$33 Cheap flight deals from Chicago (CHI) to Louisburg (RDU)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Chicago to Louisburg

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Feb 15 - Wed, Feb 18
MDW
Midway Intl.
RDU
Raleigh - Durham Intl.
$278 Roundtrip, found 18 hours ago
$278
Roundtrip
found 18 hours ago
Select Frontier Airlines flight, departing Sun, Feb 15 from Midway Intl. to Raleigh - Durham Intl., returning Wed, Feb 18, priced at $278 found 18 hours ago
Sun, Feb 15 - Tue, Feb 17
ORD
O'Hare Intl.
RDU
Raleigh - Durham Intl.
$339 Roundtrip, found 4 hours ago
$339
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Sun, Feb 15 from O'Hare Intl. to Raleigh - Durham Intl., returning Tue, Feb 17, priced at $339 found 4 hours ago
Sun, Feb 15 - Thu, Feb 19
RFD
Greater Rockford
RDU
Raleigh - Durham Intl.
$709 Roundtrip, found 4 days ago
$709
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sun, Feb 15 from Greater Rockford to Raleigh - Durham Intl., returning Thu, Feb 19, priced at $709 found 4 days ago

Airfares from $33 One Way, $66 Round Trip from Chicago to Louisburg

Prices starting at $66 for return flights and $33 for one-way flights to Louisburg were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Apr 23 - Thu, Apr 30
ORD
Chicago
RDU
Raleigh
$66 Roundtrip, found 2 hours ago
$66
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Thu, Apr 23 from Chicago to Raleigh, returning Thu, Apr 30, priced at $66 found 2 hours ago
Fri, Feb 27 - Wed, Mar 4
MDW
Chicago
RDU
Raleigh
$146 Roundtrip, found 1 day ago
$146
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Feb 27 from Chicago to Raleigh, returning Wed, Mar 4, priced at $146 found 1 day ago
Sat, Apr 25 - Tue, Apr 28
ORD
Chicago
RDU
Raleigh
$164 Roundtrip, found 4 days ago
$164
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Apr 25 from Chicago to Raleigh, returning Tue, Apr 28, priced at $164 found 4 days ago
Wed, Mar 11 - Wed, Mar 18
ORD
Chicago
RDU
Raleigh
$171 Roundtrip, found 10 hours ago
$171
Roundtrip
found 10 hours ago
Select JetBlue Airways flight, departing Wed, Mar 11 from Chicago to Raleigh, returning Wed, Mar 18, priced at $171 found 10 hours ago
Thu, Apr 23 - Mon, Apr 27
ORD
Chicago
RDU
Raleigh
$177 Roundtrip, found 1 hour ago
$177
Roundtrip
found 1 hour ago
Select United flight, departing Thu, Apr 23 from Chicago to Raleigh, returning Mon, Apr 27, priced at $177 found 1 hour ago

Louisburg economy flight packages

Price found within the past 48 hours. Click for updated prices.
Unscripted Durham, Part of JDV by Hyatt
3.5-star property

Unscripted Durham, Part of JDV by Hyatt

8.2/10 Very Good! (1,002 reviews)

Mar 25 - Mar 29

4 night stay

Chicago (CHI) to Raleigh (RDU)

Frontier Airlines • Non-stop • Coach

Raleigh (RDU) to Chicago (CHI)

American Airlines • Non-stop • Coach
Price was $664, price is now $547 per person
$547
per person
found 1 day ago
Our room (201) was comfortable, clean and had nice natural lighting. The spacious bathroom and products were much appreciated. The hotel lobby could use a refresh as it didn’t match the light and brightness of the room. The garage could use a serious power wash and a repaint but it was explained to us that the garage was a separate operator from the hotel. The hotel’s central location can’t be beat.

Reviewed on Oct 1, 2025

The Longleaf Hotel
3.0-star property

The Longleaf Hotel

9.6/10 Exceptional! (1,001 reviews)

Mar 25 - Mar 29

4 night stay

Chicago (CHI) to Raleigh (RDU)

Frontier Airlines • Non-stop • Coach

Raleigh (RDU) to Chicago (CHI)

American Airlines • Non-stop • Coach
Price was $1,011, price is now $792 per person
$792
per person
found 1 day ago
The staff were absolutely lovely! We really enjoyed our stay and the rooms came with all the amenities we needed. Very clean and easy to access from the outside parking lot. Lots of restaurants and shops around. Would definitely stay here again! Thank you!

Reviewed on Nov 2, 2025

Forge at Raleigh Iron Works
2.5-star property

Forge at Raleigh Iron Works

8.6/10 Excellent! (4 reviews)

Mar 25 - Mar 29

4 night stay

Chicago (CHI) to Raleigh (RDU)

Frontier Airlines • Non-stop • Coach

Raleigh (RDU) to Chicago (CHI)

American Airlines • Non-stop • Coach
Price was $711, price is now $573 per person
$573
per person
found 1 day ago
Don't see what you're looking for?
See all available trips from Chicago to Louisburg
View all trips

More About Flying To Louisburg from Chicago

Route Information for Flights from Chicago to Louisburg

Origin Airport IATA Code
CHI
Destination Airport IATA Code
RDU
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Chicago to Louisburg

Score low fares on flights from Chicago to Louisburg with Orbitz. We make it easier than ever to find cheap Chicago to Louisburg flights with our cutting-edge mobile tools and mobile website.

Book Discount Flights From Chicago to Louisburg in Minutes

If you are looking for low cost Chicago to Louisburg flights, just skip all of the other so-called bargain travel sites, because Orbitz offers guaranteed low fares. That means you don't have to constantly scan multiple sites and hover like a vulture at your computer, hoping to score better deals through last-minute sales.

Find Bargain Chicago to Louisburg Flights With Our Convenient Tools

You benefit from more than just cheap flights from Chicago to Louisburg. Orbitz is a convenient one-stop trip planner. Research weather, attractions, and transportation options for Louisburg to help you plan your trip and decide what to pack and where to go.

Booking domestic or international air fare and accommodations with Orbitz is a snap. Use your iPad, iPhone or Android device to find discount flights from Chicago to Louisburg even while on the move, and sign up for instant email and text alerts to stay up-to-date on any delays affecting your flight. Or access m.orbitz.com via your mobile device’s Web browser.

Earn Miles through Orbitz for Your Frequent Flyer Program

You don't have to give up frequent flyer points to take advantage of our low fares. Add your frequent flyer number when you book your Chicago to Louisburg flights to receive credit for your trip.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.