
$125 Cheap flight deals from Pittsburgh (PIT) to Des Moines (SEA)
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This Weekend's Flight Deals from Pittsburgh to Des Moines
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $125 One Way, $255 Round Trip from Pittsburgh to Des Moines
Prices starting at $255 for return flights and $125 for one-way flights to Des Moines were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Des Moines economy flight packages

Marriott Tacoma Downtown
Jun 23 - Jun 26
Pittsburgh (PIT) to Seattle (SEA)
Seattle (SEA) to Pittsburgh (PIT)
Reviewed on Aug 4, 2025

Ändra Hotel Seattle - MGallery Collection
Jun 23 - Jun 26
Pittsburgh (PIT) to Seattle (SEA)
Seattle (SEA) to Pittsburgh (PIT)
Reviewed on Jan 26, 2026

Kimpton Palladian Hotel by IHG
Jun 23 - Jun 26
Pittsburgh (PIT) to Seattle (SEA)
Seattle (SEA) to Pittsburgh (PIT)
Reviewed on Jul 16, 2024
More About Flying To Des Moines from Pittsburgh
Route Information for Flights from Pittsburgh to Des Moines
Origin Airport IATA Code | PIT |
|---|---|
Destination Airport IATA Code | SEA |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Pittsburgh to Des Moines
The best fares for Pittsburgh to Des Moines flights are always found on Orbitz. With superior discounts and the latest innovations in mobile access, your ideal trip starts with Orbitz.
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We provide access to many low-cost vacation packages and travelers can mix and match airlines when scheduling their flights for the best prices and flight times. Finding cheap tickets on flights from Pittsburgh to Des Moines is easy when you make Orbitz your #1 travel planner.
Book Pittsburgh to Des Moines Flights With Mobile Apps
Our iPhone and Android mobile apps can be used to compare and book flights from Pittsburgh to Des Moines. These apps are perfect for checking the status of flights, gate and baggage claims details, car rental rates, and for receiving alerts on special savings that are exclusive to mobile users. Mobile app users can even score great rates when booking hotel rooms. You can compare hotels, virtually view photo galleries, and check out user reviews using the app, as well as find out which ones are closest to you.
Orbitz also offers free travel updates that are sent to your email or mobile phone that notifies you of booking changes, disruptions in service, or delayed flights.
Increase Your Rewards While Enjoying Super Low Rates
Boost your points or miles for your frequent flyer program on certain Pittsburgh to Des Moines flights. Simply provide your frequent flyer information when booking flights from Pittsburgh to Des Moines with Orbitz and get both a low fare and travel rewards. You can enter this information in your Orbitz account profile for easy remembering in future bookings.
Flights from Pittsburgh
- Pittsburgh to Las Vegas
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- Pittsburgh to Charlotte
- Pittsburgh to Washington
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Pittsburgh Airports
Des Moines Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.



