$178 Cheap flight deals from Buffalo (BUF) to Santo Domingo (SDQ)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Airfares from $178 One Way, $386 Round Trip from Buffalo to Santo Domingo
Prices starting at $386 for return flights and $178 for one-way flights to Santo Domingo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Santo Domingo economy flight packages
Coral Costa Caribe Beach Resort - All Inclusive
Jun 12 - Jun 19
Buffalo (BUF) to Santo Domingo (SDQ)
Santo Domingo (SDQ) to Buffalo (BUF)
Reviewed on Oct 14, 2025
Bahia Principe Explore El Portillo - All Inclusive
Jun 21 - Jun 27
Buffalo (BUF) to Santo Domingo (SDQ)
Reviewed on Jan 31, 2024
Bahia Principe Escape Samaná - Adults Only
Jun 12 - Jun 19
Buffalo (BUF) to Santo Domingo (SDQ)
Santo Domingo (SDQ) to Buffalo (BUF)
Reviewed on Dec 18, 2018
More About Flying To Santo Domingo from Buffalo
Route Information for Flights from Buffalo to Santo Domingo
Origin Airport IATA Code | BUF |
|---|---|
Destination Airport IATA Code | SDQ |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Buffalo to Santo Domingo
Orbitz On-the-Go is your one-stop shop for discount vacation air travel. Our cutting-edge mobile tools leave you time to pack for the trip. Shop our sales on domestic flights from Buffalo to Santo Domingo.
Best Bargains Anywhere
Cheap vacations start at Orbitz On-the-Go. Find the best deals on international flights from Buffalo to Santo Domingo.
Complete Travel Planning
Your phone becomes a full-service vacation travel agency with Orbitz mobile phone apps. From reservations to arrivals, every detail is in the palm of your hand. Book budget flights from Buffalo to Santo Domingo; add a car and hotel, share your itinerary and keep up with changes. Orbitz apps cover all the bases for you.
Totally Stress-Free
Free Alerts from Orbitz On-the-Go keep your vacation free from worry. Free Alerts updates you the moment any changes occur. You’ll always have the most current flight, gate and baggage claim details. So sit back and enjoy your low fare on Buffalo to Santo Domingo flights.
More Miles Faster = Maximum Value
Orbitz On-the-Go securely stores your frequent flier and loyalty program information. Watch your miles add up when you book discount Buffalo to Santo Domingo flights with Orbitz. Make your vacation mileage-friendly with low cost air tickets on Buffalo to Santo Domingo flights. Orbitz is your destination for vacation value.
Frequently asked questions
- Flights to Santo Domingo
- Flights from Buffalo
- Buffalo Airports
- Santo Domingo Airports
- Airlines Operating
Flights to Santo Domingo
- New York to Santo Domingo
- Fort Lauderdale to Santo Domingo
- Toronto to Santo Domingo
- Orlando to Santo Domingo
- Chicago to Santo Domingo
- Houston to Santo Domingo
- Detroit to Santo Domingo
- New Orleans to Santo Domingo
- Washington to Santo Domingo
- San Francisco to Santo Domingo
- Buenos Aires to Santo Domingo
- Paris to Santo Domingo
- São Paulo to Santo Domingo
- San José to Santo Domingo
- Bucaramanga to Santo Domingo
Flights from Buffalo
- Buffalo to Orlando
- Buffalo to New York
- Buffalo to Atlanta
- Buffalo to Houston
- Buffalo to Chicago
- Buffalo to Dallas
- Buffalo to Los Angeles
- Buffalo to New Orleans
- Buffalo to Phoenix
- Buffalo to Charlotte
- Buffalo to Washington
- Buffalo to Toronto
- Buffalo to Rome
- Buffalo to San Francisco
- Buffalo to Detroit
- Buffalo to Hartford
- Buffalo to Kansas City
- Buffalo to London
- Buffalo to Montreal
- Buffalo to Sacramento
Buffalo Airports
Santo Domingo Airports
More Destinations
- Hotels near Plaza de la Bandera
- Villa Mella Hotels
- Ensanche Isabelita Hotels
- Apartments in Santo Domingo Este
- Extended Stay Hotels in Santo Domingo Este
- Hotels with Kitchenettes in Santo Domingo Este
- Romantic Getaways & Hotels in Santo Domingo Este
- Hotels with a Wedding Venue in Santo Domingo Este
- Santo Domingo Este Hotels
- Villas in Santo Domingo Este
- Hotels near Assembly Hall of Jehovah's Witnesses
- Hotels near Zona Franca de San Isidro Industrial Area
- Hotels near Megacentro Mall
- Guest Houses in Mama Tingo Station
- Hotels near Las Americas Intl.
- Hotels near Caucedo Port
- Apartments in Santo Domingo Oeste
- Condo Rentals in Santo Domingo Oeste
- Hostels in Santo Domingo Oeste
- Santo Domingo Oeste Hotels
- Villas in Santo Domingo Oeste
- Hotels near Agua Splash Caribe Parque Acuatico
- Hotels near La Caleta Park
- Extended Stay Hotels in Boca Chica
- All Inclusive Resorts & in Boca Chica
- Beach Resorts & in Boca Chica
- Casino Resorts & in Boca Chica
- Golf Resorts & in Boca Chica
- Hotels with Bar in Boca Chica
- Hotels with Hot Tubs in Boca Chica
- Hotels with Waterslides in Boca Chica
- Luxury Hotels in Boca Chica
- Waterpark Hotels & Resorts in Boca Chica
- Hotels with a Wedding Venue in Boca Chica
- Boca Chica Hotels
- Residencial Santo Domingo Hotels
- Los Frailes Hotels
- Hotels near Boca Chica Beach
- Hotels near Dream Casino Be Live Hamaca
- All Inclusive Resorts & in Santo Domingo
- Romantic Getaways & Hotels in Santo Domingo
- Waterpark Hotels & Resorts in Santo Domingo
- Santo Domingo Hotels
- Hotels near Hipódromo V Centenario
- Flights from Las Americas Intl.
- Flights from Newark Liberty Intl. Airport (EWR) to Santo Domingo (SDQ)
- Flights from New York (JFK) to Santo Domingo (SDQ)
- Flights from Kingston (KIN) to Santo Domingo (SDQ)
- Flights from Miami (MIA) to Santo Domingo (SDQ)
- Flights from Port-au-Prince (PAP) to Santo Domingo (SDQ)
- Flights from San Juan (SJU) to Santo Domingo (SDQ)
- Flights from La Isabela Intl.
- Flights to Boca Chica
- Flights from Boca Chica
- Flights to Santo Domingo
- Flights from Santo Domingo
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.