Cheap flights from BTV to FLO (Burlington Intl. to Florence Regional)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Hotel Ideas near Florence Regional

Airport Hotels near Florence Regional

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3 out of 5
100 East Evans Street Florence Florence SC
$100 nightly
The price is $112 total per night from Feb 2 to Feb 3
$112 total
Feb 2 - Feb 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,003 reviews)
The room was clean and bed comfortable. Check in was good and staff helpful. My only complaint was in regard to a freezing rain storm that occurred overnight and it made walking to the designated parking area very treacherous. Customers walking to their cars were slipping and sliding as well as falling. ...

Reviewed on Jan 25, 2026

Hyatt Place Florence Downtown
Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3 out of 5
126 W Evans St Florence SC
$130 nightly
The price is $146 total per night from Feb 5 to Feb 6
$146 total
Feb 5 - Feb 6
Total with taxes and fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (615 reviews)
Didn't stay long enough to try any of the amenities that they offer.

Reviewed on Jan 11, 2026

Hotel Florence, Tapestry Collection by Hilton
Walking distance from one of South Carolina's top Medical centers.

Walking distance from one of South Carolina's top Medical centers.

Florence SC
$204 nightly
The price is $229 total per night from Jan 29 to Jan 30
$229 total
Jan 29 - Jan 30
Total with taxes and fees
Stay at this vacation home in Florence. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Old Greenwood Athletic Park and Drs Bruce and ...
9.8/10 Exceptional! (41 reviews)
Everything was great!

Reviewed on Nov 10, 2025

Walking distance from one of South Carolina's top Medical centers.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Florence

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road Florence SC
$85 nightly
The price is $95 total per night from Feb 8 to Feb 9
$95 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (2,260 reviews)
All

Reviewed on Jan 26, 2026

Park Inn by Radisson Florence, SC
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 out of 5
527 Woody Jones Blvd Florence SC
$96 nightly
The price is $107 total per night from Feb 1 to Feb 2
$107 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,194 reviews)
The staff was friendly and the room was clean.

Reviewed on Jan 19, 2026

Comfort Inn & Suites Florence Center Area
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street Florence SC
$70 nightly
The price is $79 total per night from Jan 27 to Jan 28
$79 total
Jan 27 - Jan 28
Total with taxes and fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,560 reviews)
Every thing was great

Reviewed on Jan 25, 2026

Howard Johnson by Wyndham Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Florence Hotels

Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

2 out of 5
2690 David H McLeod Boulevard Florence SC
$56 nightly
The price is $63 total per night from Feb 1 to Feb 2
$63 total
Feb 1 - Feb 2
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.6/10 (1,001 reviews)
Room was good. No microwave tho. Staff was very courteous and helpful

Reviewed on Jan 9, 2026

Red Roof Inn Florence - Civic Center
Budget Inn Timmonsville

Budget Inn Timmonsville

2 out of 5
2200 Cale Yarborough Highway Timmonsville SC
$61 nightly
The price is $68 total per night from Jan 27 to Jan 28
$68 total
Jan 27 - Jan 28
Total with taxes and fees
Stay at this motel in Timmonsville. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Florence Motor Speedway is located nearby.
7/10 Good! (325 reviews)
Clean room, great for price, stayed with spouse, 2 children and two pets. You can hear cars pulling in and out of this location. There was a homeless guy asking for money but you can encounter that anywhere. No bugs, no concerns. :)

Reviewed on Dec 29, 2025

Budget Inn Timmonsville
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from Feb 9 to Feb 10
$74 total
Feb 9 - Feb 10
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,004 reviews)
Breakfast could be better

Reviewed on Jan 22, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Florence

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC

3 out of 5
900 Woody Jones Blvd Florence SC
$106 nightly
The price is $118 total per night from Feb 8 to Feb 9
$118 total
Feb 8 - Feb 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,006 reviews)
Yes very clean and friendly!

Reviewed on Jan 20, 2026

Home2 Suites by Hilton Florence, SC
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 out of 5
1739 Mandeville Rd Florence SC
$101 nightly
The price is $113 total per night from Feb 2 to Feb 3
$113 total
Feb 2 - Feb 3
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (42 reviews)
Staff was great, the room was very clean and new

Reviewed on Jan 15, 2026

Spark by Hilton Florence North I-95, SC
Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 out of 5
140 Dunbarton Dr Florence SC
$66 nightly
The price is $74 total per night from Feb 9 to Feb 10
$74 total
Feb 9 - Feb 10
Total with taxes and fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,004 reviews)
Breakfast could be better

Reviewed on Jan 22, 2026

Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

BTV to FLO Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

What is the shortest flight from BTV to FLO?
Treat yourself to an in-flight vino and sink into your seat with a gripping novel or movie. With the journey from BTV to FLO taking 3 hours and 48 minutes, you'll have enough time to enjoy the flying experience.
How many hours flight from BTV to Florence Regional Airport (FLO)?
Typically, it takes 3 hours and 55 minutes to jet from BTV to FLO. Breeze through this medium-haul flight by watching TV shows or listening to audiobooks. Alternatively, why not catch up on some rest?
What airlines have the most flights from Burlington Intl. Airport (BTV) to FLO?
At the moment, there are no airlines that offer direct flights between Burlington Intl. Airport (BTV) and Florence Regional Airport. But there's a silver lining. There are loads of single or multi-stop flights available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.