$201 Cheap flight deals from Buffalo (BUF) to Santo Domingo (SDQ)

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Airfares from $201 One Way, $436 Round Trip from Buffalo to Santo Domingo

Prices starting at $436 for return flights and $201 for one-way flights to Santo Domingo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Sep 8 - Wed, Sep 9
BUF
Buffalo
SDQ
Santo Domingo
$436 Roundtrip, found 5 days ago
$436
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Sep 8 from Buffalo to Santo Domingo, returning Wed, Sep 9, priced at $436 found 5 days ago
Mon, Jan 11 - Fri, Jan 29
BUF
Buffalo
SDQ
Santo Domingo
$442 Roundtrip, found 1 day ago
$442
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Jan 11 from Buffalo to Santo Domingo, returning Fri, Jan 29, priced at $442 found 1 day ago
Sat, May 8 - Fri, May 14
BUF
Buffalo
SDQ
Santo Domingo
$450 Roundtrip, found 20 hours ago
$450
Roundtrip
found 20 hours ago
Select Delta flight, departing Sat, May 8 from Buffalo to Santo Domingo, returning Fri, May 14, priced at $450 found 20 hours ago
Thu, Oct 29 - Wed, Nov 4
BUF
Buffalo
SDQ
Santo Domingo
$463 Roundtrip, found 1 day ago
$463
Roundtrip
found 1 day ago
Select JetBlue Airways flight, departing Thu, Oct 29 from Buffalo to Santo Domingo, returning Wed, Nov 4, priced at $463 found 1 day ago
Sat, Sep 26 - Thu, Oct 1
BUF
Buffalo
SDQ
Santo Domingo
$473 Roundtrip, found 4 days ago
$473
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Sat, Sep 26 from Buffalo to Santo Domingo, returning Thu, Oct 1, priced at $473 found 4 days ago

Santo Domingo economy flight packages

Price found within the past 48 hours. Click for updated prices.
Bahia Principe Escape Bouganville - Hyatt Inclusive Collection - Adults Only - All Inclusive
4.5-star property

Bahia Principe Escape Bouganville - Hyatt Inclusive Collection - Adults Only - All Inclusive

8.8/10 Excellent! (2,669 reviews)

Sep 11 - Sep 14

3 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

Delta • Non-stop roundtrip • Coach
Price was $1,250, price is now $846 per person
$846
per person
found 1 day ago
NOT 420 Friendly!! The pool temperature was disgustingly hot! I understand it’s July, but the pool water was as hot as the hot tub. The lagoon water had jellyfish. I’m familiar with other resorts and travel months and they have been cooler and refreshing! When you arrive you’re forced to make dinner reservations for your entire trip if you want to go to one of the restaurants. Because of this limitation we gave 4 stars in the hotel lobby kiosk. AND SOME OF THEM THEY HAVE KIDS AT THEM! The very next morning- they woke us up with a call asking how to get that 5th star?? The entertainment was so so. They did a disco night and none of the entertainment team knew how to dance it; however, they had the Dance Fever motion down. Spanish is the language. Very few people speak English.

Reviewed on Aug 8, 2026

Bahia Principe Explore La Romana - Hyatt Inclusive Collection - All Inclusive
4.5-star property

Bahia Principe Explore La Romana - Hyatt Inclusive Collection - All Inclusive

8.4/10 Very Good! (2,680 reviews)

Sep 17 - Sep 22

5 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

American Airlines • Non-stop roundtrip • Coach
Price was $1,865, price is now $1,329 per person
$1,329
per person
found 1 day ago

Casa Black and White. Vista al Mar
5.0-star property

Casa Black and White. Vista al Mar

No reviews

Sep 17 - Sep 22

5 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

American Airlines • Non-stop roundtrip • Coach
Price was $3,189, price is now $2,851 per person
$2,851
per person
found 1 day ago

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More About Flying To Santo Domingo from Buffalo

Route Information for Flights from Buffalo to Santo Domingo

Origin Airport IATA Code
BUF
Destination Airport IATA Code
SDQ
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Buffalo to Santo Domingo

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Frequently asked questions

What is the shortest flight from Buffalo to Santo Domingo?
With the journey from Buffalo Niagara Intl. Airport (BUF) to Santo Domingo Airport taking a minimum of 4 hours and 58 minutes, there's plenty of time to kick back and enjoy the ride. Treat yourself to a glass of red and get comfy in your seat with an interesting book or movie.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.