$176 Cheap flight deals from Buffalo (BUF) to Santo Domingo (SDQ)

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This Weekend's Flight Deals from Buffalo to Santo Domingo

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Jun 5 - Tue, Jun 9
BUF
Buffalo Niagara Intl.
SDQ
Las Americas Intl.
$441 Roundtrip, found 10 hours ago
$441
Roundtrip
found 10 hours ago
Select Delta flight, departing Fri, Jun 5 from Buffalo Niagara Intl. to Las Americas Intl., returning Tue, Jun 9, priced at $441 found 10 hours ago

Airfares from $176 One Way, $387 Round Trip from Buffalo to Santo Domingo

Prices starting at $387 for return flights and $176 for one-way flights to Santo Domingo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Aug 1 - Sat, Aug 8
BUF
Buffalo
SDQ
Santo Domingo
$387 Roundtrip, found 2 hours ago
$387
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Aug 1 from Buffalo to Santo Domingo, returning Sat, Aug 8, priced at $387 found 2 hours ago
Tue, Dec 1 - Tue, Dec 8
BUF
Buffalo
SDQ
Santo Domingo
$392 Roundtrip, found 1 day ago
$392
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Dec 1 from Buffalo to Santo Domingo, returning Tue, Dec 8, priced at $392 found 1 day ago
Sat, Aug 1 - Sat, Aug 8
BUF
Buffalo
SDQ
Santo Domingo
$393 Roundtrip, found 2 hours ago
$393
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Sat, Aug 1 from Buffalo to Santo Domingo, returning Sat, Aug 8, priced at $393 found 2 hours ago
Tue, Oct 6 - Thu, Oct 15
BUF
Buffalo
SDQ
Santo Domingo
$396 Roundtrip, found 4 days ago
$396
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Oct 6 from Buffalo to Santo Domingo, returning Thu, Oct 15, priced at $396 found 4 days ago
Tue, Dec 1 - Tue, Dec 8
BUF
Buffalo
SDQ
Santo Domingo
$397 Roundtrip, found 1 day ago
$397
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Dec 1 from Buffalo to Santo Domingo, returning Tue, Dec 8, priced at $397 found 1 day ago

Santo Domingo economy flight packages

Price found within the past 48 hours. Click for updated prices.
Coral Costa Caribe Beach Resort - All Inclusive
4.0-star property

Coral Costa Caribe Beach Resort - All Inclusive

7.8/10 Good! (2,552 reviews)

Jul 12 - Jul 18

6 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

Southwest Airlines • Non-stop • Coach

Santo Domingo (SDQ) to Buffalo (BUF)

American Airlines • Non-stop • Coach
Save 100% on your flight
Price was $2,177, price is now $1,033 per person
$1,033
per person
found 1 day ago
I pick a barcony room I they gave me a different one . I was sun happy.

Reviewed on May 25, 2026

Bahia Principe Escape Bouganville - Adults Only - All Inclusive
4.5-star property

Bahia Principe Escape Bouganville - Adults Only - All Inclusive

8.8/10 Excellent! (2,728 reviews)

Jul 12 - Jul 18

6 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

Southwest Airlines • Non-stop • Coach

Santo Domingo (SDQ) to Buffalo (BUF)

American Airlines • Non-stop • Coach
Save 100% on your flight
Price was $2,051, price is now $1,260 per person
$1,260
per person
found 1 day ago
The room was large and beautiful. The property is easy to walk and navigate and beautiful. The staff are helpful, kind and friendly. We were impressed by them. Love that the hotel has its own song and dance! The pools were great, food was great! The entertainment was great and got visitors participating. Highly recommend!

Reviewed on May 19, 2026

Bahia Principe Escape Samaná - Adults Only
4.5-star property

Bahia Principe Escape Samaná - Adults Only

8.8/10 Excellent! (682 reviews)

Jul 12 - Jul 18

6 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

Southwest Airlines • Non-stop • Coach

Santo Domingo (SDQ) to Buffalo (BUF)

American Airlines • Non-stop • Coach
Save 100% on your flight
Price was $1,919, price is now $1,208 per person
$1,208
per person
found 1 day ago
Beautiful hotel, friendly staff, Room had an amazing view of the ocean. The food was far better then expected and alcohol selection was also good. My overall stay was amazing, got the rest i needed. I would definitely recommend the resort to anyone.

Reviewed on Dec 18, 2018

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More About Flying To Santo Domingo from Buffalo

Route Information for Flights from Buffalo to Santo Domingo

Origin Airport IATA Code
BUF
Destination Airport IATA Code
SDQ
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Buffalo to Santo Domingo

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Find Low Prices in One Place

Booking a trip from Buffalo to Santo Domingo has never been easier. Not only will you find great deals on flights, we offer bargains on cruises, car rentals, top-notch hotels, and more. You can also research and add local activities in Santo Domingo to your flight or hotel reservation to keep the kids happy and active.

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Use our mobile app for your iPhone, iPad, or Android phone—or our mobile website m.orbitz.com—to find bargains on flights from Buffalo to Santo Domingo wherever you are. Book your cheap Buffalo to Santo Domingo flights and a hotel room too—even at the last minute. Orbitz also makes your life easier with free alerts that are sent to your mobile phone or email about delays to your upcoming flights from Buffalo to Santo Domingo.

Don’t Miss out on Miles

Accumulate frequent flyer miles or points on your Buffalo to Santo Domingo flights. It’s as simple as entering your frequent flyer number when you’re making your flight reservation on Orbitz to rack up miles on qualified flights from Buffalo to Santo Domingo. You can save your frequent flyer numbers in your Orbitz account to save time during your next flight booking.

Frequently asked questions

What is the shortest flight from Buffalo to Santo Domingo?
With the journey from Buffalo Niagara Intl. Airport (BUF) to Santo Domingo Airport taking a minimum of 4 hours and 58 minutes, there's plenty of time to kick back and enjoy the ride. Treat yourself to a glass of red and get comfy in your seat with an interesting book or movie.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.