$167 Cheap flight deals from Boston (BOS) to Knoxville (DSM)

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This Weekend's Flight Deals from Boston to Knoxville

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Jul 3 - Sat, Jul 4
BOS
Logan Intl.
DSM
Des Moines Intl.
$380 Roundtrip, found 5 days ago
$380
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Jul 3 from Logan Intl. to Des Moines Intl., returning Sat, Jul 4, priced at $380 found 5 days ago

Airfares from $167 One Way, $341 Round Trip from Boston to Knoxville

Prices starting at $341 for return flights and $167 for one-way flights to Knoxville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Jul 22 - Wed, Jul 29
PVD
Providence
DSM
Des Moines
$341 Roundtrip, found 4 days ago
$341
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Jul 22 from Providence to Des Moines, returning Wed, Jul 29, priced at $341 found 4 days ago
Wed, Jul 22 - Wed, Jul 29
PVD
Providence
DSM
Des Moines
$374 Roundtrip, found 4 days ago
$374
Roundtrip
found 4 days ago
Select United flight, departing Wed, Jul 22 from Providence to Des Moines, returning Wed, Jul 29, priced at $374 found 4 days ago
Wed, Jul 22 - Wed, Jul 29
PVD
Providence
DSM
Des Moines
$387 Roundtrip, found 4 days ago
$387
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Jul 22 from Providence to Des Moines, returning Wed, Jul 29, priced at $387 found 4 days ago
Wed, Jul 22 - Wed, Jul 29
PVD
Providence
DSM
Des Moines
$392 Roundtrip, found 4 days ago
$392
Roundtrip
found 4 days ago
Select Delta flight, departing Wed, Jul 22 from Providence to Des Moines, returning Wed, Jul 29, priced at $392 found 4 days ago
Fri, Aug 7 - Sat, Aug 8
BOS
Boston
DSM
Des Moines
$396 Roundtrip, found 3 days ago
$396
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Aug 7 from Boston to Des Moines, returning Sat, Aug 8, priced at $396 found 3 days ago

Knoxville economy flight packages

Price found within the past 48 hours. Click for updated prices.
Sonesta Simply Suites Des Moines
2.5-star property

Sonesta Simply Suites Des Moines

8.2/10 Very Good! (1,007 reviews)

Jul 30 - Aug 3

4 night stay

Boston (BOS) to Des Moines (DSM)

United • Non-stop roundtrip • Coach
Price was $780, price is now $688 per person
$688
per person
found 18 hours ago
There were a couple hiccups during this stay but it was a value place so overlooked them. It certainly wasn’t cleaned well.. there were dark hairs in the bathroom. And the first room I had had a clogged toilet so I had to move. I had some sort of bug bites from being there, not bedbugs, but I don’t know what it was. I had itchy bug bites on my back. Not sure I will stay at these types of places again- there’s a mix of travelers and maybe some ghetto people who lost their lease. The 1st room I had had a fist punch in the bathroom door. Overall, it’s a value stay so you get what you get. The staff was friendly and helpful.

Reviewed on Jun 17, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
4.5-star property

Hotel Fort Des Moines, Curio Collection by Hilton

9.6/10 Exceptional! (1,202 reviews)

Jul 30 - Aug 3

4 night stay

Boston (BOS) to Des Moines (DSM)

United • Non-stop roundtrip • Coach
Price was $1,222, price is now $1,043 per person
$1,043
per person
found 18 hours ago
Fantastic property and such a cool historical elegance. The staff is super helpful and the rooms are very clean, spacious and the perfect place to rest after a long travel day. Very conveniently located to food, Starbucks and sights.

Reviewed on Jun 26, 2026

Hyatt Place West Des Moines Jordan Creek
3.0-star property

Hyatt Place West Des Moines Jordan Creek

9.2/10 Wonderful! (1,000 reviews)

Jul 30 - Aug 3

4 night stay

Boston (BOS) to Des Moines (DSM)

United • Non-stop roundtrip • Coach
Price was $1,056, price is now $934 per person
$934
per person
found 18 hours ago
This property was incredibly comfortable and convenient for visiting family in the area. I would absolutely stay here again. The pool was even awesome for adults.

Reviewed on Jul 7, 2025

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More About Flying To Knoxville from Boston

Route Information for Flights from Boston to Knoxville

Origin Airport IATA Code
BOS
Destination Airport IATA Code
DSM
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.