Hotels in South Main

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  • Mar 23 - Mar 24
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Featured Hotels in South Main

Wingate Houston near NRG Park/Medical Center

Wingate Houston near NRG Park/Medical Center

3 out of 5
8600 Kirby Drive, Houston, TX, 77054
Free Cancellation
Reserve now, pay when you stay
0.64 mi from South Main
The price is $89 per night
$89
per night
Apr 5 - Apr 6
Renovated in 2021, Wingate Houston near NRG Park/Medical Center offers a gym, free WiFi in public areas, and a conference center. There's free parking if you drive. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Additional amenities include a 24-hour business center, a computer station, and laundry facilities.
Wyndham Houston near NRG Park/Medical Center

Wyndham Houston near NRG Park/Medical Center

3.5 out of 5
8686 Kirby Drive, Houston, TX, 77054
Free Cancellation
Reserve now, pay when you stay
0.47 mi from South Main
The price is $112 per night
$112
per night
Apr 5 - Apr 6
Guests staying at Wyndham Houston near NRG Park/Medical Center enjoy access to 2 outdoor pools, a 24-hour gym, and free WiFi in public areas. If you plan to drive, free parking is available. Multilingual staff at the front desk are standing by 24/7 to help with securing valuables, concierge services, and luggage storage. Additional amenities include a spa tub, conference space, and a 24-hour business center.
Quality Inn & Suites NRG Park - Medical Center

Quality Inn & Suites NRG Park - Medical Center

2.5 out of 5
2364 South Loop W, Houston, TX, 77054
Free Cancellation
Reserve now, pay when you stay
0.42 mi from South Main
The price is $71 per night
$71
per night
Apr 4 - Apr 5
Quality Inn & Suites NRG Park - Medical Center features an outdoor pool, a children's pool, and a gym. There's free parking and a free area shuttle. The front desk has multilingual staff on hand 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Other amenities at this family-friendly hotel include free WiFi in public areas, conference space, and a 24-hour business center.
Candlewood Suites Houston Medical Center, an IHG Hotel

Candlewood Suites Houston Medical Center, an IHG Hotel

2.5 out of 5
10025 S Main Street, Houston, TX, 77025
0.53 mi from South Main
The price is $94 per night
$94
per night
Mar 29 - Mar 30
At Candlewood Suites Houston Medical Center, an IHG Hotel, guests have access to a 24-hour gym, free WiFi in public areas, and a 24-hour business center. There's free parking and a free area shuttle. The 24-hour front desk has staff standing by to help with luggage storage and dry cleaning/laundry. Additional amenities include coffee/tea in a common area, a computer station, and express check-out.
Comfort Suites near Texas Medical Center - NRG Stadium

Comfort Suites near Texas Medical Center - NRG Stadium

2.5 out of 5
1055 Mcnee Rd, Houston, TX, 77054
1.14 mi from South Main
The price is $99 per night
$99
per night
Apr 8 - Apr 9
Renovated in 2021, Comfort Suites near Texas Medical Center - NRG Stadium offers a gym, free WiFi in public areas, and a 24-hour business center. Free parking is included with your stay. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a seasonal outdoor pool, laundry facilities, and a convenience store.
Rest Up Inn

Rest Up Inn

3 out of 5
10015 South Main Street, Houston, TX, 77025
Free Cancellation
Reserve now, pay when you stay
0.67 mi from South Main
The price is $50 per night
$50
per night
Mar 26 - Mar 27
Guests of OYO Hotel Houston, TX near Medical Center/NRG Stadium enjoy access to free WiFi in public areas, a business center, and coffee in a common area. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a computer station and laundry facilities.
Comfort Suites Near Texas Medical Center - NRG Stadium

Comfort Suites Near Texas Medical Center - NRG Stadium

3.5 out of 5
1055 McNee Road East of Main Street, Houston, TX, 77054
1.16 mi from South Main
Comfort Suites Near Texas Medical Center - NRG Stadium features an outdoor pool, a gym, and a business center.
Medical Center Resort at NRG Stadium

Medical Center Resort at NRG Stadium

3000 West Bellfort Ave, Houston, TX, 77054
0.4 mi from South Main
Guests of Medical Center Resort at NRG Stadium have access to 4 outdoor pools, a 24-hour gym, and a 24-hour business center. If you drive, put free parking to good use. This apartment building also has barbecue grills.
Luxurious 2bd/2bth close 2 everything! Med/Central Area/Pool view

Luxurious 2bd/2bth close 2 everything! Med/Central Area/Pool view

Houston, TX
0.22 mi from South Main
Features of this apartment include an outdoor pool and a gym.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

South Main Long Term & Extended Stay Hotels

Luxury Hotels in South Main

    SpringHill Suites Houston Medical Center/NRG Park

    SpringHill Suites Houston Medical Center/NRG Park

    1400 Old Spanish Trl, Houston, TX, 77054
    The price is $144 per night from Apr 7 to Apr 8
    $144
    per night
    Apr 7 - Apr 8
    8.8/10 Excellent! (1,064 reviews)
    Ramada by Wyndham Houston Intercontinental Airport East

    Ramada by Wyndham Houston Intercontinental Airport East

    6115 Will Clayton Parkway, Humble, TX, 77338
    The price is $63 per night from Apr 4 to Apr 5
    $63
    per night
    Apr 4 - Apr 5
    7.2/10 Good! (1,868 reviews)
    Hyatt Place Houston / The Woodlands

    Hyatt Place Houston / The Woodlands

    1909 Research Forest Drive, The Woodlands, TX, 77380
    The price is $119 per night from Mar 24 to Mar 25
    $119
    per night
    Mar 24 - Mar 25
    8.6/10 Excellent! (1,001 reviews)

Pet Friendly South Main Hotels

    Club Quarters Hotel Downtown, Houston

    Club Quarters Hotel Downtown, Houston

    720 Fannin Street, Houston, TX, 77002
    The price is $123 per night from Apr 9 to Apr 10
    $123
    per night
    Apr 9 - Apr 10
    8/10 Very Good! (2,663 reviews)
    Hilton Americas-Houston

    Hilton Americas-Houston

    1600 Lamar Street, Houston, TX, 77010
    The price is $171 per night from Apr 4 to Apr 5
    $171
    per night
    Apr 4 - Apr 5
    9/10 Wonderful! (1,266 reviews)
    The Royal Sonesta Houston Galleria

    The Royal Sonesta Houston Galleria

    2222 West Loop South, Houston, TX, 77027
    The price is $152 per night from Apr 13 to Apr 14
    $152
    per night
    Apr 13 - Apr 14
    8.2/10 Very Good! (1,003 reviews)
South Main Hotels

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Great selection of hotels in South Main

Whether you're searching for hotels in South Main on business, or hunting for a family getaway, South Main hotel options are only a click away. Find hotels in South Main with the location, star-rating and facilities you need. Narrow your search results even further by star rating, hotel chain and amenities, such as free parking, babysitting services, or fitness centers. And with area maps, you can view South Main hotels close you are to the airport and nearby attractions.

South Main hotel reviews, photos and virtual tours

Thanks to photos and virtual tours, you can look before you book your South Main hotel reservation. Check out South Main hotel properties using interactive tools which allow you view hotel rooms, common areas and key features. On Orbitz, you can also learn more about hotels in South Main with unbiased reviews from verified South Main hotel guests. We ask guests to offer candid feedback on services, comfort, location, value and amenities.

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Forget Orbitz change or cancel fees on South Main hotels

On Orbitz, South Main hotel deals mean flexibility. If you need to change your South Main hotel reservations, or cancel your stay, Orbitz doesn't charge cancel or change fees. Orbitz also offers great selection on airline tickets, vacation packages, and car rental deals to so you can plan your trip to South Main all in one place.

 

Popular places to visit

Image for NRG Stadium

NRG Stadium

4.5/5(626 reviews)

Catch an event at NRG Stadium during your trip to Houston. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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NRG Stadium
Image for George R. Brown Convention Center

George R. Brown Convention Center

4/5(961 reviews)

Find out what's happening at George R. Brown Convention Center during your trip—a top convention center in Houston. Experience the acclaimed art scene and entertainment choices in this vibrant area.

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George R. Brown Convention Center
Image for Toyota Center

Toyota Center

4/5(967 reviews)

Catch an event at Toyota Center during your trip to Houston. Experience the acclaimed art scene and entertainment choices in this vibrant area.

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Toyota Center

Recent Reviews

  • Wyndham Houston near NRG Park/Medical Center

    Wyndham Houston near NRG Park/Medical Center

    5/5 Excellent
    "First day the parking situation was rough but overall stay was great ! Definitely will be booking next year for the rodeo again ! Other than the drunk people throwing up all in the elevator on Saturday night 😂😂😂"
    A verified traveler stayed at Wyndham Houston near NRG Park/Medical Center
    Posted 2 days ago
    Wyndham Houston near NRG Park/Medical Center

Areas Of South Main

Hotels Near