Hotels in Southern Minnesota
Search over 667 hotels from $55
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Top Rated Southern Minnesota Hotels
Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
76.79 mi from city center
Guests of Kahler Inn and Suites - Mayo Clinic Area enjoy a fitness center, free WiFi in public areas, and a meeting room. If you drive, self parking is USD 15.00 per day, and there's also an airport shuttle. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and securing valuables. Additional amenities include a business center, coffee/tea in a common area, and an arcade/game room.
Free WiFi
Pet Friendly
La Quinta Inn & Suites by Wyndham Rochester
4353 Canal Pl SE, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
77.35 mi from city center
Built in 2014, the brand new La Quinta Inn & Suites by Wyndham Rochester features 2 indoor pools, a children's pool, and a fitness center. There's free parking if you drive. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. Other amenities at this family-friendly hotel include a spa tub, free WiFi in public areas, and conference space.
Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
76.87 mi from city center
At Kahler Grand Hotel, guests enjoy features like an indoor pool, a 24-hour fitness center, and a sauna. Valet parking is offered for USD 24.00 per day. The front desk has multilingual staff on hand 24/7 to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include free WiFi in public areas, a conference center, and a 24-hour business center.
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
1125 2nd St Sw, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
76.2 mi from city center
Guests staying at SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys enjoy an indoor pool, a 24-hour fitness center, and a spa tub. There's free parking, and an airport shuttle (available 24 hours) for USD 15 per person one-way. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include free WiFi in public areas, a 24-hour business center, and a computer station.
DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area
150 S Broadway, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
77.02 mi from city center
At DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area, guests enjoy an indoor pool, a 24-hour fitness center, and a sauna. Parking is available for USD 17.27 per night (USD 22 per night for valet parking), and there's also limo/town car service. The front desk is staffed 24/7 to help with dry cleaning/laundry, concierge services, and luggage storage. Additional amenities include free WiFi in public areas, conference space, and a 24-hour business center.
Comfort Suites
4141 Maine Avenue SE, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
77.31 mi from city center
Guests staying at Comfort Suites enjoy an indoor pool, a fitness center, and a spa tub. There's free parking, as well as a free airport shuttle during limited hours. The front desk is staffed 24/7 to help with dry cleaning or laundry, and answer any questions about the accommodations. Additional amenities include free WiFi in public areas, a 24-hour business center, and a computer station.
AmericInn by Wyndham Mankato Event Center
240 Stadium Road, Mankato, MN
Free Cancellation
Reserve now, pay when you stay
6.12 mi from city center
At AmericInn by Wyndham Mankato Event Center, guests enjoy an indoor pool, a fitness center, and a spa tub. If you drive, take advantage of free parking. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and luggage storage. Additional amenities include free WiFi in public areas, a conference center, and a 24-hour business center.
Hilton Rochester Mayo Clinic Area
10 East Center Street, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
77.02 mi from city center
Built in 2019, the brand new Hilton Rochester Mayo Clinic Area features a full-service spa, an indoor pool, and a 24-hour fitness center. Valet parking is offered for USD 26 per night. The 24-hour front desk has staff standing by to help with concierge services, dry cleaning/laundry, and luggage storage. Other amenities at this spa hotel include a spa tub, a sauna, and free WiFi in public areas.
Pool
Free WiFi
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
1517 16th St Sw, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
75.88 mi from city center
Guests of Best Western Rochester Hotel Mayo Clinic Area/St. Mary's enjoy free WiFi in public areas, a business center, and a TV in a common area. If you drive, take advantage of free parking. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. This smoke-free hotel also has wedding services.
Ramada by Wyndham Rochester Mayo Clinic Area
1625 Broadway Ave S, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
77.02 mi from city center
Ramada by Wyndham Rochester Mayo Clinic Area features an indoor pool, a children's pool, and a 24-hour fitness center. If you drive, take advantage of free parking. The 24-hour front desk has multilingual staff ready to assist with securing valuables and luggage storage. Additional amenities include free WiFi in public areas, a conference center, and a 24-hour business center.
Aspen Suites
1211 2nd Street, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
76.07 mi from city center
Guests of Aspen Suites have access to an indoor pool, a fitness center, and a spa tub. There's free parking and a free area shuttle. The front desk is staffed 24/7 to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include free WiFi in public areas, a 24-hour business center, and coffee/tea in a common area.
Hilton Garden Inn Rochester Downtown, MN
225 S Broadway, Rochester, MN
Free Cancellation
Reserve now, pay when you stay
77.01 mi from city center
At Hilton Garden Inn Rochester Downtown, MN, guests enjoy features like an indoor pool, a 24-hour fitness center, and a spa tub. Parking is available for USD 16 per night (USD 18 per night for valet parking), and there's also a free area shuttle. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include free WiFi in public areas, conference space, and a 24-hour business center.
Pool
Free WiFi
Don't see what you're looking for?
See all available properties in Southern Minnesota
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels
4 properties

3 Star Hotels
60 properties
Luxury Hotels in Southern Minnesota
5th Avenue Inn and Suites
20 5th Ave NW, Rochester, MN
3.3/5 (15 reviews)
Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
3.4/5Good! (66 reviews)
AmericInn by Wyndham Blue Earth
1495 Domes Dr, Blue Earth, MN
4.3/5Excellent! (10 reviews)
Pet Friendly Southern Minnesota Hotels
La Quinta Inn & Suites by Wyndham Rochester
4353 Canal Pl SE, Rochester, MN
4.2/5Excellent! (34 reviews)
GuestHouse Rochester
435 16th Ave Nw, Rochester, MN
4/5Very Good! (44 reviews)
Microtel Inn & Suites by Wyndham Rochester South
4165 Maine Ave SE, Rochester, MN
4.1/5Very Good! (26 reviews)
Recent Reviews

Kahler Grand Hotel
5/5 Excellent
A verified traveler stayed at Kahler Grand Hotel
Posted 1 month ago

Kahler Inn and Suites - Mayo Clinic Area
5/5 Excellent
A verified traveler stayed at Kahler Inn and Suites - Mayo Clinic Area
Posted 3 months ago

Comfort Suites
5/5 Excellent
A verified traveler stayed at Comfort Suites
Posted 8 months ago