Holiday Inn Express & Suites St. Louis South - I-55 by IHG
Hotel in St. Louis with a 24-hour fitness center and an indoor pool
Choose dates to view prices
Photo gallery for Holiday Inn Express & Suites St. Louis South - I-55 by IHG





Reviews
9.6 out of 10
Exceptional
Popular amenities
Explore the area

4250 Midamerica Lane, St. Louis, MO, 63129
- Place, Barnes Jewish South Campus5 min walk
- Place, Busch Stadium16 min drive
- Place, St. Louis Union Station18 min drive
- Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)30 min drive
Room options
View all photos for Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)
9.4 out of 10
Exceptional
(13 reviews)
View all photos for Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

Standard Room, 2 Queen Beds, Accessible (Mobil Tub)
9.6 out of 10
Exceptional
(4 reviews)
View all photos for Suite, 1 Bedroom (2 Queen, Extra Living Area)

Suite, 1 Bedroom (2 Queen, Extra Living Area)
9.4 out of 10
Exceptional
(27 reviews)
View all photos for Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)
9.0 out of 10
Wonderful
(7 reviews)
View all photos for Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)
10.0 out of 10
Exceptional
(2 reviews)
View all photos for Suite, 1 King Bed (Extra Living, Walk in Shwr)

Suite, 1 King Bed (Extra Living, Walk in Shwr)
9.0 out of 10
Wonderful
(4 reviews)
View all photos for Standard Room, 1 King Bed (Bath Shwr Combo)

Standard Room, 1 King Bed (Bath Shwr Combo)
9.8 out of 10
Exceptional
(15 reviews)
View all photos for Standard Room

Standard Room
View all photos for Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)
View all photos for Standard Room, 2 Queen Beds

Standard Room, 2 Queen Beds
9.4 out of 10
Exceptional
(72 reviews)
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9.4 out of 10, Exceptional, 1,003 reviews
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The price is $126
Feb 1 - Feb 2
Total with taxes and fees
About the neighborhood
About this property
Holiday Inn Express & Suites St. Louis South - I-55 by IHG
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- Pool
- Breakfast included
- Parking included
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Feb 8 - Feb 9
Total with taxes and fees
Property amenities
Room amenities
Policies
Important information
Frequently asked questions
Holiday Inn Express & Suites St. Louis South - I-55 by IHG Reviews
Reviews
9.6
Exceptional
9.6/10
Cleanliness
9.6/10
Staff & service
9.6/10
Amenities
9.6/10
Property conditions & facilities
Reviews
Oct 22, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 4 nights in Oct 2025
10/10 Excellent
Chena
Business traveler
Oct 19, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Chena
Stayed 2 nights in Oct 2025
10/10 Excellent
phillip
Traveled with family
Oct 16, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
phillip
Stayed 3 nights in Oct 2025
10/10 Excellent
Ashley
Traveled with family
Oct 13, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Ashley
Stayed 3 nights in Oct 2025
6/10 Okay
Tera
Oct 10, 2025
Tera
Stayed 2 nights in Oct 2025
10/10 Excellent
John C
Business traveler
Oct 7, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
John C
Stayed 2 nights in Sep 2025
10/10 Excellent
Jacob
Sep 28, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Jacob
Stayed 2 nights in Sep 2025
10/10 Excellent
Diane
Traveled with family
Sep 26, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Diane
Stayed 1 night in Sep 2025
10/10 Excellent
Sarah
Sep 22, 2025
Sarah
Stayed 2 nights in Sep 2025
10/10 Excellent
Danielle
Traveled with family
Sep 21, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Best Hotel Ever
Danielle
Stayed 1 night in Sep 2025
10/10 Excellent
Merideth
Sep 19, 2025
Merideth
Stayed 1 night in Sep 2025
10/10 Excellent
Tamika
Traveled with family
Sep 18, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Tamika
Stayed 2 nights in Sep 2025
8/10 Good
Anand
Sep 16, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Anand
Stayed 1 night in Sep 2025
10/10 Excellent
Marilyn
Traveled with family
Sep 5, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Comfortable & Relaxing
Marilyn
Stayed 1 night in Sep 2025
10/10 Excellent
Maria
Traveled with family
Sep 3, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Maria
Stayed 1 night in Sep 2025
10/10 Excellent
Kaylee
Sep 1, 2025
Kaylee
Stayed 1 night in Aug 2025
8/10 Good
Laura
Sep 1, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great place!
Laura
Stayed 2 nights in Aug 2025
8/10 Good
margaret
Traveled with group
Aug 31, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Good stay!
margaret
Stayed 1 night in Aug 2025
10/10 Excellent
Verified traveler
Traveled with family
Aug 29, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Verified traveler
Stayed 2 nights in Aug 2025
10/10 Excellent
Marilyn
Traveled with family
Aug 29, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Clean, fast, & friendly!
Marilyn
Stayed 1 night in Aug 2025
8/10 Good
Francis
Traveled with family
Aug 22, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Francis
Stayed 1 night in Aug 2025
10/10 Excellent
Cresley
Traveled with family and small children, Traveled with family
Aug 19, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Cresley
Stayed 1 night in Aug 2025
8/10 Good
James
Aug 18, 2025
James
Stayed 2 nights in Aug 2025
10/10 Excellent
Linda
Aug 18, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Linda
Stayed 1 night in Aug 2025
10/10 Excellent
Tameka, Memphis
Traveled with family
Aug 15, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Tameka
Stayed 1 night in Aug 2025
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