Business Hotels in Southeast Illinois, IL
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Featured Southeast Illinois Business Hotels

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
100 E Front St Metropolis IL
$117 nightly
The price is $130 total per night
$130 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Guests staying at Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination enjoy a casino, free WiFi in public areas, and express check-out. If you drive, put free parking to good use. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include free newspapers, an ATM, and a vending machine.
Pet friendly
Parking included

Super 8 by Wyndham Mattoon
205 Mcfall Rd Mattoon IL
Free Cancellation
Reserve now, pay when you stay
$62 nightly
The price is $69 total per night
$69 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of Super 8 by Wyndham Mattoon enjoy access to free WiFi in public areas, meeting rooms, and a business center. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include free newspapers, a vending machine, and a banquet hall.
Breakfast included
Parking included

Holiday Inn Express & Suites Effingham by IHG
1604 West Fayette Avenue Effingham IL
Free Cancellation
$103 nightly
The price is $115 total per night
$115 total
Dec 14 - Dec 15
Total with taxes and fees
Guests of Holiday Inn Express & Suites Effingham by IHG have access to an indoor pool, a gym, and a sauna. Self parking is offered for USD 1 per day. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include free WiFi in public areas, a hot tub, and a business center.
Pool
Hot Tub

Holiday Inn Express & Suites Mattoon by IHG
121 Swords Dr Mattoon IL
Free Cancellation
$82 nightly
The price is $92 total per night
$92 total
Dec 14 - Dec 15
Total with taxes and fees
At Holiday Inn Express & Suites Mattoon by IHG, guests enjoy features like an indoor pool, a 24-hour gym, and free WiFi in public areas. Free parking is included with your stay. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include conference space, a 24-hour business center, and a computer station.
Pool
Breakfast included

Country Inn & Suites by Radisson, Effingham, IL
1200 N Raney Effingham IL
Free Cancellation
$94 nightly
The price is $104 total per night
$104 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
At Country Inn & Suites by Radisson, Effingham, IL, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The 24-hour front desk has staff always at the ready. Additional amenities include a business center, coffee/tea in a common area, and laundry facilities.
Pool
Breakfast included

Unique Suites Hotel
920 W Lincoln Ave Charleston IL
Free Cancellation
Reserve now, pay when you stay
$108 nightly
The price is $119 total per night
$119 total
Dec 14 - Dec 15
Total with taxes and fees
Guests of Unique Suites Hotel enjoy a gym, free WiFi in public areas, and meeting rooms. A stay here includes free parking. Additional amenities include conference space, a seasonal outdoor pool, and express check-out.
Pool
Breakfast included

Clarion Pointe Mattoon near University
206 Mcfall Rd Mattoon IL
Free Cancellation
Reserve now, pay when you stay
$86 nightly
The price is $96 total per night
$96 total
Dec 18 - Dec 19
Total with taxes and fees
At Clarion Pointe Mattoon near University, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with luggage storage and dry cleaning/laundry. Additional amenities include conference space, a 24-hour business center, and a computer station.
Pool
Parking included

Holiday Inn Effingham by IHG
1301 Avenue Of Mid America Effingham IL
Free Cancellation
$101 nightly
The price is $113 total per night
$113 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Guests staying at Holiday Inn Effingham by IHG enjoy an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. Multilingual staff at the front desk are standing by 24/7 to help with luggage storage, dry cleaning/laundry, and tours or tickets. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Parking included

Best Western Heartland Inn
1416 Broadway Avenue East Mattoon IL
Free Cancellation
Reserve now, pay when you stay
$81 nightly
The price is $90 total per night
$90 total
Dec 14 - Dec 15
Total with taxes and fees
Guests of Best Western Heartland Inn enjoy a gym, free WiFi in public areas, and coffee in a common area. There's free parking if you drive. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, securing valuables, and luggage storage. Additional amenities include a computer station, express check-in, and express check-out.
Breakfast included
Pet friendly

Baymont by Wyndham Effingham
1811 W Fayette Avenue Effingham IL
Free Cancellation
Reserve now, pay when you stay
$73 nightly
The price is $81 total per night
$81 total
Dec 15 - Dec 16
Total with taxes and fees
At Baymont by Wyndham Effingham, guests have access to a 24-hour gym, free WiFi in public areas, and a 24-hour business center. There's free parking if you drive. The 24-hour front desk has staff always at the ready. Additional amenities include coffee/tea in a common area, a meeting room, and free newspapers.
Breakfast included
Pet friendly

Quality Inn
2200 S Court Street Grayville IL
Free Cancellation
Reserve now, pay when you stay
$70 nightly
The price is $77 total per night
$77 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
At Quality Inn, guests have access to a gym, free WiFi in public areas, and coffee in a common area. There's free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a microwave in a common area, a computer station, and laundry facilities.
Breakfast included
Pet friendly

Comfort Suites Effingham Central
1310 W Fayette Rd Effingham IL
Free Cancellation
Reserve now, pay when you stay
$98 nightly
The price is $109 total per night
$109 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests staying at Comfort Suites Effingham Central enjoy an indoor pool, a gym, and a sauna. A stay here includes free parking. The 24-hour front desk has staff always at the ready. Additional amenities include free WiFi in public areas, a business center, and coffee/tea in a common area.
Pool
Breakfast included

Fairfield Inn & Suites Marriott Effingham
1111 North Henrietta Street Effingham IL
Free Cancellation
Reserve now, pay when you stay
$96 nightly
The price is $107 total per night
$107 total
Dec 21 - Dec 22
Total with taxes and fees
At Fairfield Inn & Suites Marriott Effingham, guests enjoy an indoor pool, a gym, and free WiFi in public areas. There's free parking if you drive. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include a hot tub, meeting rooms, and a business center.

Hampton Inn & Suites Effingham
1305 N Keller Dr Effingham IL
Free Cancellation
Reserve now, pay when you stay
$103 nightly
The price is $115 total per night
$115 total
Dec 18 - Dec 19
Total with taxes and fees
Guests of Hampton Inn & Suites Effingham have access to an indoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and concierge services. Additional amenities include coffee/tea in a common area, a meeting room, and laundry facilities.
Pool
Breakfast included

Quality Inn & Suites Mattoon South
4922 Paradise Rd Mattoon IL
Free Cancellation
Reserve now, pay when you stay
$83 nightly
The price is $93 total per night
$93 total
Dec 25 - Dec 26
Total with taxes and fees
Guests of Quality Inn & Suites Mattoon South enjoy a gym, free WiFi in public areas, and a business center. Free parking is included with your stay. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a seasonal outdoor pool, a computer station, and laundry facilities.
Pool
Breakfast included
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See all available properties in Southeast Illinois
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southeast Illinois hotels essential information
Accommodation | 1,010 hotels |
|---|---|
Lowest Price | $69 |
Highest Price | $130 |
Popular hotels | Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination, Super 8 by Wyndham Mattoon, Holiday Inn Express & Suites Effingham by IHG, Holiday Inn Express & Suites Mattoon by IHG, Country Inn & Suites by Radisson, Effingham, IL, Unique Suites Hotel, Clarion Pointe Mattoon near University, Holiday Inn Effingham by IHG, Best Western Heartland Inn, Baymont by Wyndham Effingham, Quality Inn, Comfort Suites Effingham Central, Fairfield Inn & Suites Marriott Effingham, Hampton Inn & Suites Effingham, Quality Inn & Suites Mattoon South |
Recent Business Hotels Reviews

La Quinta Inn & Suites by Wyndham Effingham
5/5 Excellent
"The room was spacious and clean. Bed was pretty comfortable. Hot breakfast food was welcomed."
A verified traveler stayed at La Quinta Inn & Suites by Wyndham Effingham
Posted 2 days ago
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