Louis
$259 Roundtrip, found 21 hours ago
$259
Roundtrip
found 21 hours ago
Select American Airlines flight, departing Wed, May 6 from Houston to St. Louis, returning Tue, May 12, priced at $259 found 21 hours ago
Wed, May 6 - Tue, May 12
IAH
Houston
STL
St. Louis
$262 Roundtrip, found 21 hours ago
$262
Roundtrip
found 21 hours ago
Select United flight, departing Wed, May 6 from Houston to St. Louis, returning Tue, May 12, priced at $262 found 21 hours ago

Southwest Illinois economy flight packages

Price found within the past 48 hours. Click for updated prices.
White House at Grand Central
4.0-star property

White House at Grand Central

8.4/10 Very Good! (130 reviews)

May 27 - May 29

2 night stay

Houston (HOU) to St. Louis (STL)

Southwest Airlines • Coach

St. Louis (STL) to Houston (HOU)

Frontier Airlines • Coach
Price was $385, price is now $333 per person
$333
per person
found 4 hours ago
Beautiful old building with lots of character. Well supplied.

Reviewed on Sep 17, 2023

Country Inn & Suites by Radisson, St. Charles Historic District
2.5-star property

Country Inn & Suites by Radisson, St. Charles Historic District

9.4/10 Exceptional! (1,011 reviews)

May 27 - May 29

2 night stay

Houston (HOU) to St. Louis (STL)

Southwest Airlines • Coach

St. Louis (STL) to Houston (HOU)

Frontier Airlines • Coach
Price was $474, price is now $408 per person
$408
per person
found 4 hours ago
Great check-in and location!

Reviewed on Nov 21, 2025

Missouri Athletic Club
3.5-star property

Missouri Athletic Club

8.8/10 Excellent! (1,003 reviews)

May 27 - May 29

2 night stay

Houston (HOU) to St. Louis (STL)

Southwest Airlines • Coach

St. Louis (STL) to Houston (HOU)

Frontier Airlines • Coach
Price was $444, price is now $396 per person
$396
per person
found 4 hours ago
I needed an affordable hotel within an easy walk of the Convention Center. This property met that need; the price was reasonable compared to nearby hotels, and a leisurely walk to Americas Center took me all of ten minutes. My room was a bit tired and dated, but I wasn't there that much. There was quite a lot of overnight noise from the busy street outside, even on a high floor. There was a step up to the bathroom that could have been dangerous, no warning. Speaking as a woman who travels for business, the area around the sink and mirror were not laid out conveniently for my needs--very little space for toiletries or makeup in the bathroom, and the shelf below the mirror was one where things tended to roll off into the sink. Also, there was no full-length mirror in the room. I did not try the breakfast because it was too expensive, and on the one day I seriously considered it, it did not begin until 8 a.m. on Saturday--too late for my conference schedule. Fortunately there are options within walking distance. Similar comment about lunch and dinner: pricey, which you do not know until arrival at the hotel, since the restaurant(s) do not post their menus online. Again, there are options within walking distance. I'm still satisfied with my choice of where to stay, but I'm not sure I'd stay again; not solo-female-traveler-friendly.

Reviewed on Oct 23, 2025

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More About Flying To Southwest Illinois from Houston

Route Information for Flights from Houston to Southwest Illinois

Origin Airport IATA Code
HOU
Destination Airport IATA Code
STL
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Houston to Southwest Illinois

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.