Illinois may have travel restrictions in place, including self-quarantine, due to COVID-19.

Find out moreOpens in new tab or window

Hotels in Southwest Illinois

Search over 343 hotels from $53

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Top Rated Southwest Illinois Hotels

Don't see what you're looking for?
See all available properties in Southwest Illinois
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Southwest Illinois

  • Super 8 by Wyndham Troy IL/St. Louis Area
    Super 8 by Wyndham Troy IL/St. Louis Area
    910 Edwardsville Rd, Troy, IL
    The price is $60 per night from Jan 26 to Jan 27
    3.7/5Good! (37 reviews)
    Super 8 by Wyndham Troy IL/St. Louis Area
  • Super 8 by Wyndham Mt. Vernon IL
    Super 8 by Wyndham Mt. Vernon IL
    401 S 44th St, Mount Vernon, IL
    The price is $53 per night from Jan 26 to Jan 27
    3.5/5Good! (43 reviews)
    Super 8 by Wyndham Mt. Vernon IL
  • Super 8 by Wyndham Carbondale
    Super 8 by Wyndham Carbondale
    1180 E Main St, Carbondale, IL
    The price is $56 per night from Jan 26 to Jan 27
    3.4/5Good! (66 reviews)
    Super 8 by Wyndham Carbondale

Pet Friendly Southwest Illinois Hotels

  • La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
    La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
    136 Regency Park, O'Fallon, IL
    The price is $59 per night from Jan 26 to Jan 27
    3.9/5Good! (17 reviews)
    La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
  • Red Roof Inn St Louis - Troy, IL
    Red Roof Inn St Louis - Troy, IL
    2030 Formosa Road, Troy, IL
    The price is $63 per night from Jan 22 to Jan 23
    3.7/5Good! (74 reviews)
    Red Roof Inn St Louis - Troy, IL
  • La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
    La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
    6 Gateway Dr, Collinsville, IL
    The price is $63 per night from Jan 26 to Jan 27
    3.6/5Good! (29 reviews)
    La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

Recent Reviews