$141 Cheap flight deals from Buffalo (BUF) to Santo Domingo (SDQ)

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Airfares from $141 One Way, $365 Round Trip from Buffalo to Santo Domingo

Prices starting at $365 for return flights and $141 for one-way flights to Santo Domingo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Apr 30 - Thu, May 7
BUF
Buffalo
SDQ
Santo Domingo
$365 Roundtrip, found 22 hours ago
$365
Roundtrip
found 22 hours ago
Select United flight, departing Thu, Apr 30 from Buffalo to Santo Domingo, returning Thu, May 7, priced at $365 found 22 hours ago
Thu, Apr 30 - Thu, May 7
BUF
Buffalo
SDQ
Santo Domingo
$365 Roundtrip, found 22 hours ago
$365
Roundtrip
found 22 hours ago
Select Delta flight, departing Thu, Apr 30 from Buffalo to Santo Domingo, returning Thu, May 7, priced at $365 found 22 hours ago
Tue, Jun 2 - Sat, Jun 13
BUF
Buffalo
SDQ
Santo Domingo
$366 Roundtrip, found 2 days ago
$366
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Jun 2 from Buffalo to Santo Domingo, returning Sat, Jun 13, priced at $366 found 2 days ago
Thu, Oct 29 - Fri, Nov 6
BUF
Buffalo
SDQ
Santo Domingo
$369 Roundtrip, found 4 days ago
$369
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Oct 29 from Buffalo to Santo Domingo, returning Fri, Nov 6, priced at $369 found 4 days ago
Thu, Jul 16 - Mon, Jul 20
BUF
Buffalo
SDQ
Santo Domingo
$376 Roundtrip, found 3 days ago
$376
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Jul 16 from Buffalo to Santo Domingo, returning Mon, Jul 20, priced at $376 found 3 days ago

Santo Domingo economy flight packages

Price found within the past 48 hours. Click for updated prices.
Coral Costa Caribe Beach Resort - All Inclusive
4.0-star property

Coral Costa Caribe Beach Resort - All Inclusive

7.8/10 Good! (2,582 reviews)

May 3 - May 7

4 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $1,475, price is now $789 per person
$789
per person
found 23 hours ago
Place and staff was awesome would def be bk Food was great

Reviewed on Oct 14, 2025

Bahia Principe Grand El Portillo - All Inclusive
4.0-star property

Bahia Principe Grand El Portillo - All Inclusive

8.4/10 Very Good! (1,001 reviews)

May 14 - May 19

5 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

JetBlue Airways • Non-stop • Coach

Santo Domingo (SDQ) to Buffalo (BUF)

Delta • Non-stop • Coach
Save 100% on your flight
Price was $1,646, price is now $1,009 per person
$1,009
per person
found 1 day ago
The food options were not great at the restaurants. Entertainment staff worked hard and did a good job for all the guests Bartenders at the pool bar were great. Chef at Boho were great

Reviewed on Jan 31, 2024

Viva V Samana by Wyndham, A Trademark Adults All Inclusive
4.5-star property

Viva V Samana by Wyndham, A Trademark Adults All Inclusive

7.8/10 Good! (1,004 reviews)

May 18 - May 23

5 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

Delta • Non-stop roundtrip • Coach
Price was $1,558, price is now $1,015 per person
$1,015
per person
found 1 day ago
The hotel and the beach location are quite nice, the employees at the restaurants and the bars are very dedicated and friendly and the drinks at the bars are quite good. There are three theme restaurants, we tried a variety of dishes but based on the quality of the food and service, I would only recommend the Fusion restaurant at the the lobby. There is plenty of food options at the buffet, although most of the dishes are average....pizza quality is very good. However, per comparison to similar resorts in DR the night entertainment offering is quite limited, especially at night. The entertainment team does their best, but it is very noticeable that they operate with very limited resources to be able to provide watch-worthy night entertainment for guests. That is quite important as there are not other sources for nightlife or entertainment for miles around the hotel. Even a the night club, musical rhythms are mainly local not catering to their diverse international customer base.

Reviewed on Aug 12, 2025

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More About Flying To Santo Domingo from Buffalo

Route Information for Flights from Buffalo to Santo Domingo

Origin Airport IATA Code
BUF
Destination Airport IATA Code
SDQ
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Buffalo to Santo Domingo

If you feel you cannot afford the costs involved to your dream trip to a local or international destination happen, think again! Orbitz gives you incredible deals on flights from Buffalo to Santo Domingo. Now you can book guaranteed low fares for Buffalo to Santo Domingo flights and plan your trip with confidence.

Great deals on flights from Buffalo to Santo Domingo

Cheap airfares on Buffalo to Santo Domingo flights allow you to stick to your budget and still have a great trip. We give you guaranteed low prices and make it easy to research and book discount flights using our website. Additionally, you can add your frequent flyer numbers to your Orbitz account profile, and this information will automatically be included on all your future reservations for qualified flights from Buffalo to Santo Domingo.

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Buffalo to Santo Domingo flights at discounted rates

Finding flights at the right prices can be difficult if you are not sure where to look. Don’t ruin your trip by spending more on your flights than your budget allows. Orbitz gives you guaranteed low fares on Buffalo to Santo Domingo flights and amazing discount offers on car rentals, hotels, and even fun activities in your destination. Your dream trip is more affordable than ever with Orbitz.

Frequently asked questions

What is the shortest flight from Buffalo to Santo Domingo?
With the journey from Buffalo Niagara Intl. Airport (BUF) to Santo Domingo Airport taking a minimum of 4 hours and 58 minutes, there's plenty of time to kick back and enjoy the ride. Treat yourself to a glass of red and get comfy in your seat with an interesting book or movie.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.