
Cheap flights from GSP to RST (Greenville-Spartanburg Intl. to Rochester Intl.)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Cheap Flights from GSP to RST starting at $216 One Way, $399 Round Trip
Prices starting at $399 for return flights and $216 for one-way flights to Rochester Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Hotel Ideas near Rochester Intl.
Airport Hotels near Rochester Intl.

RUSTIC CABIN IN THE WOODS, 5 MIN TO ROCHESTER
This was a quiet little getaway spot with activities to do on the property. I would definitely book this again.
Reviewed on Jul 4, 2024

AmericInn by Wyndham Rochester
The room was newly remodeled but lacking a desk chair and coffee table. The exhaust system must have been shut down for construction as there was no good air circulation.
Reviewed on Dec 27, 2025

America's Stay Inn Stewartville
Good price, clean room.
Reviewed on Jan 29, 2026
Hotels In Rochester

Kahler Grand Hotel
Overall hospitality
Reviewed on Jan 31, 2026

AmericInn by Wyndham Rochester Near Mayo Clinic
Front desk and cleaning staff are so kind and helpful! Rooms are clean and up to date! Comfortable beds and atmosphere! Definitely stay again.
Reviewed on Jan 31, 2026

Aspen Suites
Did not have breakfast… but had awesome evening meal…quiet…clean very informed front desk…helpful
Reviewed on Jan 24, 2026
Rochester Hotels With Airport Transportation

America's Stay Inn Stewartville
Good price, clean room.
Reviewed on Jan 29, 2026

AmericInn by Wyndham Rochester
The room was newly remodeled but lacking a desk chair and coffee table. The exhaust system must have been shut down for construction as there was no good air circulation.
Reviewed on Dec 27, 2025

Aspen Select
Poor
Reviewed on Jan 31, 2026
Low Priced Rochester Hotels

Red Carpet Inn Rochester
The room was very clean as well as the entire premises. Very nice room. New toilets full bath with tub & shower, separate from sink. Very quiet and peaceful. Needs: faucet handles Tightened on both the sink and the tub. Refrigerator not cooling. Freezer seems to freeze though. Prime location next ...
Reviewed on Nov 25, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
Front desk and cleaning staff are so kind and helpful! Rooms are clean and up to date! Comfortable beds and atmosphere! Definitely stay again.
Reviewed on Jan 31, 2026

Med City Inn & Suites - Mayo Clinic Area
Very courteous staff, clean room, quiet hotel. Famous Dave's is literally attached to the hotel, so you have access by walking in, or by ordering through room service. The water pressure is very good, and the bedding is high quality.
Reviewed on Jan 29, 2026
Family Friendly Hotels in Rochester

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Families like: Kids pool, waterslide, game room, rollaway beds
Check-in staff helped us check in early. Great job good customer service
Reviewed on Jan 27, 2026

Med City Inn & Suites - Mayo Clinic Area
Families like: Indoor pools, waterslide, game room, free breakfast for the whole family
Very courteous staff, clean room, quiet hotel. Famous Dave's is literally attached to the hotel, so you have access by walking in, or by ordering through room service. The water pressure is very good, and the bedding is high quality.
Reviewed on Jan 29, 2026

Holiday Inn Express Rochester South - Mayo Area by IHG
Staff was very friendly, facilities were clean, nice breakfast area, pool area was clean. Room was very nice and large. We had no issues and will stay again at our next Mayo visit!
Reviewed on Jan 30, 2026
GSP to RST Route Info
Origin Airport | |
|---|---|
Destination Airport | |
Number Of Airlines Serving | |
Distance | |
Shortest Flight Departure Time | |
Shortest Flight Departure Date |
- Route Reviews
- Airport Locations
- More Popular Flights
- Top Trending
- Flights from Other Cities
- Flights From Other Airports
Other Flights from Greenville-Spartanburg Intl. Airport (GSP)
Other Flights to Rochester Intl. Airport (RST)
- Flights from Greenville
- Flights from Hendersonville
- Flights from Blue Ridge Mountains
- Flights from North Carolina Mountains
- Flights from Brevard
- Flights from Spartanburg
- Flights from Anderson
- Flights from Greer
- Flights from Simpsonville
- Flights from Travelers Rest
- Flights from Flat Rock
- Flights from Easley
- Asheville Regional Airport (AVL)
- Charlotte-Douglas Intl. Airport (CLT)
- Columbia Metropolitan Airport (CAE)
- Concord Regional Airport (USA)
- Augusta Regional Airport (AGS)
- Tri-Cities Regional Airport (TRI)
- McGhee Tyson Airport (TYS)
- Virginia Highlands Airport (VJI)
- DeKalb-Peachtree Airport (PDK)
- Smith Reynolds Airport (INT)
Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.
