Holiday Inn Express & Suites St. Louis South - I-55 by IHG

2.5 star property

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Photo gallery for Holiday Inn Express & Suites St. Louis South - I-55 by IHG

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Parking included
  • Free WiFi
  • Air conditioning

Explore the area

View in a map
4250 Midamerica Lane, St. Louis, MO, 63129
  • Place, Busch Stadium
    ‪16 min drive‬
  • Place, St. Louis Union Station
    ‪18 min drive‬
  • Place, St. Louis Zoo
    ‪23 min drive‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪29 min drive‬

Room options

Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

9.4 out of 10
Exceptional
(13 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

9.6 out of 10
Exceptional
(4 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

Suite, 1 Bedroom (2 Queen, Extra Living Area)

9.6 out of 10
Exceptional
(32 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free WiFi

Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

9.0 out of 10
Wonderful
(7 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

10.0 out of 10
Exceptional
(2 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free WiFi

Suite, 1 King Bed (Extra Living, Walk in Shwr)

9.2 out of 10
Wonderful
(5 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

Standard Room, 1 King Bed (Bath Shwr Combo)

9.6 out of 10
Exceptional
(18 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

Standard Room

  • 300 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 Twin Bed
  • Free WiFi

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

Standard Room, 2 Queen Beds

9.6 out of 10
Exceptional
(79 reviews)
  • 300 sq ft
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free WiFi

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About the neighborhood

St. Louis

Located within a leisurely stroll of Barnes Jewish South Campus, Holiday Inn Express & Suites St. Louis South - I-55 by IHG is within a few miles (5 km) of St Anthony's. This 99-room hotel has free breakfast along with conveniences like an indoor pool and a 24-hour gym.

What's nearby

  • Busch Stadium - 16 min drive - 17.3 miles
  • Gateway Arch - 17 min drive - 17.8 miles
  • St. Louis Union Station - 18 min drive - 17.4 miles
  • Forest Park - 20 min drive - 20.2 miles
  • St. Louis Zoo - 23 min drive - 22.2 miles

Getting around

  • Kirkwood Station - 17 min drive
  • St. Louis Lambert Intl. Airport (STL) - 32 min drive

Restaurants

  • ‪Burger King - ‬11 min walk
  • ‪Popeyes Louisiana Kitchen - ‬4 min walk
  • ‪Hardee's / Red Burrito - ‬11 min walk
  • ‪Rich & Charlie's Italian Restaurant - ‬3 min drive
  • ‪Taco Bell - ‬11 min walk

About this property

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Guests staying at Holiday Inn Express & Suites St. Louis South - I-55 by IHG enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include meeting rooms, a business center, and a banquet hall.
49-inch flat-screen TVs come with cable channels, and guests can stay connected with free WiFi and wired Internet. Bathrooms have hair dryers and free toiletries. Refrigerators, microwaves, and coffee makers are also available. Housekeeping is available on request.
Recreational amenities at the hotel include an indoor pool and a 24-hour fitness center.

Similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 9:30 AM

Things to do

  • 24-hour gym
  • Indoor pool

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • Indoor pool

Conveniences

  • 24-hour front desk
  • Safe at front desk
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Housekeeping (daily)

Business services

  • Business center
  • Meeting rooms

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Stair-free path to entrance
  • Visual alarms in hallways
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible van parking

More

  • 4 floors
  • Banquet hall
  • No plastic drinking straws
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 49-inch flat-screen TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: 2:30 AM
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Service animals exempt from fees

Children and extra beds

  • Free cribs/infant beds are available

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
  • Check-in: 3:00 PM
  • Check-out: 11 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day. Driving? This property offers free parking.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • Onsite safety features include a fire extinguisher.
  • This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

Additional information about polices, regulations, and more:

  • Pool access available from 8 AM to 10 PM.
  • Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express St. Louis South I-55 Hotel
Holiday Inn Express St. Louis South I-55
Inn Express St Louis I55
Holiday Inn Express Suites St. Louis South I 55
Holiday Inn Express Suites St. Louis South I 55 by IHG
Holiday Inn Express Suites St. Louis South I 55 an IHG Hotel
Holiday Inn Express & Suites St. Louis South - I-55 by IHG Hotel

Frequently asked questions

Is a free cancellation option available at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Holiday Inn Express & Suites St. Louis South - I-55 by IHG offers free cancellation on select room rates. To learn more, take a look at the cancellation policy on our site.

How much does it cost to stay at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

As of Jul 3, 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express & Suites St. Louis South - I-55 by IHG on Aug 2, 2026 start from $136, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What is there to do close to Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

This hotel is located in St. Louis, close to Grant's Farm, River City Casino, and Jefferson Barracks Historic Park. You'll also find Meramec River and Suson Park within a short drive.

Is parking available on site at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Yes, self parking is offered for free at the hotel. Wheelchair-accessible van parking is also available for guests.

Does Holiday Inn Express & Suites St. Louis South - I-55 by IHG include a casino at the property?

No, Holiday Inn Express & Suites St. Louis South - I-55 by IHG doesn't have a casino.

Will I find an indoor pool at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Yes, this hotel has an indoor pool. Guests have pool access between 8 AM and 10 PM.

Is Holiday Inn Express & Suites St. Louis South - I-55 by IHG a good place to stay for couples?

Couples staying at this hotel will appreciate amenities like free wired internet as well as an indoor pool and a free daily breakfast.

Are there hot tubs at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

No, this hotel doesn't have a spa tub.

Does Holiday Inn Express & Suites St. Louis South - I-55 by IHG feature a restaurant that includes a breakfast menu?

Holiday Inn Express & Suites St. Louis South - I-55 by IHG offers free buffet breakfast each morning though there is no restaurant.

Will Holiday Inn Express & Suites St. Louis South - I-55 by IHG allow pets to stay for free?

No, pets aren't allowed at Holiday Inn Express & Suites St. Louis South - I-55 by IHG though service animals are welcome.

Are there connecting rooms at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

Yes, this hotel has connecting rooms you can book for your group event or vacation.

What is the closest airport to Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

The closest major airport to Holiday Inn Express & Suites St. Louis South - I-55 by IHG is St. Louis Lambert Intl. Airport (STL), which is 26.1 mi away (32 minutes by car). Another top airport is St. Louis, MO (SUS-Spirit of St. Louis), which is located 26.2 mi away (32-minute drive).

Are there rooms with balconies that I can book at Holiday Inn Express & Suites St. Louis South - I-55 by IHG?

No, there aren't any guestrooms with balconies at Holiday Inn Express & Suites St. Louis South - I-55 by IHG.

Holiday Inn Express & Suites St. Louis South - I-55 by IHG Reviews

Reviews

9.6

Exceptional

Rating 10 - Excellent. 802 out of 1001 reviews
Rating 8 - Good. 141 out of 1001 reviews
Rating 6 - Okay. 36 out of 1001 reviews
Rating 4 - Poor. 15 out of 1001 reviews
Rating 2 - Terrible. 7 out of 1001 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.6/10

Amenities

9.6/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Adam

Liked: Cleanliness, amenities, property conditions & facilities
Great stay
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Jamie

Liked: Cleanliness, staff & service
Clean room, friendly staff.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Kelsey

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Desk staff was very friendly, room was nice and clean, kids loved the pool, breakfast was great!
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

ARIANNE

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Brand new hotel great beds and quiet despite it being sold out the night we stayed.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Megan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great breakfast, location was ideal for activities in St Louis, complimentary parking and warm cookies at night!
Stayed 4 nights in Mar 2026
Verified

10/10 Excellent

George

Liked: Cleanliness, staff & service, amenities
Clean rooms, great friendly staff, very good breakfast with lots to choose from
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

HEATHER

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The place was clean, the pool was functional, the food was decent, and my kids favorite part was the cookie hour! Will definitely pick this hotel when we come back to the St Louis area!
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff was so kind and helpful. Breakfast was delicious. We really loved the fluffy scrambled eggsa and the bean to brew coffee machine. Will definitely stay again.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Mary

Liked: Cleanliness, staff & service, amenities
The room is clean, the bed and pillows are super comfy and the breakfast is great! I travel to the area a few times a year for work and this is my new favorite place to stay.
Stayed 4 nights in Feb 2026
Verified

10/10 Excellent

Mitch

Liked: Cleanliness, staff & service, property conditions & facilities
It was great!
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Janice

Liked: Cleanliness, staff & service, amenities
Enjoyed the cleanliness and comfort of the bed and room and the friendly staffand the freshly roasted coffeecofrrroascoffee
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

James

Clean room, location, excellent staff
Stayed 4 nights in Dec 2025
Verified

10/10 Excellent

Anita

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was clean and staff was friendly.
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

Jessica

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The breakfast was fresh, hot, and delicious. Various choices from cinnamon rolls and pancakes to cheese omelettes and sausage to cereal and yogurt. The room was clean.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Terri

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely clean comfortable hotel. The only improvement would if streaming on TV was possible. But overall an excellent hotel
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

James

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean and nice.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Pamela

Liked: Cleanliness, amenities, property conditions & facilities
Staff is very nice! The rooms are clean and comfortable.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Walt

Liked: Cleanliness, staff & service, property conditions & facilities
Easy to get there from the highway exit.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Brandy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Friendly staff clean rooms
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Shelby

Liked: Cleanliness, staff & service, property conditions & facilities
Great
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Ashley

Liked: Cleanliness, staff & service, amenities
Room was clean. Area was quiet. Cookie hour was nice and the breakfast had lots of options.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Jessica

Great breakfast, great rooms and comfy beds.
Stayed 1 night in May 2025
Verified

10/10 Excellent

Roderick

Liked: Cleanliness, amenities, property conditions & facilities
A clean room and a nice room, with a nice bathroom, comfortable bed, tv with a good selection of channels free, the warm chocolate chip cookies with milk at 8 pm was very nice complimentary, and complimentary breakfast was very good! Staff was very friendly and helpful! Nice swimming pool
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Ray

Liked: Cleanliness, staff & service, property conditions & facilities
Great hotel
Stayed 6 nights in Jul 2025
Verified

10/10 Excellent

Arielle

Liked: Cleanliness, amenities, property conditions & facilities
Room was absolutely perfect…. Great space and very clean
Stayed 1 night in Dec 2025