$122 Cheap flight deals from Chicago (CHI) to La Mesa (SAN)
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This Weekend's Flight Deals from Chicago to La Mesa
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $122 One Way, $210 Round Trip from Chicago to La Mesa
Prices starting at $210 for return flights and $122 for one-way flights to La Mesa were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
La Mesa economy flight packages
Los Bungalows
Jun 25 - Jun 28
Chicago (CHI) to San Diego (SAN)
Reviewed on Apr 3, 2026
The Artifact Inn
Jul 1 - Jul 5
Chicago (CHI) to San Diego (SAN)
San Diego (SAN) to Chicago (CHI)
City24 Hotel Little Italy Mission Hills
Jul 1 - Jul 5
Chicago (CHI) to San Diego (SAN)
San Diego (SAN) to Chicago (CHI)
More About Flying To La Mesa from Chicago
Route Information for Flights from Chicago to La Mesa
Origin Airport IATA Code | CHI |
|---|---|
Destination Airport IATA Code | SAN |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Chicago to La Mesa
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Your Perfect La MesaVacation Package
Orbitz gives you access to exclusive deals and discounts on flights from Chicago to La Mesa. Mix and match hotels and Chicago to La Mesa flights to create your dream vacation. All your options are displayed at a glance with the Orbitz Matrix Display, which shows your package savings and built-in extras, such as free nights.
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Don’t Forget the Car Rental
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Low Price Guarantee
With the best deals and easy searching options, Orbitz make it easy and fun to find cheap Chicago to La Mesa flights, a great hotel, or a full vacation package. With Orbitz’s low price guarantee, you always get great discounts on air ticket prices.
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.