
$175 Cheap flight deals from Knoxville (TYS) to Santa Rosa (SFO)
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This Weekend's Flight Deals from Knoxville to Santa Rosa
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $175 One Way, $168 Round Trip from Knoxville to Santa Rosa
Prices starting at $168 for return flights and $175 for one-way flights to Santa Rosa were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Santa Rosa economy flight packages

The Marker Union Square San Francisco
Nov 9 - Nov 14
Knoxville (TYS) to San Francisco (SFO)
San Francisco (SFO) to Knoxville (TYS)
Reviewed on Oct 6, 2024

The Donatello
Nov 9 - Nov 14
Knoxville (TYS) to San Francisco (SFO)
San Francisco (SFO) to Knoxville (TYS)
Reviewed on May 25, 2025

Parc 55 San Francisco - A Hilton Hotel
Nov 9 - Nov 14
Knoxville (TYS) to San Francisco (SFO)
San Francisco (SFO) to Knoxville (TYS)
Reviewed on Sep 28, 2025
More About Flying To Santa Rosa from Knoxville
Route Information for Flights from Knoxville to Santa Rosa
Origin Airport IATA Code | TYS |
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Destination Airport IATA Code | SFO |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Knoxville to Santa Rosa
Orbitz has your discount air ticket deals for flights from Knoxville to Santa Rosa. The guaranteed low prices from flights and hotels to car rentals and vacation packages make Orbitz the perfect travel website for budget trip planning.
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While Orbitz gives you access to cheap tickets for Knoxville to Santa Rosa flights, the travel site also offers free email, voice, or text message alerts to keep you informed of any abrupt changes or delays that affect your travel. You can even choose to have the alerts sent to up to six of your mobile or email contacts to keep your friends in the loop.
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Download the cutting-edge Orbitz app for either Android or iPhone, and use it to check on the status of your upcoming flights from Knoxville to Santa Rosa at any time. These apps also make it easy for you to book discount hotel rates in your destination city and check for deals on future Knoxville to Santa Rosa flights.
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.