
$34 Cheap flight deals from Denver (DEN) to Knoxville (DSM)
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This Weekend's Flight Deals from Denver to Knoxville
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $34 One Way, $66 Round Trip from Denver to Knoxville
Prices starting at $66 for return flights and $34 for one-way flights to Knoxville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Knoxville economy flight packages

Wildwood Lodge
Feb 11 - Feb 15
Denver (DEN) to Des Moines (DSM)
Des Moines (DSM) to Denver (DEN)
Reviewed on Aug 4, 2025

Holiday Inn Downtown - Mercy Area by IHG
Feb 11 - Feb 15
Denver (DEN) to Des Moines (DSM)
Des Moines (DSM) to Denver (DEN)
Reviewed on Oct 15, 2025

Hotel Fort Des Moines, Curio Collection by Hilton
Feb 11 - Feb 15
Denver (DEN) to Des Moines (DSM)
Des Moines (DSM) to Denver (DEN)
Reviewed on Nov 28, 2025
More About Flying To Knoxville from Denver
Route Information for Flights from Denver to Knoxville
Origin Airport IATA Code | DEN |
|---|---|
Destination Airport IATA Code | DSM |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Denver to Knoxville
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Flights from Denver
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Knoxville Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.
